Protein: DUS16
Dual specificity protein phosphatase 16 (EC 3.1.3.16) (EC 3.1.3.48) (Mitogen-activated protein kinase phosphatase 7) (MAP kinase phosphatase 7) (MKP-7)

Gene: DUS16, DUSP16
Organism: Homo sapiens
Interactions: 236
UniProt ID: Q9BY84

Gene Ontology (top 5):
GO:0004721 - phosphoprotein phosphatase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1082629

MK14
Mitogen-activated protein kinase 14

10

20

Small-scale

0.979

High

800938

MK09
Mitogen-activated protein kinase 9

8

20

Small-scale

0.970

High

800827

MK08
Mitogen-activated protein kinase 8

7

20

Small-scale

0.961

High

659043

MK01
Mitogen-activated protein kinase 1

2

20

Small-scale

0.776

High

211058

BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1

1

3

High-throughput

0.691

High

254510

ROCK2
Rho-associated protein kinase 2

1

5

High-throughput

0.691

High

610779

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

1

2

High-throughput

0.691

High

1069646

STK38
Serine/threonine-protein kinase 38

1

3

High-throughput

0.691

High

1219833

ANKH1
Ankyrin repeat and KH domain-containing protein 1

1

6

High-throughput

0.691

High

1301345

KKCC2
Calcium/calmodulin-dependent protein kinase kinase 2

1

2

High-throughput

0.691

High

1316198

SIK2
Serine/threonine-protein kinase SIK2

1

4

High-throughput

0.691

High

1316221

E2AK4
eIF-2-alpha kinase GCN2

1

2

High-throughput

0.691

High

1316239

SIK3
Serine/threonine-protein kinase SIK3

1

3

High-throughput

0.691

High

683681

1433B
14-3-3 protein beta/alpha

3

20

High-throughput

0.656

High

165036

SC16A
Protein transport protein Sec16A

2

1

High-throughput

0.628

High

864875

MK10
Mitogen-activated protein kinase 10

1

20

Small-scale

0.618

High

1027864

DUS8
Dual specificity protein phosphatase 8

1

16

High-throughput

0.618

High

1316190

DUS16
Dual specificity protein phosphatase 16

1

15

High-throughput

0.618

High

388706

HSPB1
Heat shock protein beta-1

2

7

High-throughput

0.611

High

905073

1433G
14-3-3 protein gamma

2

20

High-throughput

0.611

High

909984

1433E
14-3-3 protein epsilon

2

7

High-throughput

0.611

High

1032947

JIP2
C-Jun-amino-terminal kinase-interacting protein 2

2

4

Small-scale

0.611

High

1191315

KCD20
BTB/POZ domain-containing protein KCTD20

2

1

High-throughput

0.611

High

885608

MLF1
Myeloid leukemia factor 1

2

0

High-throughput

0.585

High

1316237

JIP1
C-Jun-amino-terminal kinase-interacting protein 1

1

2

Small-scale

0.578

High

1071007

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

20

High-throughput

0.541

High

1316192

TRI54
Tripartite motif-containing protein 54

1

9

High-throughput

0.541

High

62788

TBAL3
Tubulin alpha chain-like 3

1

2

High-throughput

0.536

High

128907

P3C2A
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

1

3

High-throughput

0.536

High

151891

IRS4
Insulin receptor substrate 4

1

1

High-throughput

0.536

High

152904

APAF
Apoptotic protease-activating factor 1

1

2

High-throughput

0.536

High

201056

VIP2
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2

1

1

High-throughput

0.536

High

201978

WDR62
WD repeat-containing protein 62

1

3

High-throughput

0.536

High

218063

PEX1
Peroxisomal ATPase PEX1

1

10

High-throughput

0.536

High

237309

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

1

High-throughput

0.536

High

243589

DNJA2
DnaJ homolog subfamily A member 2

1

3

High-throughput

0.536

High

253406

SRGP2
SLIT-ROBO Rho GTPase-activating protein 2

1

2

High-throughput

0.536

High

258180

DNJB6
DnaJ homolog subfamily B member 6

1

3

High-throughput

0.536

High

272268

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

7

High-throughput

0.536

High

272698

OFD1
Centriole and centriolar satellite protein OFD1

1

9

High-throughput

0.536

High

279341

DNJB5
DnaJ homolog subfamily B member 5

1

2

High-throughput

0.536

High

302002

TRI37
E3 ubiquitin-protein ligase TRIM37

1

7

High-throughput

0.536

High

317346

PCNT
Pericentrin

1

7

High-throughput

0.536

High

571769

PFKAL
ATP-dependent 6-phosphofructokinase, liver type

1

2

High-throughput

0.536

High

653362

PYR1
Multifunctional protein CAD

1

3

High-throughput

0.536

High

657647

ITPI2
Protein ITPRID2

1

1

High-throughput

0.536

High

679304

KAP1
cAMP-dependent protein kinase type I-beta regulatory subunit

1

1

High-throughput

0.536

High

679391

KAP3
cAMP-dependent protein kinase type II-beta regulatory subunit

1

1

High-throughput

0.536

High

730347

PRS7
26S proteasome regulatory subunit 7

1

5

High-throughput

0.536

High

782379

KDM5C
Lysine-specific demethylase 5C

1

1

High-throughput

0.536

High

791944

HD
Huntingtin

1

1

High-throughput

0.536

High

807829

MAP1B
Microtubule-associated protein 1B

1

1

High-throughput

0.536

High

835106

TSC2
Tuberin

1

1

High-throughput

0.536

High

840314

PEX5
Peroxisomal targeting signal 1 receptor

1

2

High-throughput

0.536

High

846711

DNA2
DNA replication ATP-dependent helicase/nuclease DNA2

1

2

High-throughput

0.536

High

855726

KIF11
Kinesin-like protein KIF11

1

5

High-throughput

0.536

High

865080

TTC3
E3 ubiquitin-protein ligase TTC3

1

4

High-throughput

0.536

High

915497

ACTA
Actin, aortic smooth muscle

1

18

High-throughput

0.536

High

992310

DPOE1
DNA polymerase epsilon catalytic subunit A

1

3

High-throughput

0.536

High

1000209

IFFO1
Non-homologous end joining factor IFFO1

1

1

High-throughput

0.536

High

1017094

TROP
Trophinin

1

1

High-throughput

0.536

High

1023327

TRI32
E3 ubiquitin-protein ligase TRIM32

1

3

High-throughput

0.536

High

1038315

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

1

11

High-throughput

0.536

High

1040886

MTMR1
Myotubularin-related protein 1

1

2

High-throughput

0.536

High

1049638

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

10

High-throughput

0.536

High

1050449

DPOA2
DNA polymerase alpha subunit B

1

1

High-throughput

0.536

High

1051669

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

2

High-throughput

0.536

High

1056121

NBR1
Next to BRCA1 gene 1 protein

1

1

High-throughput

0.536

High

1056813

ESPL1
Separin

1

1

High-throughput

0.536

High

1064111

TNIP1
TNFAIP3-interacting protein 1

1

6

High-throughput

0.536

High

1102062

ERC6L
DNA excision repair protein ERCC-6-like

1

1

High-throughput

0.536

High

1113841

GRDN
Girdin

1

13

High-throughput

0.536

High

1117596

PLCH1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1

1

3

High-throughput

0.536

High

1121108

GLE1
mRNA export factor GLE1

1

5

High-throughput

0.536

High

1137847

CE350
Centrosome-associated protein 350

1

5

High-throughput

0.536

High

1139086

TASO2
Protein TASOR 2

1

2

High-throughput

0.536

High

1159082

CEP85
Centrosomal protein of 85 kDa

1

11

High-throughput

0.536

High

1159276

PRP8
Pre-mRNA-processing-splicing factor 8

1

3

High-throughput

0.536

High

1161339

VIP1
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1

1

1

High-throughput

0.536

High

1161966

FIGL1
Fidgetin-like protein 1

1

10

High-throughput

0.536

High

1162054

TRI65
E3 ubiquitin-protein ligase TRIM65

1

4

High-throughput

0.536

High

1167971

GGYF2
GRB10-interacting GYF protein 2

1

5

High-throughput

0.536

High

1170142

FA83H
Protein FAM83H

1

1

High-throughput

0.536

High

1173397

STXB4
Syntaxin-binding protein 4

1

2

High-throughput

0.536

High

1173711

VP13C
Intermembrane lipid transfer protein VPS13C

1

2

High-throughput

0.536

High

1200235

N4BP2
NEDD4-binding protein 2

1

1

High-throughput

0.536

High

1201005

LUZP1
Leucine zipper protein 1

1

12

High-throughput

0.536

High

1202453

HOOK3
Protein Hook homolog 3

1

7

High-throughput

0.536

High

1235999

ARFG2
ADP-ribosylation factor GTPase-activating protein 2

1

1

High-throughput

0.536

High

1243683

NAV1
Neuron navigator 1

1

1

High-throughput

0.536

High

1245299

PJA1
E3 ubiquitin-protein ligase Praja-1

1

2

High-throughput

0.536

High

1246024

NEDD1
Protein NEDD1

1

1

High-throughput

0.536

High

1253994

ALMS1
Centrosome-associated protein ALMS1

1

1

High-throughput

0.536

High

1264387

IFT81
Intraflagellar transport protein 81 homolog

1

10

High-throughput

0.536

High

1266668

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

1

High-throughput

0.536

High

1272194

ARHG1
Rho guanine nucleotide exchange factor 1

1

1

High-throughput

0.536

High

1290048

RNF31
E3 ubiquitin-protein ligase RNF31

1

3

High-throughput

0.536

High

1295168

MAGD4
Melanoma-associated antigen D4

1

1

High-throughput

0.536

High

1300712

SPAG5
Sperm-associated antigen 5

1

10

High-throughput

0.536

High

1301480

GCP6
Gamma-tubulin complex component 6

1

1

High-throughput

0.536

High

1301499

GCP5
Gamma-tubulin complex component 5

1

1

High-throughput

0.536

High

1302324

CK5P2
CDK5 regulatory subunit-associated protein 2

1

11

High-throughput

0.536

High

1305500

RGPD5
RANBP2-like and GRIP domain-containing protein 5/6

1

2

High-throughput

0.536

High

1309475

TBA1C
Tubulin alpha-1C chain

1

1

High-throughput

0.536

High

1311120

BTBDA
BTB/POZ domain-containing protein 10

1

1

High-throughput

0.536

High

1312798

TBB6
Tubulin beta-6 chain

1

1

High-throughput

0.536

High

1313664

TBB2B
Tubulin beta-2B chain

1

1

High-throughput

0.536

High

1316193

NUF2
Kinetochore protein Nuf2

1

9

High-throughput

0.536

High

1316194

TRIM4
E3 ubiquitin-protein ligase TRIM4

1

2

High-throughput

0.536

High

1316199

CSTFT
Cleavage stimulation factor subunit 2 tau variant

1

4

High-throughput

0.536

High

1316203

PTN23
Tyrosine-protein phosphatase non-receptor type 23

1

7

High-throughput

0.536

High

1316205

FA83D
Protein FAM83D

1

1

High-throughput

0.536

High

1316206

DHX35
Probable ATP-dependent RNA helicase DHX35

1

1

High-throughput

0.536

High

1316209

JMJD4
2-oxoglutarate and iron-dependent oxygenase JMJD4

1

1

High-throughput

0.536

High

1316210

CENPJ
Centromere protein J

1

7

High-throughput

0.536

High

1316213

ARFG3
ADP-ribosylation factor GTPase-activating protein 3

1

1

High-throughput

0.536

High

1316220

SI1L2
Signal-induced proliferation-associated 1-like protein 2

1

1

High-throughput

0.536

High

1316223

NYNRI
Protein NYNRIN

1

2

High-throughput

0.536

High

1316226

VPS51
Vacuolar protein sorting-associated protein 51 homolog

1

1

High-throughput

0.536

High

1316227

HOOK1
Protein Hook homolog 1

1

7

High-throughput

0.536

High

1316231

BAG5
BAG family molecular chaperone regulator 5

1

1

High-throughput

0.536

High

1316232

AKP8L
A-kinase anchor protein 8-like

1

1

High-throughput

0.536

High

1316233

PZRN3
E3 ubiquitin-protein ligase PDZRN3

1

6

High-throughput

0.536

High

1316234

SMG5
Nonsense-mediated mRNA decay factor SMG5

1

1

High-throughput

0.536

High

1316235

CE164
Centrosomal protein of 164 kDa

1

8

High-throughput

0.536

High

1316240

UBP20
Ubiquitin carboxyl-terminal hydrolase 20

1

7

High-throughput

0.536

High

58489

MEIOC
Meiosis-specific coiled-coil domain-containing protein MEIOC

1

0

High-throughput

0.513

High

64556

ZSWM8
Zinc finger SWIM domain-containing protein 8

1

0

High-throughput

0.513

High

166301

GRRE1
Granule associated Rac and RHOG effector protein 1

1

0

High-throughput

0.513

High

182378

PER1
Period circadian protein homolog 1

1

0

High-throughput

0.513

High

275290

RNH2A
Ribonuclease H2 subunit A

1

0

High-throughput

0.513

High

300962

HAUS5
HAUS augmin-like complex subunit 5

1

0

High-throughput

0.513

High

305196

UBE4B
Ubiquitin conjugation factor E4 B

1

0

High-throughput

0.513

High

308014

ZWINT
ZW10 interactor

1

0

High-throughput

0.513

High

319050

CEP43
Centrosomal protein 43

1

0

High-throughput

0.513

High

327703

ECD
Protein ecdysoneless homolog

1

0

High-throughput

0.513

High

335181

DHE3
Glutamate dehydrogenase 1, mitochondrial

1

0

High-throughput

0.513

High

847890

BRCA2
Breast cancer type 2 susceptibility protein

1

0

High-throughput

0.513

High

869847

PMS1
PMS1 protein homolog 1

1

0

High-throughput

0.513

High

1062392

CND2
Condensin complex subunit 2

1

0

High-throughput

0.513

High

1065417

RB3GP
Rab3 GTPase-activating protein catalytic subunit

1

0

High-throughput

0.513

High

1065996

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

0

High-throughput

0.513

High

1068903

PCM1
Pericentriolar material 1 protein

1

0

High-throughput

0.513

High

1074406

STIL
SCL-interrupting locus protein

1

0

High-throughput

0.513

High

1115670

CCD14
Coiled-coil domain-containing protein 14

1

0

High-throughput

0.513

High

1127773

AMER1
APC membrane recruitment protein 1

1

0

High-throughput

0.513

High

1135888

TUT4
Terminal uridylyltransferase 4

1

0

High-throughput

0.513

High

1139633

DEN4C
DENN domain-containing protein 4C

1

0

High-throughput

0.513

High

1147744

HAUS3
HAUS augmin-like complex subunit 3

1

0

High-throughput

0.513

High

1158393

PMF1
Polyamine-modulated factor 1

1

0

High-throughput

0.513

High

1161451

BORA
Protein aurora borealis

1

0

High-throughput

0.513

High

1163838

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.513

High

1190404

HAUS6
HAUS augmin-like complex subunit 6

1

0

High-throughput

0.513

High

1197931

TEDC1
Tubulin epsilon and delta complex protein 1

1

0

High-throughput

0.513

High

1242001

SMG8
Nonsense-mediated mRNA decay factor SMG8

1

0

High-throughput

0.513

High

1245334

KNL1
Kinetochore scaffold 1

1

0

High-throughput

0.513

High

1256794

RPGF6
Rap guanine nucleotide exchange factor 6

1

0

High-throughput

0.513

High

1256818

SMCR8
Guanine nucleotide exchange protein SMCR8

1

0

High-throughput

0.513

High

1261527

SKA2
Spindle and kinetochore-associated protein 2

1

0

High-throughput

0.513

High

1281157

HPS3
BLOC-2 complex member HPS3

1

0

High-throughput

0.513

High

1281619

RNF34
E3 ubiquitin-protein ligase RNF34

1

0

High-throughput

0.513

High

1287104

HAUS1
HAUS augmin-like complex subunit 1

1

0

High-throughput

0.513

High

1288158

ESS2
Splicing factor ESS-2 homolog

1

0

High-throughput

0.513

High

1295232

SPTCS
Spatacsin

1

0

High-throughput

0.513

High

1297757

FXL18
F-box/LRR-repeat protein 18

1

0

High-throughput

0.513

High

1306915

HAUS7
HAUS augmin-like complex subunit 7

1

0

High-throughput

0.513

High

1311778

HAUS8
HAUS augmin-like complex subunit 8

1

0

High-throughput

0.513

High

1312390

TBCD
Tubulin-specific chaperone D

1

0

High-throughput

0.513

High

1315181

OSB11
Oxysterol-binding protein-related protein 11

1

0

High-throughput

0.513

High

1316195

CE295
Centrosomal protein of 295 kDa

1

0

High-throughput

0.513

High

1316200

APC1
Anaphase-promoting complex subunit 1

1

0

High-throughput

0.513

High

1316201

ASCC2
Activating signal cointegrator 1 complex subunit 2

1

0

High-throughput

0.513

High

1316204

DSN1
Kinetochore-associated protein DSN1 homolog

1

0

High-throughput

0.513

High

1316207

HAUS4
HAUS augmin-like complex subunit 4

1

0

High-throughput

0.513

High

1316211

NCK5L
Nck-associated protein 5-like

1

0

High-throughput

0.513

High

1316214

IFT46
Intraflagellar transport protein 46 homolog

1

0

High-throughput

0.513

High

1316215

4ET
Eukaryotic translation initiation factor 4E transporter

1

0

High-throughput

0.513

High

1316216

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.513

High

1316217

HAUS2
HAUS augmin-like complex subunit 2

1

0

High-throughput

0.513

High

1316228

APC5
Anaphase-promoting complex subunit 5

1

0

High-throughput

0.513

High

1316229

AKA11
A-kinase anchor protein 11

1

0

High-throughput

0.513

High

1316230

CNO11
CCR4-NOT transcription complex subunit 11

1

0

High-throughput

0.513

High

1316236

HPS5
BLOC-2 complex member HPS5

1

0

High-throughput

0.513

High

1316242

LAS1L
Ribosomal biogenesis protein LAS1L

1

0

High-throughput

0.513

High

306303

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

0

High-throughput

0.493

High

118436

HAX1
HCLS1-associated protein X-1

1

4

High-throughput

0.489

High

1015787

KIF1A
Kinesin-like protein KIF1A

1

4

High-throughput

0.489

High

1052604

RCN2
Reticulocalbin-2

1

7

High-throughput

0.489

High

1075867

TRIPB
Thyroid receptor-interacting protein 11

1

8

High-throughput

0.489

High

1121551

EIPR1
EARP and GARP complex-interacting protein 1

1

1

High-throughput

0.489

High

1155874

PHLB3
Pleckstrin homology-like domain family B member 3

1

4

High-throughput

0.489

High

1241735

DYHC2
Cytoplasmic dynein 2 heavy chain 1

1

2

High-throughput

0.489

High

1268555

K0232
Uncharacterized protein KIAA0232

1

1

High-throughput

0.489

High

1286026

ATG2B
Autophagy-related protein 2 homolog B

1

2

High-throughput

0.489

High

1301603

IF140
Intraflagellar transport protein 140 homolog

1

5

High-throughput

0.489

High

1316191

K1671
Uncharacterized protein KIAA1671

1

1

High-throughput

0.489

High

1316197

MFF
Mitochondrial fission factor

1

1

High-throughput

0.489

High

1316222

WDR35
WD repeat-containing protein 35

1

4

High-throughput

0.489

High

1316224

IF172
Intraflagellar transport protein 172 homolog

1

6

High-throughput

0.489

High

118787

AIP
AH receptor-interacting protein

1

4

High-throughput

0.479

High

207994

XPOT
Exportin-T

1

8

High-throughput

0.479

High

636409

DNJB1
DnaJ homolog subfamily B member 1

1

2

High-throughput

0.479

High

647241

1433T
14-3-3 protein theta

1

20

High-throughput

0.479

High

874581

XPO2
Exportin-2

1

4

High-throughput

0.479

High

901736

PFD3
Prefoldin subunit 3

1

3

High-throughput

0.479

High

927484

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.479

High

982450

1433F
14-3-3 protein eta

1

20

High-throughput

0.479

High

1069495

TEBP
Prostaglandin E synthase 3

1

3

High-throughput

0.479

High

1140735

RN123
E3 ubiquitin-protein ligase RNF123

1

1

High-throughput

0.479

High

1316212

Q9HCK3
KIAA1569 protein

1

1

High-throughput

0.479

High

1316238

HIG1A
HIG1 domain family member 1A, mitochondrial

1

1

High-throughput

0.479

High

686055

ARRB2
Beta-arrestin-2

1

0

Small-scale

0.458

High

1145076

WAC2A
WASH complex subunit 2A

1

0

High-throughput

0.458

High

1316196

NXF2
Nuclear RNA export factor 2

1

0

High-throughput

0.458

High

789180

HELZ
Probable helicase with zinc finger domain

1

3

High-throughput

0.445

High

1256609

CE192
Centrosomal protein of 192 kDa

1

1

High-throughput

0.445

High

950698

ARF5
ADP-ribosylation factor 5

1

11

High-throughput

0.437

High

1061740

Q149M6
Exophilin 5

1

1

High-throughput

0.437

High

1243579

EXPH5
Exophilin-5

1

1

High-throughput

0.407

High

949242

COG7
Conserved oligomeric Golgi complex subunit 7

1

0

High-throughput

0.279

Low

1021886

NPRL3
GATOR1 complex protein NPRL3

1

0

High-throughput

0.279

Low

1058875

COG2
Conserved oligomeric Golgi complex subunit 2

1

0

High-throughput

0.279

Low

1101853

SHRM1
Protein Shroom1

1

0

High-throughput

0.279

Low

1132340

SZT2
KICSTOR complex protein SZT2

1

0

High-throughput

0.279

Low

1286325

RUND1
RUN domain-containing protein 1

1

0

High-throughput

0.279

Low

1297635

CC138
Coiled-coil domain-containing protein 138

1

0

High-throughput

0.279

Low

1297902

CE034
Uncharacterized protein C5orf34

1

0

High-throughput

0.279

Low

1311028

NTPCR
Cancer-related nucleoside-triphosphatase

1

0

High-throughput

0.279

Low

1316202

VPS16
Vacuolar protein sorting-associated protein 16 homolog

1

0

High-throughput

0.279

Low

1316208

CS044
Uncharacterized protein C19orf44

1

0

High-throughput

0.279

Low

1316218

SEP10
Septin-10

1

0

High-throughput

0.279

Low

1316219

VPS18
Vacuolar protein sorting-associated protein 18 homolog

1

0

High-throughput

0.279

Low

1316225

ZNHI2
Zinc finger HIT domain-containing protein 2

1

0

High-throughput

0.279

Low

1316241

COG6
Conserved oligomeric Golgi complex subunit 6

1

0

High-throughput

0.279

Low

281870

WFS1
Wolframin

1

0

High-throughput

0.268

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024