Protein: ZDH12
Palmitoyltransferase ZDHHC12 (EC 2.3.1.225) (DHHC domain-containing cysteine-rich protein 12) (DHHC-12) (Zinc finger DHHC domain-containing protein 12) (Zinc finger protein 400)

Gene: ZDH12, ZDHHC12
Organism: Homo sapiens
Interactions: 125
UniProt ID: Q96GR4

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005794 - Golgi apparatus
GO:0006612 - protein targeting to membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

155494

C2C2L
Phospholipid transfer protein C2CD2L

1

1

High-throughput

0.536

High

171555

S27A2
Long-chain fatty acid transport protein 2

1

3

High-throughput

0.536

High

243822

ADCY3
Adenylate cyclase type 3

1

2

High-throughput

0.536

High

297069

DHRS3
Short-chain dehydrogenase/reductase 3

1

2

High-throughput

0.536

High

857532

NOTC1
Neurogenic locus notch homolog protein 1

1

6

High-throughput

0.536

High

1085364

SCAP
Sterol regulatory element-binding protein cleavage-activating protein

1

4

High-throughput

0.536

High

1103570

PDE3B
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B

1

2

High-throughput

0.536

High

1111657

STIM1
Stromal interaction molecule 1

1

1

High-throughput

0.536

High

1164152

CP51A
Lanosterol 14-alpha demethylase

1

1

High-throughput

0.536

High

1207890

S27A3
Long-chain fatty acid transport protein 3

1

3

High-throughput

0.536

High

1208112

RNFT1
E3 ubiquitin-protein ligase RNFT1

1

7

High-throughput

0.536

High

1240933

S27A4
Long-chain fatty acid transport protein 4

1

3

High-throughput

0.536

High

1243651

S27A1
Long-chain fatty acid transport protein 1

1

3

High-throughput

0.536

High

1277733

TMC6
Transmembrane channel-like protein 6

1

1

High-throughput

0.536

High

1287410

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

8

High-throughput

0.536

High

1294809

STX12
Syntaxin-12

1

8

High-throughput

0.536

High

1333108

AT11C
Phospholipid-transporting ATPase IG

1

1

High-throughput

0.536

High

1334507

RN149
E3 ubiquitin-protein ligase RNF149

1

10

High-throughput

0.536

High

1348297

GOGA5
Golgin subfamily A member 5

1

2

High-throughput

0.536

High

1353405

UBP33
Ubiquitin carboxyl-terminal hydrolase 33

1

2

High-throughput

0.536

High

1392283

PMYT1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase

1

4

High-throughput

0.536

High

1392286

CIB1
Calcium and integrin-binding protein 1

1

2

High-throughput

0.536

High

1392287

ATF6B
Cyclic AMP-dependent transcription factor ATF-6 beta

1

4

High-throughput

0.536

High

1392290

ESYT1
Extended synaptotagmin-1

1

5

High-throughput

0.536

High

1392296

ELOV4
Very long chain fatty acid elongase 4

1

1

High-throughput

0.536

High

1392297

LMA2L
VIP36-like protein

1

1

High-throughput

0.536

High

1392302

SEC12
Guanine nucleotide-exchange factor SEC12

1

1

High-throughput

0.536

High

1392308

STIM2
Stromal interaction molecule 2

1

1

High-throughput

0.536

High

1392312

AMFR
E3 ubiquitin-protein ligase AMFR

1

4

High-throughput

0.536

High

1392314

FND3A
Fibronectin type-III domain-containing protein 3A

1

3

High-throughput

0.536

High

1392316

DHRS7
Dehydrogenase/reductase SDR family member 7

1

1

High-throughput

0.536

High

1392318

BACE2
Beta-secretase 2

1

2

High-throughput

0.536

High

60394

NBAS
NBAS subunit of NRZ tethering complex

1

0

High-throughput

0.513

High

139109

FAAH1
Fatty-acid amide hydrolase 1

1

0

High-throughput

0.513

High

161151

ABCD4
Lysosomal cobalamin transporter ABCD4

1

0

High-throughput

0.513

High

185028

SPTC2
Serine palmitoyltransferase 2

1

0

High-throughput

0.513

High

247532

FZD6
Frizzled-6

1

0

High-throughput

0.513

High

248614

FADS1
Acyl-CoA

1

0

High-throughput

0.513

High

261249

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.513

High

316552

B3GA3
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3

1

0

High-throughput

0.513

High

790170

PIGA
Phosphatidylinositol N-acetylglucosaminyltransferase subunit A

1

0

High-throughput

0.513

High

1085157

TMM94
Transmembrane protein 94

1

0

High-throughput

0.513

High

1091966

SEC20
Vesicle transport protein SEC20

1

0

High-throughput

0.513

High

1105542

OS9
Protein OS-9

1

0

High-throughput

0.513

High

1127854

ERG1
Squalene monooxygenase

1

0

High-throughput

0.513

High

1238362

RETST
All-trans-retinol 13,14-reductase

1

0

High-throughput

0.513

High

1260351

ANO5
Anoctamin-5

1

0

High-throughput

0.513

High

1275392

ERMP1
Endoplasmic reticulum metallopeptidase 1

1

0

High-throughput

0.513

High

1276273

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.513

High

1288645

GPAT4
Glycerol-3-phosphate acyltransferase 4

1

0

High-throughput

0.513

High

1293981

ANKL2
Ankyrin repeat and LEM domain-containing protein 2

1

0

High-throughput

0.513

High

1324302

GHDC
GH3 domain-containing protein

1

0

High-throughput

0.513

High

1331815

NAT8L
N-acetylaspartate synthetase

1

0

High-throughput

0.513

High

1337632

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.513

High

1353079

PIGO
GPI ethanolamine phosphate transferase 3, catalytic subunit

1

0

High-throughput

0.513

High

1362075

PMGT1
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1

1

0

High-throughput

0.513

High

1369292

EDA
Ectodysplasin-A

1

0

High-throughput

0.513

High

1383299

VTI1A
Vesicle transport through interaction with t-SNAREs homolog 1A

1

0

High-throughput

0.513

High

1386172

ASTRA
Protein Aster-A

1

0

High-throughput

0.513

High

1388344

NGBR
Dehydrodolichyl diphosphate synthase complex subunit NUS1

1

0

High-throughput

0.513

High

1392284

CGRF1
Cell growth regulator with RING finger domain protein 1

1

0

High-throughput

0.513

High

1392289

PIGQ
Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q

1

0

High-throughput

0.513

High

1392292

CA043
Protein C1orf43

1

0

High-throughput

0.513

High

1392295

OSBL8
Oxysterol-binding protein-related protein 8

1

0

High-throughput

0.513

High

1392298

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.513

High

1392306

TM39A
Transmembrane protein 39A

1

0

High-throughput

0.513

High

1392320

POMT1
Protein O-mannosyl-transferase 1

1

0

High-throughput

0.513

High

704548

RXRB
Retinoic acid receptor RXR-beta

1

3

High-throughput

0.494

High

175413

PLXB2
Plexin-B2

1

3

High-throughput

0.489

High

189772

STX7
Syntaxin-7

1

8

High-throughput

0.489

High

250133

ADCY9
Adenylate cyclase type 9

1

3

High-throughput

0.489

High

320486

TM63A
Mechanosensitive cation channel TMEM63A

1

3

High-throughput

0.489

High

321777

AGRL1
Adhesion G protein-coupled receptor L1

1

2

High-throughput

0.489

High

349531

TSN15
Tetraspanin-15

1

13

High-throughput

0.489

High

560991

GP1BB
Platelet glycoprotein Ib beta chain

1

1

High-throughput

0.489

High

787331

ACV1B
Activin receptor type-1B

1

1

High-throughput

0.489

High

908311

ADCY7
Adenylate cyclase type 7

1

2

High-throughput

0.489

High

933462

S12A2
Solute carrier family 12 member 2

1

4

High-throughput

0.489

High

1034967

GCYB1
Guanylate cyclase soluble subunit beta-1

1

3

High-throughput

0.489

High

1121139

UBE4A
Ubiquitin conjugation factor E4 A

1

1

High-throughput

0.489

High

1198267

FND3B
Fibronectin type III domain-containing protein 3B

1

3

High-throughput

0.489

High

1212283

TM63B
Mechanosensitive cation channel TMEM63B

1

3

High-throughput

0.489

High

1212497

MRP7
ATP-binding cassette sub-family C member 10

1

1

High-throughput

0.489

High

1248253

KCNT2
Potassium channel subfamily T member 2

1

4

High-throughput

0.489

High

1248389

I27RA
Interleukin-27 receptor subunit alpha

1

7

High-throughput

0.489

High

1278306

LRP10
Low-density lipoprotein receptor-related protein 10

1

4

High-throughput

0.489

High

1309759

CTL2
Choline transporter-like protein 2

1

1

High-throughput

0.489

High

1310835

LRC8A
Volume-regulated anion channel subunit LRRC8A

1

1

High-throughput

0.489

High

1314529

TM192
Transmembrane protein 192

1

1

High-throughput

0.489

High

1335148

LEMD2
LEM domain-containing protein 2

1

1

High-throughput

0.489

High

1384177

TM186
Transmembrane protein 186

1

2

High-throughput

0.489

High

1392285

ABCA3
Phospholipid-transporting ATPase ABCA3

1

2

High-throughput

0.489

High

1392293

S12A9
Solute carrier family 12 member 9

1

8

High-throughput

0.489

High

1392294

ABCA2
ATP-binding cassette sub-family A member 2

1

1

High-throughput

0.489

High

1392299

SNX25
Sorting nexin-25

1

1

High-throughput

0.489

High

1392300

PCX3
Pecanex-like protein 3

1

2

High-throughput

0.489

High

1392301

AT133
Polyamine-transporting ATPase 13A3

1

3

High-throughput

0.489

High

1392303

AT132
Polyamine-transporting ATPase 13A2

1

3

High-throughput

0.489

High

1392305

SEM4G
Semaphorin-4G

1

4

High-throughput

0.489

High

1392307

TYW1
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1

1

1

High-throughput

0.489

High

1392309

FA8A1
Protein FAM8A1

1

2

High-throughput

0.489

High

1392310

S12A6
Solute carrier family 12 member 6

1

7

High-throughput

0.489

High

1392311

KCNG1
Voltage-gated potassium channel regulatory subunit KCNG1

1

3

High-throughput

0.489

High

1392313

S12A4
Solute carrier family 12 member 4

1

9

High-throughput

0.489

High

1392315

MAN1
Inner nuclear membrane protein Man1

1

2

High-throughput

0.489

High

1392317

SNX14
Sorting nexin-14

1

3

High-throughput

0.489

High

1392319

S12A7
Solute carrier family 12 member 7

1

8

High-throughput

0.489

High

814842

CUX1
Homeobox protein cut-like 1

1

4

High-throughput

0.479

High

1392282

NLRP3
NACHT, LRR and PYD domains-containing protein 3

1

1

Small-scale

0.479

High

1392281

ABHD8
Protein ABHD8

1

0

Small-scale

0.458

High

1119454

CASP
Protein CASP

1

6

High-throughput

0.445

High

1211079

PR15B
Protein phosphatase 1 regulatory subunit 15B

1

0

High-throughput

0.426

High

341348

ECEL1
Endothelin-converting enzyme-like 1

1

0

High-throughput

0.279

Low

1010515

EREP3
Protein ENTREP3

1

0

High-throughput

0.279

Low

1187187

IPIL2
Inositol 1,4,5-trisphosphate receptor-interacting protein-like 2

1

0

High-throughput

0.279

Low

1209986

TM201
Transmembrane protein 201

1

0

High-throughput

0.279

Low

1279532

ADCK2
Uncharacterized aarF domain-containing protein kinase 2

1

0

High-throughput

0.279

Low

1335565

DGLB
Diacylglycerol lipase-beta

1

0

High-throughput

0.279

Low

1357307

THEM6
Protein THEM6

1

0

High-throughput

0.279

Low

1357934

DCAKD
Dephospho-CoA kinase domain-containing protein

1

0

High-throughput

0.279

Low

1369917

MRP2
ATP-binding cassette sub-family C member 2

1

0

High-throughput

0.279

Low

1392280

S41A3
Solute carrier family 41 member 3

1

0

High-throughput

0.279

Low

1392288

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

1

0

High-throughput

0.279

Low

1392291

TMM70
Transmembrane protein 70, mitochondrial

1

0

High-throughput

0.279

Low

1392304

CNNM1
Metal transporter CNNM1

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025