HitPredict

Interactor 1: H33A (C0HL66)
Histone H3.3A (H3.A)
Gene: His3.3A

Interactor 2: PCL (Q24459)
Polycomb protein Pcl (Polycomblike protein)
Gene: PCL

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	17762866
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005700 - polytene chromosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Dm			1 1043
+	Hs
		998817 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		CSR2B_HUMAN (518-906): 7.26e-116: 377: 21.21
+	Hs
		998998 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		MTF2_HUMAN (344-824): 8.52e-112: 360: 25.45
+	Hs
		998414 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		PHF19_HUMAN (348-706): 7.3e-111: 357: 30.08
+	Hs
		210256 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		PHF1_HUMAN (323-742): 3.93e-88: 296: 27.42
+	Hs
		998902 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		ASH2L_HUMAN (475-776): 2.47e-55: 205: 14.37
+	Hs
		998942 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		KMT2B_HUMAN (269-600): 7.06e-38: 157: 14.45
+	Mm
		147453 H33_MOUSE (1-136): 1.13e-59: 182: 100.00		KMT2B_MOUSE (269-600): 3.15e-37: 155: 14.45
+	Hs
		998234 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		KMT2A_HUMAN (184-601): 1.16e-34: 146: 12.04
+	Hs
		1016789 H33_HUMAN (1-136): 1.13e-59: 182: 100.00		KMT2A_HUMAN (184-601): 1.16e-34: 146: 12.04
+	Hs
		998324 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		CHD4_HUMAN (409-579): 1.81e-34: 145: 18.08
+	Hs
		1016866 H33_HUMAN (1-136): 1.13e-59: 182: 100.00		CHD4_HUMAN (409-579): 1.81e-34: 145: 18.08
+	Zm
		40785 K7U3E1_MAIZE (1-136): 3.11e-60: 184: 94.85		A0A1D6NA80_MAIZE (41-338): 6.45e-33: 140: 16.40
+	Mm
		59101 H33_MOUSE (1-136): 1.13e-59: 182: 100.00		CHD5_MOUSE (316-578): 7.21e-32: 137: 11.51
+	Hs
		998577 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		CHD5_HUMAN (414-578): 3.74e-31: 135: 15.98
+	Hs
		998466 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		SRCAP_HUMAN (22-354): 2.47e-10: 67.2: 17.22
+	Hs
		998565 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		KMT2C_HUMAN (33-445): 8.01e-10: 65.5: 12.06
+	Hs
		161446 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		KMT2D_HUMAN (2-408): 2.62e-09: 63.9: 11.33
+	Hs
		998317 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		MDC1_HUMAN (24-346): 5.72e-09: 62.6: 19.95
+	Hs
		1016860 H33_HUMAN (1-136): 1.13e-59: 182: 100.00		MDC1_HUMAN (24-346): 5.72e-09: 62.6: 19.95
+	Mm
		107469 H33_MOUSE (1-136): 1.13e-59: 182: 100.00		F8WI37_MOUSE (12-426): 8.21e-09: 62.4: 10.98