HitPredict

Interactor 1: EP300 (Q09472)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Interactor 2: SMRC2 (Q8TAQ2)
SWI/SNF complex subunit SMARCC2 (BRG1-associated factor 170) (BAF170) (SWI/SNF complex 170 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2)
Gene: SMARCC2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30110629
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Myb_DNA-binding~ZZ
Common GO terms	GO:0000785 - chromatin GO:0003713 - transcription coactivator activity GO:0005654 - nucleoplasm GO:0007399 - nervous system development GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2414 Hs			1 1214
+	Hs
		998950 EP300_HUMAN (1-2414): 0: 1113: 100.00		SMRC1_HUMAN (4-1082): 0: 957: 60.83
+	Hs
		232126 EP300_HUMAN (1-2414): 0: 1113: 100.00		KDM1A_HUMAN (253-543): 1.97e-43: 173: 15.00
+	Hs
		999262 EP300_HUMAN (1-2414): 0: 1113: 100.00		NCOR2_HUMAN (588-1208): 2.06e-32: 139: 14.22
+	Hs
		261484 EP300_HUMAN (1-2414): 0: 1113: 100.00		NCOR1_HUMAN (597-1154): 8.84e-32: 137: 10.86
+	Hs
		999163 EP300_HUMAN (1-2414): 0: 1113: 100.00		RERE_HUMAN (759-1212): 1.19e-09: 65: 16.17
+	Hs
		1123381 BRDT_HUMAN (1036-1159): 2.03e-33: 143: 29.84		SMRC2_HUMAN (1-1203): 0: 992: 100.00
+	Hs
		631516 BRD2_HUMAN (1035-1159): 9.57e-30: 131: 31.20		SMRC2_HUMAN (1-1203): 0: 992: 100.00
+	Hs
		1067063 BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48		SMRC2_HUMAN (1-1203): 0: 992: 100.00
+	Hs
		1123386 BRDT_HUMAN (1036-1159): 2.03e-33: 143: 29.84		SMRC1_HUMAN (4-1082): 0: 957: 60.83
+	Hs
		631538 BRD2_HUMAN (1035-1159): 9.57e-30: 131: 31.20		SMRC1_HUMAN (4-1082): 0: 957: 60.83
+	Hs
		1067081 BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48		SMRC1_HUMAN (4-1082): 0: 957: 60.83
+	At
		1195144 GTE11_ARATH (974-1307): 1.8e-43: 171: 17.58		SWI3B_ARATH (386-789): 1.61e-87: 293: 23.54
+	At
		1275616 GTE11_ARATH (974-1307): 1.8e-43: 171: 17.58		SWI3C_ARATH (383-990): 2.21e-79: 280: 20.82
+	At
		1258938 GTE11_ARATH (974-1307): 1.8e-43: 171: 17.58		SWI3A_ARATH (422-725): 1.3e-64: 230: 22.83
+	Hs
		1378167 NCOA3_HUMAN (1849-2386): 7.64e-52: 204: 21.89		NCOR2_HUMAN (588-1208): 2.06e-32: 139: 14.22
+	Hs
		261619 NCOA3_HUMAN (1849-2386): 7.64e-52: 204: 21.89		NCOR1_HUMAN (597-1154): 8.84e-32: 137: 10.86
+	Hs
		261596 BAZ1A_HUMAN (889-1176): 3.58e-51: 202: 21.31		NCOR1_HUMAN (597-1154): 8.84e-32: 137: 10.86
+	At
		1308015 GCN5_ARATH (1000-1159): 2.86e-39: 158: 27.98		TAD2A_ARATH (514-964): 2.09e-41: 162: 16.24
+	At
		1308007 GCN5_ARATH (1000-1159): 2.86e-39: 158: 27.98		TAD2B_ARATH (511-952): 2.99e-41: 161: 13.41
+	Hs
		261613 TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50		NCOR1_HUMAN (597-1154): 8.84e-32: 137: 10.86