HitPredict

Interactor 1: MCM2 (P49735)
DNA replication licensing factor Mcm2 (EC 3.6.4.12) (Minichromosome maintenance 2 protein) (DmMCM2)
Gene: MCM2

Interactor 2: Q494K2 (Q494K2)
Chromosome transmission fidelity 4 (LD47422p)
Gene: Ctf4

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.50	0.526

Property	Details
Experiments	21470422, 38944040
Identification Methods	two hybrid, anti tag coimmunoprecipitation
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 887 Dm			1 895
+	Dm
		1193029 MCM6_DROME (161-883): 0: 667: 27.14		Q494K2_DROME (1-895): 0: 576: 100.00
+	Sc
		713025 MCM2_YEAST (8-798): 0: 762: 46.50		CTF4_YEAST (14-762): 7.94e-131: 417: 15.25
+	Hs
		291908 MCM7_HUMAN (181-863): 0: 655: 28.49		WDHD1_HUMAN (1-877): 2.81e-166: 516: 26.83
+	Hs
		888233 MCM2_HUMAN (5-879): 0: 930: 64.07		FBXW7_HUMAN (7-251): 7.59e-58: 213: 18.07
+	Sc
		721405 MCM4_YEAST (2-846): 0: 714: 25.72		CTF4_YEAST (14-762): 7.94e-131: 417: 15.25
+	Sc
		713294 MCM5_YEAST (174-809): 0: 686: 29.36		CTF4_YEAST (14-762): 7.94e-131: 417: 15.25
+	Hs
		755873 MCM5_HUMAN (154-880): 0: 712: 28.95		GBB2_HUMAN (4-301): 4.8e-78: 258: 17.32
+	Hs
		756147 MCM7_HUMAN (181-863): 0: 655: 28.49		GBB2_HUMAN (4-301): 4.8e-78: 258: 17.32
+	Hs
		1128253 MCM6_HUMAN (164-868): 0: 681: 28.57		FBXW7_HUMAN (7-251): 7.59e-58: 213: 18.07
+	Hs
		755768 MCM4_HUMAN (10-853): 0: 778: 26.55		SNR40_HUMAN (419-657): 6.66e-20: 94.4: 10.20
+	Hs
		669966 MCM3_HUMAN (171-880): 0: 658: 30.29		FBXW7_HUMAN (7-251): 7.59e-58: 213: 18.07
+	Hs
		756294 MCM7_HUMAN (181-863): 0: 655: 28.49		FBXW7_HUMAN (7-251): 7.59e-58: 213: 18.07
+	Sc
		713287 MCM5_YEAST (174-809): 0: 686: 29.36		COPA_YEAST (125-503): 8.71e-45: 177: 7.35
+	Hs
		755956 MCM5_HUMAN (154-880): 0: 712: 28.95		A16L1_HUMAN (11-255): 6.08e-11: 68.3: 17.20
+	Hs
		756301 MCM7_HUMAN (181-863): 0: 655: 28.49		SNR40_HUMAN (419-657): 6.66e-20: 94.4: 10.20
+	Hs
		669922 MCM3_HUMAN (171-880): 0: 658: 30.29		A16L1_HUMAN (11-255): 6.08e-11: 68.3: 17.20
+	Hs
		756113 MCM7_HUMAN (181-863): 0: 655: 28.49		LIS1_HUMAN (346-620): 8.42e-10: 63.9: 6.07