Protein: IF2A
Eukaryotic translation initiation factor 2 subunit 1 (Eukaryotic translation initiation factor 2 subunit alpha) (eIF-2-alpha) (eIF-2A) (eIF-2alpha) (eIF2-alpha)

Gene: IF2A, eIF2alpha
Organism: Drosophila melanogaster
Interactions: 22
UniProt ID: P41374

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0003743 - translation initiation factor activity
GO:0005829 - cytosol
GO:0005850 - eukaryotic translation initiation factor 2 complex
GO:0005851 - eukaryotic translation initiation factor 2B complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

834814

IF2G
Eukaryotic translation initiation factor 2 subunit 3

1

7

High-throughput

0.621

High

834817

AKT1
RAC serine/threonine-protein kinase

1

1

High-throughput

0.618

High

834825

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

1

High-throughput

0.618

High

834830

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

3

High-throughput

0.618

High

834822

E2AK3
Eukaryotic translation initiation factor 2-alpha kinase

1

17

Small-scale

0.579

High

834818

Q8T9L5
Serine/threonine-protein kinase STK11

1

2

High-throughput

0.553

High

834815

DIAP2
Death-associated inhibitor of apoptosis 2

1

1

High-throughput

0.479

High

834824

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

1

High-throughput

0.479

High

834828

RHEB
GTP-binding protein Rheb homolog

1

2

High-throughput

0.479

High

834829

PGPLE
Peptidoglycan-recognition protein LE

1

1

High-throughput

0.479

High

834831

Q9XYZ6
Peptidyl-prolyl cis-trans isomerase

1

5

High-throughput

0.464

High

834819

NFKB1
Nuclear factor NF-kappa-B p110 subunit

1

0

High-throughput

0.458

High

834821

NEMO
NF-kappa-B essential modulator

1

0

High-throughput

0.458

High

834823

FADD
Fas-associated death domain protein

1

0

High-throughput

0.458

High

356728

CHDM
Chromodomain-helicase-DNA-binding protein Mi-2 homolog

1

7

High-throughput

0.445

High

834820

PGPLC
Peptidoglycan-recognition protein LC

1

1

High-throughput

0.437

High

834812

SUV39
Histone-lysine N-methyltransferase Su(var)3-9

1

5

High-throughput

0.417

High

68903

MBD56
Methyl-CpG-binding domain protein 5/6 homolog sba

1

0

High-throughput

0.249

Low

834813

Q0KIA5
FI01140p1

1

0

High-throughput

0.249

Low

834816

Q6NQZ7
LD40663p

1

0

High-throughput

0.249

Low

834826

ZUC
Mitochondrial cardiolipin hydrolase

1

0

High-throughput

0.249

Low

834827

ORCO
Odorant receptor coreceptor

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025