HitPredict

Interactor 1: RBBP4 (Q09028)
Histone-binding protein RBBP4 (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome-remodeling factor subunit RBAP48) (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48)
Gene: RBBP4

Interactor 2: MB3L2 (Q8NHZ7)
Methyl-CpG-binding domain protein 3-like 2 (MBD3-like protein 2)
Gene: MBD3L2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.619

Property	Details
Experiments	33961781, 15701600
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 425 Hs			1 208
+	Hs
		328538 RBBP4_HUMAN (1-425): 4.3e-124: 367: 100.00		MBD3_HUMAN (16-208): 4.64e-87: 260: 30.93
+	Hs
		1083320 RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20		MB3L2_HUMAN (1-208): 5.51e-93: 272: 100.00
+	Hs
		997938 RBBP4_HUMAN (1-425): 4.3e-124: 367: 100.00		MBD2_HUMAN (16-203): 4.85e-78: 241: 30.16
+	Hs
		328566 RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20		MBD3_HUMAN (16-208): 4.64e-87: 260: 30.93
+	Hs
		997830 RBBP4_HUMAN (1-425): 4.3e-124: 367: 100.00		MB3L1_HUMAN (23-207): 2.17e-79: 237: 40.96
+	Hs
		1083414 RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20		MBD2_HUMAN (16-203): 4.85e-78: 241: 30.16
+	Hs
		1083330 RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20		MB3L1_HUMAN (23-207): 2.17e-79: 237: 40.96
+	Dm
		1099165 CAF1_DROME (226-419): 3.68e-29: 119: 18.36		Q9VHB7_DROME (41-194): 7.97e-60: 192: 27.22