Protein: FMNL2
Formin-like protein 2 (Formin homology 2 domain-containing protein 2)

Gene: FMNL2
Organism: Homo sapiens
Interactions: 180
UniProt ID: Q96PY5

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0007010 - cytoskeleton organization
GO:0008360 - regulation of cell shape
GO:0016477 - cell migration
GO:0022604 - regulation of cell morphogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

894328

CDC42
Cell division control protein 42 homolog

2

20

High-throughput

0.793

High

436466

RHOC
Rho-related GTP-binding protein RhoC

2

20

High-throughput

0.754

High

895231

RAB2A
Ras-related protein Rab-2A

2

9

High-throughput

0.754

High

915901

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.754

High

929974

ACTG
Actin, cytoplasmic 2

1

15

High-throughput

0.691

High

1217531

FMNL3
Formin-like protein 3

1

10

High-throughput

0.691

High

120589

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.618

High

349576

RASH
GTPase HRas

1

12

High-throughput

0.618

High

350461

RASK
GTPase KRas

1

19

High-throughput

0.618

High

894794

RAB8A
Ras-related protein Rab-8A

1

4

High-throughput

0.618

High

900815

RHOA
Transforming protein RhoA

1

20

High-throughput

0.618

High

925531

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

1070349

RAB35
Ras-related protein Rab-35

1

9

High-throughput

0.618

High

1299928

FMNL2
Formin-like protein 2

1

10

High-throughput

0.618

High

1299944

RAB6B
Ras-related protein Rab-6B

1

9

High-throughput

0.618

High

1034188

U119A
Protein unc-119 homolog A

2

0

High-throughput

0.602

High

1299932

THIOM
Thioredoxin, mitochondrial

2

1

High-throughput

0.560

High

1299723

SYGP1
Ras/Rap GTPase-activating protein SynGAP

2

2

High-throughput

0.552

High

865075

TTC3
E3 ubiquitin-protein ligase TTC3

1

4

High-throughput

0.541

High

428619

INVO
Involucrin

1

2

High-throughput

0.536

High

430307

PROF1
Profilin-1

1

11

High-throughput

0.536

High

820366

SPB4
Serpin B4

1

1

High-throughput

0.536

High

1197651

S1A7A
Protein S100-A7A

1

3

High-throughput

0.536

High

1200169

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

1

High-throughput

0.536

High

1242281

PNMA1
Paraneoplastic antigen Ma1

2

1

High-throughput

0.533

High

819662

NRIP1
Nuclear receptor-interacting protein 1

1

0

High-throughput

0.518

High

239197

CTND1
Catenin delta-1

1

3

High-throughput

0.515

High

716751

CTNA1
Catenin alpha-1

1

1

High-throughput

0.515

High

1052289

SRC8
Src substrate cortactin

1

2

High-throughput

0.515

High

1087350

H2B2E
Histone H2B type 2-E

1

1

High-throughput

0.515

High

1183100

MARK2
Serine/threonine-protein kinase MARK2

1

2

High-throughput

0.515

High

1299947

RAI14
Ankycorbin

1

5

High-throughput

0.515

High

1299960

MRCKB
Serine/threonine-protein kinase MRCK beta

1

6

High-throughput

0.515

High

299785

PLPHP
Pyridoxal phosphate homeostasis protein

1

0

High-throughput

0.513

High

1261796

POF1B
Protein POF1B

1

0

High-throughput

0.513

High

263795

PR40A
Pre-mRNA-processing factor 40 homolog A

1

12

High-throughput

0.508

High

395538

A4
Amyloid-beta precursor protein

1

3

High-throughput

0.501

High

344325

AACT
Alpha-1-antichymotrypsin

1

1

High-throughput

0.489

High

857930

CRIP2
Cysteine-rich protein 2

1

2

High-throughput

0.489

High

945718

NGAL
Neutrophil gelatinase-associated lipocalin

1

2

High-throughput

0.489

High

1262275

SPRY4
SPRY domain-containing protein 4

1

3

High-throughput

0.489

High

1285053

ARRD3
Arrestin domain-containing protein 3

1

1

High-throughput

0.489

High

925979

AP2B1
AP-2 complex subunit beta

1

5

High-throughput

0.481

High

1014067

AP1B1
AP-1 complex subunit beta-1

1

3

High-throughput

0.481

High

1189634

K1C27
Keratin, type I cytoskeletal 27

1

1

High-throughput

0.481

High

1238233

NECA1
N-terminal EF-hand calcium-binding protein 1

1

1

High-throughput

0.481

High

135485

PPP6
Serine/threonine-protein phosphatase 6 catalytic subunit

1

3

High-throughput

0.479

High

204723

E41L2
Band 4.1-like protein 2

1

5

High-throughput

0.479

High

228411

PRKN
E3 ubiquitin-protein ligase parkin

1

6

High-throughput

0.479

High

240432

SNX2
Sorting nexin-2

1

3

High-throughput

0.479

High

253397

SRGP2
SLIT-ROBO Rho GTPase-activating protein 2

1

5

High-throughput

0.479

High

320391

SNP29
Synaptosomal-associated protein 29

1

1

High-throughput

0.479

High

374720

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

8

High-throughput

0.479

High

403946

ITB1
Integrin beta-1

1

4

High-throughput

0.479

High

433952

LYN
Tyrosine-protein kinase Lyn

1

13

High-throughput

0.479

High

505669

EPB41
Protein 4.1

1

5

High-throughput

0.479

High

522141

CADH1
Cadherin-1

1

3

High-throughput

0.479

High

533331

PLST
Plastin-3

1

2

High-throughput

0.479

High

542419

PLAK
Junction plakoglobin

1

3

High-throughput

0.479

High

647949

MARK3
MAP/microtubule affinity-regulating kinase 3

1

2

High-throughput

0.479

High

714569

GRK5
G protein-coupled receptor kinase 5

1

1

High-throughput

0.479

High

717291

CTNB1
Catenin beta-1

1

2

High-throughput

0.479

High

725992

ADDA
Alpha-adducin

1

2

High-throughput

0.479

High

833645

NUMB
Protein numb homolog

1

1

High-throughput

0.479

High

876472

AFAD
Afadin

1

8

High-throughput

0.479

High

913054

ARF6
ADP-ribosylation factor 6

1

1

High-throughput

0.479

High

926247

VAMP2
Vesicle-associated membrane protein 2

1

3

High-throughput

0.479

High

973789

AKA12
A-kinase anchor protein 12

1

1

High-throughput

0.479

High

984649

CALD1
Caldesmon

1

10

High-throughput

0.479

High

1020208

PTN13
Tyrosine-protein phosphatase non-receptor type 13

1

6

High-throughput

0.479

High

1021553

DLG1
Disks large homolog 1

1

1

High-throughput

0.479

High

1035398

GAB1
GRB2-associated-binding protein 1

1

2

High-throughput

0.479

High

1036464

PICAL
Phosphatidylinositol-binding clathrin assembly protein

1

1

High-throughput

0.479

High

1040505

SNX1
Sorting nexin-1

1

3

High-throughput

0.479

High

1047797

CKAP5
Cytoskeleton-associated protein 5

1

1

High-throughput

0.479

High

1050033

SCRIB
Protein scribble homolog

1

1

High-throughput

0.479

High

1063173

SEPT2
Septin-2

1

2

High-throughput

0.479

High

1071561

L2GL1
Lethal(2) giant larvae protein homolog 1

1

1

High-throughput

0.479

High

1079409

VAMP3
Vesicle-associated membrane protein 3

1

2

High-throughput

0.479

High

1080972

SEPT7
Septin-7

1

2

High-throughput

0.479

High

1113831

GRDN
Girdin

1

5

High-throughput

0.479

High

1137897

MRCKA
Serine/threonine-protein kinase MRCK alpha

1

2

High-throughput

0.479

High

1140715

RN123
E3 ubiquitin-protein ligase RNF123

1

4

High-throughput

0.479

High

1187723

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

6

High-throughput

0.479

High

1190240

NPHP3
Nephrocystin-3

1

2

High-throughput

0.479

High

1203011

LIPB1
Liprin-beta-1

1

5

High-throughput

0.479

High

1237876

ENAH
Protein enabled homolog

1

8

High-throughput

0.479

High

1253530

CIP2A
Protein CIP2A

1

3

High-throughput

0.479

High

1268492

ANS1A
Ankyrin repeat and SAM domain-containing protein 1A

1

3

High-throughput

0.479

High

1269116

NECT2
Nectin-2

1

2

High-throughput

0.479

High

1271863

NEO1
Neogenin

1

1

High-throughput

0.479

High

1281325

FBXW7
F-box/WD repeat-containing protein 7

1

1

High-throughput

0.479

High

1299929

RUFY1
RUN and FYVE domain-containing protein 1

1

6

High-throughput

0.479

High

1299930

MMS19
MMS19 nucleotide excision repair protein homolog

1

2

High-throughput

0.479

High

1299933

SH3G1
Endophilin-A2

1

4

High-throughput

0.479

High

1299938

PKHA1
Pleckstrin homology domain-containing family A member 1

1

2

High-throughput

0.479

High

1299939

E41L5
Band 4.1-like protein 5

1

5

High-throughput

0.479

High

1299940

WDR6
tRNA

1

3

High-throughput

0.479

High

1299941

BRD7
Bromodomain-containing protein 7

1

1

High-throughput

0.479

High

1299945

CHMP5
Charged multivesicular body protein 5

1

1

High-throughput

0.479

High

1299948

EP15R
Epidermal growth factor receptor substrate 15-like 1

1

1

High-throughput

0.479

High

1299949

ADDG
Gamma-adducin

1

2

High-throughput

0.479

High

1299950

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

1299951

SEPT9
Septin-9

1

2

High-throughput

0.479

High

1299952

BI2L1
BAR/IMD domain-containing adapter protein 2-like 1

1

5

High-throughput

0.479

High

1299953

DBNL
Drebrin-like protein

1

3

High-throughput

0.479

High

1299954

KDIS
Kinase D-interacting substrate of 220 kDa

1

2

High-throughput

0.479

High

1299955

BAIP2
BAR/IMD domain-containing adapter protein 2

1

3

High-throughput

0.479

High

1299956

CHM2B
Charged multivesicular body protein 2b

1

1

High-throughput

0.479

High

1299958

E41L3
Band 4.1-like protein 3

1

5

High-throughput

0.479

High

1299959

CIA2B
Cytosolic iron-sulfur assembly component 2B

1

1

High-throughput

0.479

High

1299961

SNX9
Sorting nexin-9

1

5

High-throughput

0.479

High

1299962

SNX5
Sorting nexin-5

1

3

High-throughput

0.479

High

1299963

SAR1B
Small COPII coat GTPase SAR1B

1

2

High-throughput

0.479

High

180917

YKT6
Synaptobrevin homolog YKT6

1

0

High-throughput

0.458

High

437447

4F2
Amino acid transporter heavy chain SLC3A2

1

0

High-throughput

0.458

High

823283

MRP
MARCKS-related protein

1

0

High-throughput

0.458

High

841296

CDK7
Cyclin-dependent kinase 7

1

0

High-throughput

0.458

High

959613

VIGLN
Vigilin

1

0

High-throughput

0.458

High

1057089

EPN4
Clathrin interactor 1

1

0

High-throughput

0.458

High

1117427

TB10B
TBC1 domain family member 10B

1

0

High-throughput

0.458

High

1126029

PP6R3
Serine/threonine-protein phosphatase 6 regulatory subunit 3

1

0

High-throughput

0.458

High

1259830

ZC3HF
Zinc finger CCCH domain-containing protein 15

1

0

High-throughput

0.458

High

1267697

NDRG1
Protein NDRG1

1

0

High-throughput

0.458

High

1274105

STMN2
Stathmin-2

1

0

High-throughput

0.458

High

1283787

FERM2
Fermitin family homolog 2

1

0

High-throughput

0.458

High

1298503

DOCK7
Dedicator of cytokinesis protein 7

1

0

High-throughput

0.458

High

1299931

NIBA2
Protein Niban 2

1

0

High-throughput

0.458

High

1299937

KT3K
Ketosamine-3-kinase

1

0

High-throughput

0.458

High

989067

FMR1
Fragile X messenger ribonucleoprotein 1

1

2

High-throughput

0.457

High

965140

ANK2
Ankyrin-2

1

2

High-throughput

0.445

High

1153340

PKHA7
Pleckstrin homology domain-containing family A member 7

1

10

High-throughput

0.445

High

849806

SUOX
Sulfite oxidase, mitochondrial

1

2

High-throughput

0.439

High

1254161

MIPO1
Mirror-image polydactyly gene 1 protein

1

1

High-throughput

0.439

High

500861

CLUS
Clusterin

1

0

High-throughput

0.438

High

1299943

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.438

High

72330

B3KVV6
cDNA FLJ41607 fis, clone CTONG3001370, highly similar to Homo sapiens alpha-2-macroglobulin-like 1

1

1

High-throughput

0.437

High

118068

SNP23
Synaptosomal-associated protein 23

1

1

High-throughput

0.437

High

233592

NUPR1
Nuclear protein 1

1

1

High-throughput

0.437

High

279677

FLOT1
Flotillin-1

1

2

High-throughput

0.437

High

282999

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

3

High-throughput

0.437

High

324866

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

1

3

High-throughput

0.437

High

347637

MYC
Myc proto-oncogene protein

1

4

High-throughput

0.437

High

385370

NTRK1
High affinity nerve growth factor receptor

1

5

High-throughput

0.437

High

514886

MPRI
Cation-independent mannose-6-phosphate receptor

1

1

High-throughput

0.437

High

734528

ARL3
ADP-ribosylation factor-like protein 3

1

6

High-throughput

0.437

High

793431

MUC18
Cell surface glycoprotein MUC18

1

5

High-throughput

0.437

High

940531

CXAR
Coxsackievirus and adenovirus receptor

1

4

High-throughput

0.437

High

980512

NOTC2
Neurogenic locus notch homolog protein 2

1

1

High-throughput

0.437

High

1048647

DSG2
Desmoglein-2

1

4

High-throughput

0.437

High

1067103

BRD3
Bromodomain-containing protein 3

1

3

High-throughput

0.437

High

1114196

TBB8
Tubulin beta-8 chain

1

1

High-throughput

0.437

High

1152047

LTOR1
Ragulator complex protein LAMTOR1

1

3

High-throughput

0.437

High

1171307

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.437

High

1187559

GRIN1
G protein-regulated inducer of neurite outgrowth 1

1

2

High-throughput

0.437

High

1224468

UNC5B
Netrin receptor UNC5B

1

1

High-throughput

0.437

High

1230337

CXD3
Gap junction delta-3 protein

1

2

High-throughput

0.437

High

1299935

SIK2
Serine/threonine-protein kinase SIK2

1

2

Small-scale

0.437

High

1299942

NECT3
Nectin-3

1

2

High-throughput

0.437

High

1299957

LAMP3
Lysosome-associated membrane glycoprotein 3

1

4

High-throughput

0.437

High

1299965

ROBO1
Roundabout homolog 1

1

1

High-throughput

0.437

High

66425

A2ML1
Alpha-2-macroglobulin-like protein 1

1

1

High-throughput

0.407

High

1072805

TOM20
Mitochondrial import receptor subunit TOM20 homolog

1

2

High-throughput

0.407

High

1233155

RYBP
RING1 and YY1-binding protein

1

1

High-throughput

0.407

High

878145

PKNX1
Homeobox protein PKNOX1

1

0

High-throughput

0.282

High

1295462

LCOR
Ligand-dependent corepressor

1

0

High-throughput

0.282

High

646442

KAD4
Adenylate kinase 4, mitochondrial

1

0

High-throughput

0.279

Low

1243643

DR9C7
Short-chain dehydrogenase/reductase family 9C member 7

1

0

High-throughput

0.279

Low

1223913

PHAR4
Phosphatase and actin regulator 4

1

0

High-throughput

0.269

Low

708248

ERD22
ER lumen protein-retaining receptor 2

1

0

High-throughput

0.249

Low

1120303

CEP55
Centrosomal protein of 55 kDa

1

0

High-throughput

0.249

Low

1190355

HDDC2
5'-deoxynucleotidase HDDC2

1

0

High-throughput

0.249

Low

1191954

ARPIN
Arpin

1

0

High-throughput

0.249

Low

1203977

LSR
Lipolysis-stimulated lipoprotein receptor

1

0

High-throughput

0.249

Low

1242826

CNNM3
Metal transporter CNNM3

1

0

High-throughput

0.249

Low

1299934

ESYT1
Extended synaptotagmin-1

1

0

High-throughput

0.249

Low

1299936

S6A15
Sodium-dependent neutral amino acid transporter B(0)AT2

1

0

High-throughput

0.249

Low

1299946

HACD3
Very-long-chain

1

0

High-throughput

0.249

Low

1299964

S4A7
Sodium bicarbonate cotransporter 3

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024