Protein: ZC21C
Zinc finger C2HC domain-containing protein 1C

Gene: ZC21C, ZC2HC1C
Organism: Homo sapiens
Interactions: 128
UniProt ID: Q53FD0

Gene Ontology (top 5):
GO:0008270 - zinc ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1090689

TRAF2
TNF receptor-associated factor 2

3

2

High-throughput

0.675

High

783285

TRI23
E3 ubiquitin-protein ligase TRIM23

3

0

High-throughput

0.646

High

1198832

KAT5
Histone acetyltransferase KAT5

3

0

High-throughput

0.632

High

1198835

HOOK2
Protein Hook homolog 2

3

1

High-throughput

0.616

High

1198845

SIKE1
Suppressor of IKBKE 1

3

1

High-throughput

0.607

High

572006

TRI27
Zinc finger protein RFP

2

0

High-throughput

0.606

High

773747

ACTN2
Alpha-actinin-2

3

1

High-throughput

0.597

High

570442

GFAP
Glial fibrillary acidic protein

2

2

High-throughput

0.583

High

783704

ZNF76
Zinc finger protein 76

2

0

High-throughput

0.580

High

1198821

ZN655
Zinc finger protein 655

2

0

High-throughput

0.580

High

1093837

TRAF1
TNF receptor-associated factor 1

1

1

High-throughput

0.573

High

1198869

TRIM1
Probable E3 ubiquitin-protein ligase MID2

1

5

High-throughput

0.573

High

943771

UBS3A
Ubiquitin-associated and SH3 domain-containing protein A

2

1

High-throughput

0.553

High

1042011

LMNB2
Lamin-B2

2

2

High-throughput

0.553

High

1063302

GOGA2
Golgin subfamily A member 2

2

2

High-throughput

0.553

High

1198844

LZTS2
Leucine zipper putative tumor suppressor 2

2

1

High-throughput

0.553

High

1198854

KIF9
Kinesin-like protein KIF9

2

1

High-throughput

0.553

High

1198860

FGOP2
FGFR1 oncogene partner 2

2

1

High-throughput

0.553

High

1198862

GOG6A
Golgin subfamily A member 6A

2

2

High-throughput

0.553

High

1198868

RABX5
Rab5 GDP/GTP exchange factor

1

0

High-throughput

0.549

High

1198833

TRI63
E3 ubiquitin-protein ligase TRIM63

1

3

High-throughput

0.541

High

1198847

TRI55
Tripartite motif-containing protein 55

1

3

High-throughput

0.541

High

51426

FSD2
Fibronectin type III and SPRY domain-containing protein 2

1

4

High-throughput

0.523

High

730634

1433S
14-3-3 protein sigma

1

1

High-throughput

0.523

High

1198813

K1C40
Keratin, type I cytoskeletal 40

1

2

High-throughput

0.523

High

1095663

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

0

High-throughput

0.518

High

777396

K1C20
Keratin, type I cytoskeletal 20

1

1

High-throughput

0.494

High

1139725

SETB1
Histone-lysine N-methyltransferase SETDB1

1

0

High-throughput

0.493

High

1198875

RNF11
RING finger protein 11

1

0

High-throughput

0.493

High

116861

I6L9F6
NEFL protein

1

3

High-throughput

0.470

High

451172

NFL
Neurofilament light polypeptide

1

3

High-throughput

0.470

High

833285

PERI
Peripherin

1

2

High-throughput

0.470

High

966402

1433G
14-3-3 protein gamma

1

1

High-throughput

0.470

High

1193595

Q49AR9
ANKS1A protein

1

1

High-throughput

0.470

High

1194541

Q4G0R1
PIBF1 protein

1

1

High-throughput

0.470

High

1198877

TF3C3
General transcription factor 3C polypeptide 3

1

1

High-throughput

0.470

High

1198811

RN123
E3 ubiquitin-protein ligase RNF123

1

0

High-throughput

0.458

High

385808

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

3

High-throughput

0.439

High

1198828

PIBF1
Progesterone-induced-blocking factor 1

1

1

High-throughput

0.439

High

1198830

ANS1A
Ankyrin repeat and SAM domain-containing protein 1A

1

1

High-throughput

0.439

High

47264

A0A6Q8KRG2
Golgin subfamily A member 2

1

2

High-throughput

0.417

High

618041

K1C15
Keratin, type I cytoskeletal 15

4

0

High-throughput

0.368

High

1198879

EMIL1
EMILIN-1

3

0

High-throughput

0.352

High

1198865

TFP11
Tuftelin-interacting protein 11

3

0

High-throughput

0.346

High

1198809

MTUS2
Microtubule-associated tumor suppressor candidate 2

2

0

High-throughput

0.334

High

64537

CC88B
Coiled-coil domain-containing protein 88B

2

0

High-throughput

0.316

High

164581

TNPO2
Transportin-2

2

0

High-throughput

0.316

High

180301

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

2

0

High-throughput

0.316

High

220777

PPIP1
Proline-serine-threonine phosphatase-interacting protein 1

2

0

High-throughput

0.316

High

225597

AAKB2
5'-AMP-activated protein kinase subunit beta-2

2

0

High-throughput

0.316

High

250257

VINEX
Vinexin

2

0

High-throughput

0.316

High

269226

HSF2B
Heat shock factor 2-binding protein

2

0

High-throughput

0.316

High

292354

RA51D
DNA repair protein RAD51 homolog 4

2

0

High-throughput

0.316

High

348865

CLIC3
Chloride intracellular channel protein 3

2

0

High-throughput

0.316

High

684262

DDX6
Probable ATP-dependent RNA helicase DDX6

2

0

High-throughput

0.316

High

853802

MK09
Mitogen-activated protein kinase 9

2

0

High-throughput

0.316

High

1118875

BYST
Bystin

2

0

High-throughput

0.316

High

1179949

CCD57
Coiled-coil domain-containing protein 57

2

0

High-throughput

0.316

High

1198808

ACTMP
Actin maturation protease

2

0

High-throughput

0.316

High

1198812

C102B
Coiled-coil domain-containing protein 102B

2

0

High-throughput

0.316

High

1198814

RINT1
RAD50-interacting protein 1

2

0

High-throughput

0.316

High

1198815

NOXA1
NADPH oxidase activator 1

2

0

High-throughput

0.316

High

1198817

F90A1
Protein FAM90A1

2

0

High-throughput

0.316

High

1198818

VPS52
Vacuolar protein sorting-associated protein 52 homolog

2

0

High-throughput

0.316

High

1198820

KASH5
Protein KASH5

2

0

High-throughput

0.316

High

1198826

BICD2
Protein bicaudal D homolog 2

2

0

High-throughput

0.316

High

1198831

GOGA1
Golgin subfamily A member 1

2

0

High-throughput

0.316

High

1198834

GASP2
G-protein coupled receptor-associated sorting protein 2

2

0

High-throughput

0.316

High

1198836

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

2

0

High-throughput

0.316

High

1198837

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.316

High

1198840

CIB3
Calcium and integrin-binding family member 3

2

0

High-throughput

0.316

High

1198843

PFD5
Prefoldin subunit 5

2

0

High-throughput

0.316

High

1198846

EFC4B
EF-hand calcium-binding domain-containing protein 4B

2

0

High-throughput

0.316

High

1198848

NDEL1
Nuclear distribution protein nudE-like 1

2

0

High-throughput

0.316

High

1198849

KTBL1
KATNB1-like protein 1

2

0

High-throughput

0.316

High

1198850

ENKD1
Enkurin domain-containing protein 1

2

0

High-throughput

0.316

High

1198851

CARD9
Caspase recruitment domain-containing protein 9

2

0

High-throughput

0.316

High

1198852

ARMC7
Armadillo repeat-containing protein 7

2

0

High-throughput

0.316

High

1198855

NEK6
Serine/threonine-protein kinase Nek6

2

0

High-throughput

0.316

High

1198856

CABP5
Calcium-binding protein 5

2

0

High-throughput

0.316

High

1198863

SPN90
NCK-interacting protein with SH3 domain

2

0

High-throughput

0.316

High

1198867

NDOR1
NADPH-dependent diflavin oxidoreductase 1

2

0

High-throughput

0.316

High

1198870

OSGI1
Oxidative stress-induced growth inhibitor 1

2

0

High-throughput

0.316

High

1198872

MARE3
Microtubule-associated protein RP/EB family member 3

2

0

High-throughput

0.316

High

1198824

PNMA1
Paraneoplastic antigen Ma1

1

0

High-throughput

0.303

High

1198822

BANP
Protein BANP

1

0

High-throughput

0.299

High

1198823

CBY2
Protein chibby homolog 2

1

0

High-throughput

0.299

High

1198838

CC136
Coiled-coil domain-containing protein 136

1

0

High-throughput

0.299

High

1198841

SPAG5
Sperm-associated antigen 5

1

0

High-throughput

0.299

High

1154520

CC85B
Coiled-coil domain-containing protein 85B

1

0

High-throughput

0.282

High

801354

HSPA9
Stress-70 protein, mitochondrial

1

0

High-throughput

0.279

Low

1022616

LRP2
Low-density lipoprotein receptor-related protein 2

1

0

High-throughput

0.279

Low

1094459

IFT88
Intraflagellar transport protein 88 homolog

1

0

High-throughput

0.279

Low

1134934

CUL7
Cullin-7

1

0

High-throughput

0.279

Low

1198816

IT70A
Intraflagellar transport protein 70A

1

0

High-throughput

0.279

Low

1198819

FBXW8
F-box/WD repeat-containing protein 8

1

0

High-throughput

0.279

Low

1198829

IFT81
Intraflagellar transport protein 81 homolog

1

0

High-throughput

0.279

Low

1198839

IFT74
Intraflagellar transport protein 74 homolog

1

0

High-throughput

0.279

Low

1198842

NEB2
Neurabin-2

1

0

High-throughput

0.279

Low

1198853

IFT22
Intraflagellar transport protein 22 homolog

1

0

High-throughput

0.279

Low

1198857

IFT46
Intraflagellar transport protein 46 homolog

1

0

High-throughput

0.279

Low

1198858

GEPH
Gephyrin [Includes: Molybdopterin adenylyltransferase

1

0

High-throughput

0.279

Low

1198859

MA2C1
Alpha-mannosidase 2C1

1

0

High-throughput

0.279

Low

1198861

IFT57
Intraflagellar transport protein 57 homolog

1

0

High-throughput

0.279

Low

1198864

CT2NL
CTTNBP2 N-terminal-like protein

1

0

High-throughput

0.279

Low

1198866

IF172
Intraflagellar transport protein 172 homolog

1

0

High-throughput

0.279

Low

1198873

IFT52
Intraflagellar transport protein 52 homolog

1

0

High-throughput

0.279

Low

130967

HIP1
Huntingtin-interacting protein 1

1

0

High-throughput

0.268

Low

245964

KIF1B
Kinesin-like protein KIF1B

1

0

High-throughput

0.268

Low

301458

WFS1
Wolframin

1

0

High-throughput

0.268

Low

441539

CCKN
Cholecystokinin

1

0

High-throughput

0.268

Low

562092

LAMP2
Lysosome-associated membrane glycoprotein 2

1

0

High-throughput

0.268

Low

650205

FGFR3
Fibroblast growth factor receptor 3

1

0

High-throughput

0.268

Low

702448

CLAT
Choline O-acetyltransferase

1

0

High-throughput

0.268

Low

719936

HMOX2
Heme oxygenase 2

1

0

High-throughput

0.268

Low

843624

HD
Huntingtin

1

0

High-throughput

0.268

Low

937017

CASP6
Caspase-6

1

0

High-throughput

0.268

Low

981522

RAN
GTP-binding nuclear protein Ran

1

0

High-throughput

0.268

Low

986462

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

0

High-throughput

0.268

Low

1031906

NC2B
Protein Dr1

1

0

High-throughput

0.268

Low

1133872

NMDE3
Glutamate receptor ionotropic, NMDA 2C

1

0

High-throughput

0.268

Low

1198810

Q5SUL5
HLA class I histocompatibility antigen A alpha chain

1

0

High-throughput

0.268

Low

1198825

LMO3
LIM domain only protein 3

1

0

High-throughput

0.268

Low

1198827

JPH3
Junctophilin-3

1

0

High-throughput

0.268

Low

1198871

UBQL1
Ubiquilin-1

1

0

High-throughput

0.268

Low

1198874

SHLB1
Endophilin-B1

1

0

High-throughput

0.268

Low

1198878

Q9Y649
GW128

1

0

High-throughput

0.268

Low

1198876

FBX7
F-box only protein 7

1

0

High-throughput

0.261

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025