Protein: MED14
Mediator of RNA polymerase II transcription subunit 14 (Mediator complex subunit 14) (dRGR1)

Gene: MED14
Organism: Drosophila melanogaster
Interactions: 71
UniProt ID: Q9W0P8

Gene Ontology (top 5):
GO:0003712 - transcription coregulator activity
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0016592 - mediator complex
GO:0060260 - regulation of transcription initiation by RNA polymerase II
GO:0070847 - core mediator complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1302904

MED31
Mediator of RNA polymerase II transcription subunit 31

2

3

High-throughput

0.737

High

1428009

MED10
Mediator of RNA polymerase II transcription subunit 10

2

3

High-throughput

0.737

High

1428117

MED7
Mediator of RNA polymerase II transcription subunit 7

2

3

High-throughput

0.737

High

1485350

MED4
Mediator of RNA polymerase II transcription subunit 4

2

1

High-throughput

0.737

High

1485966

CDK8
Cyclin-dependent kinase 8

2

9

High-throughput

0.737

High

1269645

MED13
Mediator of RNA polymerase II transcription subunit 13

3

2

Small-scale

0.633

High

1472622

MED17
Mediator of RNA polymerase II transcription subunit 17

3

2

Small-scale

0.633

High

1487354

MED19
Mediator of RNA polymerase II transcription subunit 19

1

1

High-throughput

0.575

High

58520

MED8
Mediator of RNA polymerase II transcription subunit 8

2

1

High-throughput

0.571

High

674067

BRM
ATP-dependent helicase brm

2

12

High-throughput

0.571

High

1019307

MED20
Mediator of RNA polymerase II transcription subunit 20

2

1

High-throughput

0.571

High

1171940

Q24090
GH08712p

2

2

High-throughput

0.571

High

1263911

Q7K012
Brahma associated protein 55kD

2

2

High-throughput

0.571

High

1267078

MED29
Mediator of RNA polymerase II transcription subunit 29

2

1

High-throughput

0.571

High

1303638

OSA
Trithorax group protein osa

2

6

High-throughput

0.571

High

1321590

MED6
Mediator of RNA polymerase II transcription subunit 6

2

3

High-throughput

0.571

High

1377812

EBI
F-box-like/WD repeat-containing protein ebi

2

10

High-throughput

0.571

High

1471848

MED25
Mediator of RNA polymerase II transcription subunit 25

2

8

High-throughput

0.571

High

1473455

Q9VF03
Brahma associated protein 155 kDa

2

10

High-throughput

0.571

High

1482748

MED27
Mediator of RNA polymerase II transcription subunit 27

2

1

High-throughput

0.571

High

1485579

MED24
Mediator of RNA polymerase II transcription subunit 24

2

1

High-throughput

0.571

High

1487441

MED11
Mediator of RNA polymerase II transcription subunit 11

2

1

High-throughput

0.571

High

1487590

MED12
Mediator of RNA polymerase II transcription subunit 12

2

20

High-throughput

0.571

High

1488708

BAP60
Brahma-associated protein of 60 kDa

2

2

High-throughput

0.571

High

1489431

MED30
Mediator of RNA polymerase II transcription subunit 30

2

1

High-throughput

0.571

High

1489441

MED23
Mediator of RNA polymerase II transcription subunit 23

2

2

High-throughput

0.571

High

1489442

MED16
Mediator of RNA polymerase II transcription subunit 16

2

1

High-throughput

0.571

High

1489444

MED18
Mediator of RNA polymerase II transcription subunit 18

2

1

High-throughput

0.571

High

756510

ECR
Ecdysone receptor

1

20

Small-scale

0.552

High

1261440

Q7JQT8
LD41464p

2

0

High-throughput

0.547

High

1306460

INDRA
Zinc finger protein indra

2

0

High-throughput

0.547

High

1321532

ENC
Protein encore

2

6

High-throughput

0.521

High

1378957

Q960F7
SD03629p

2

5

High-throughput

0.521

High

1440714

LAR4
La-related protein Larp4B

2

2

High-throughput

0.521

High

1472594

Q9VEB9
Sequence-specific single-stranded DNA-binding protein, isoform A

2

7

High-throughput

0.521

High

1485617

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

2

16

High-throughput

0.521

High

1486609

Q9VUB7
PAX-interacting protein 1

2

11

High-throughput

0.521

High

1489378

Q9W0L7
ubiquitinyl hydrolase 1

2

3

High-throughput

0.521

High

84996

B7Z126
non-specific serine/threonine protein kinase

1

2

High-throughput

0.514

High

1440744

Q9I7U5
Centrobin, isoform A

1

12

Small-scale

0.489

High

1465851

MED26
Mediator of RNA polymerase II transcription subunit 26

1

1

Small-scale

0.479

High

1489445

MED15
Mediator of RNA polymerase II transcription subunit 15

1

11

High-throughput

0.479

High

197496

O18353
CHIP

1

1

High-throughput

0.445

High

1483019

MED1
Mediator of RNA polymerase II transcription subunit 1

1

3

High-throughput

0.445

High

1488746

Q9VYK0
Smrter, isoform D

1

8

High-throughput

0.445

High

57006

A1ZAK9
P-element somatic inhibitor, isoform A

1

5

High-throughput

0.437

High

628547

USP
Protein ultraspiracle

1

20

Small-scale

0.437

High

1378865

Q960D2
SD06673p

1

13

Small-scale

0.437

High

1484628

Q9VR42
Serine/threonine-protein kinase RIO3

1

2

High-throughput

0.437

High

53613

A1Z813
Secretory 24AB, isoform A

1

5

High-throughput

0.407

High

56963

A1ZAK7
LD35640p

1

5

High-throughput

0.407

High

616672

ARM
Armadillo segment polarity protein

1

11

High-throughput

0.407

High

1069945

Q0E996
Eukaryotic translation initiation factor 4 gamma 2

1

3

High-throughput

0.407

High

1343932

Q8SXP8
TAR DNA-binding protein 43

1

7

High-throughput

0.407

High

1346039

ENA
Protein enabled

1

5

High-throughput

0.407

High

1378346

Q95TT5
LD24616p

1

7

High-throughput

0.407

High

1409408

Q9BIW6
Brahma-associated protein 111kD

1

7

High-throughput

0.407

High

1482723

Q9VNF8
Protein transport protein SEC23

1

5

High-throughput

0.407

High

1489440

Q9W124
LD27920p

1

3

High-throughput

0.407

High

1489443

Q9W3G1
Uncharacterized protein, isoform A

1

10

High-throughput

0.407

High

900689

DSH
Segment polarity protein dishevelled

2

0

High-throughput

0.298

High

1346459

MESD
LDLR chaperone boca

2

0

High-throughput

0.298

High

1480278

Q9VL29
GEO11246p1

2

0

High-throughput

0.298

High

1428081

NEMO
NF-kappa-B essential modulator

1

0

High-throughput

0.249

Low

1488889

Q9VYZ8
GEO08286p1

1

0

High-throughput

0.249

Low

84736

UNR
RNA-binding protein Unr

1

0

High-throughput

0.232

Low

638678

MAM
Neurogenic protein mastermind

1

0

High-throughput

0.232

Low

1031665

UMPS
Uridine 5'-monophosphate synthase

1

0

High-throughput

0.232

Low

1203055

Q5BIL9
SD21168p

1

0

High-throughput

0.232

Low

1345911

Q8T485
AT10995p

1

0

High-throughput

0.232

Low

1488530

Q9VXZ3
Ben, isoform C

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025