Protein: MED1
Mediator of RNA polymerase II transcription subunit 1 (Mediator complex subunit 1) (Peroxisome proliferator-activated receptor-binding protein) (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TR-interacting protein 2) (TRIP-2)

Gene: MED1
Organism: Mus musculus
Interactions: 23
UniProt ID: Q925J9

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000151 - ubiquitin ligase complex
GO:0000785 - chromatin
GO:0000902 - cell morphogenesis
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1222890

ERR2
Steroid hormone receptor ERR2

1

20

High-throughput

0.554

High

700408

CEBPB
CCAAT/enhancer-binding protein beta

1

9

Small-scale

0.515

High

662687

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

8

High-throughput

0.481

High

1063104

GATA4
Transcription factor GATA-4

1

8

High-throughput

0.481

High

1222393

GATA6
Transcription factor GATA-6

1

8

High-throughput

0.481

High

59163

PRD16
Histone-lysine N-methyltransferase PRDM16

1

2

Small-scale

0.479

High

266838

CIDEA
Lipid transferase CIDEA

1

1

Small-scale

0.479

High

266910

PRGC1
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha

1

1

Small-scale

0.479

High

403247

FABP4
Fatty acid-binding protein, adipocyte

1

3

Small-scale

0.479

High

654817

PPARA
Peroxisome proliferator-activated receptor alpha

1

20

Small-scale

0.479

High

1064939

RUNX2
Runt-related transcription factor 2

1

2

Small-scale

0.479

High

1189831

DDB1
DNA damage-binding protein 1

1

3

Small-scale

0.479

High

1282993

DAPK1
Death-associated protein kinase 1

1

11

Small-scale

0.479

High

1282999

MED23
Mediator of RNA polymerase II transcription subunit 23

1

4

Small-scale

0.479

High

629419

PO5F1
POU domain, class 5, transcription factor 1

1

6

High-throughput

0.445

High

1190685

TF2L1
Transcription factor CP2-like protein 1

1

2

High-throughput

0.445

High

1274338

MED26
Mediator of RNA polymerase II transcription subunit 26

1

1

High-throughput

0.445

High

1298667

TAD2A
Transcriptional adapter 2-alpha

1

3

High-throughput

0.445

High

1341623

LUZP1
Leucine zipper protein 1

1

15

High-throughput

0.445

High

1365311

CDK9
Cyclin-dependent kinase 9

1

5

Small-scale

0.445

High

1365312

KAT2A
Histone acetyltransferase KAT2A

1

15

High-throughput

0.445

High

552462

UCP1
Mitochondrial brown fat uncoupling protein 1

1

8

Small-scale

0.437

High

1297787

A16L1
Autophagy-related protein 16-1

1

10

High-throughput

0.437

High


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Last updated: 11Aug2025