Protein: COMP
Cartilage oligomeric matrix protein (COMP) (Thrombospondin-5) (TSP5)

Gene: COMP
Organism: Homo sapiens
Interactions: 23
UniProt ID: P49747

Gene Ontology (top 5):
GO:0001501 - skeletal system development
GO:0002020 - protease binding
GO:0002063 - chondrocyte development
GO:0003417 - growth plate cartilage development
GO:0005178 - integrin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

133006

MATN2
Matrilin-2

1

20

High-throughput

0.691

High

183388

MATN3
Matrilin-3

1

20

Small-scale

0.647

High

733104

OTX1
Homeobox protein OTX1

4

5

High-throughput

0.637

High

70145

CRTP1
Cysteine-rich tail protein 1

2

1

High-throughput

0.606

High

715879

AQP1
Aquaporin-1

2

1

High-throughput

0.606

High

888500

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

2

9

High-throughput

0.606

High

888495

ATS12
A disintegrin and metalloproteinase with thrombospondin motifs 12

2

13

Small-scale

0.601

High

128567

ATOX1
Copper transport protein ATOX1

2

0

High-throughput

0.580

High

888499

NUFP2
FMR1-interacting protein NUFIP2

2

6

High-throughput

0.553

High

822531

VHL
von Hippel-Lindau disease tumor suppressor

1

0

High-throughput

0.493

High

888494

MEOX2
Homeobox protein MOX-2

1

7

High-throughput

0.481

High

872072

SOX2
Transcription factor SOX-2

1

5

High-throughput

0.479

High

888498

Q6FHY5
MEOX2 protein

1

9

High-throughput

0.470

High

452200

PDIA1
Protein disulfide-isomerase

1

5

Small-scale

0.445

High

534790

BIP
Endoplasmic reticulum chaperone BiP

1

4

Small-scale

0.445

High

566594

PDIA4
Protein disulfide-isomerase A4

1

5

Small-scale

0.445

High

573386

ENPL
Endoplasmin

1

3

Small-scale

0.445

High

656076

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

2

Small-scale

0.445

High

888497

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

2

Small-scale

0.445

High

888501

ATS7
A disintegrin and metalloproteinase with thrombospondin motifs 7

1

13

Small-scale

0.445

High

888502

HYOU1
Hypoxia up-regulated protein 1

1

2

Small-scale

0.445

High

888496

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.437

High

827702

STAT3
Signal transducer and activator of transcription 3

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025