Protein: OBI1
ORC ubiquitin ligase 1 (OBI1) (EC 2.3.2.27) (RING finger protein 219)

Gene: OBI1
Organism: Homo sapiens
Interactions: 149
UniProt ID: Q5W0B1

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0003682 - chromatin binding
GO:0004842 - ubiquitin-protein transferase activity
GO:0006275 - regulation of DNA replication
GO:0006513 - protein monoubiquitination

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1139822

OBI1
ORC ubiquitin ligase 1

2

0

Small-scale

0.738

High

849339

UB2D1
Ubiquitin-conjugating enzyme E2 D1

1

1

Small-scale

0.647

High

919749

UB2D2
Ubiquitin-conjugating enzyme E2 D2

1

1

Small-scale

0.647

High

908687

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.618

High

1139860

CNO6L
CCR4-NOT transcription complex subunit 6-like

2

1

High-throughput

0.611

High

1139881

CNOT2
CCR4-NOT transcription complex subunit 2

3

1

Small-scale

0.606

High

257365

CNOT3
CCR4-NOT transcription complex subunit 3

3

2

Small-scale

0.603

High

1139888

CNOT7
CCR4-NOT transcription complex subunit 7

2

1

Small-scale

0.595

High

1041777

CUL3
Cullin-3

2

0

High-throughput

0.585

High

1136120

RC3H1
Roquin-1

2

1

Small-scale

0.584

High

244561

BRD4
Bromodomain-containing protein 4

2

1

High-throughput

0.576

High

217267

ORC5
Origin recognition complex subunit 5

1

1

Small-scale

0.561

High

1139890

AGO2
Protein argonaute-2

2

0

High-throughput

0.559

High

1139883

ORC3
Origin recognition complex subunit 3

1

0

Small-scale

0.537

High

1139832

GLT12
Polypeptide N-acetylgalactosaminyltransferase 12

1

1

High-throughput

0.536

High

1139879

GALT9
Polypeptide N-acetylgalactosaminyltransferase 9

1

1

High-throughput

0.536

High

1139870

TB182
182 kDa tankyrase-1-binding protein

2

1

High-throughput

0.533

High

241557

H2B1K
Histone H2B type 1-K

1

0

High-throughput

0.517

High

877620

FOXG1
Forkhead box protein G1

1

0

High-throughput

0.513

High

996100

HDHD1
Pseudouridine-5'-phosphatase

1

0

High-throughput

0.513

High

1128323

SOLH1
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1

1

0

High-throughput

0.513

High

1139823

CNDH2
Condensin-2 complex subunit H2

1

0

High-throughput

0.513

High

1139831

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1139867

NPAS1
Neuronal PAS domain-containing protein 1

1

0

High-throughput

0.513

High

1139869

TX13A
Testis-expressed protein 13A

1

0

High-throughput

0.513

High

1139872

RPP21
Ribonuclease P protein subunit p21

1

0

High-throughput

0.513

High

1139892

CNOT6
CCR4-NOT transcription complex subunit 6

1

1

Small-scale

0.501

High

258066

DNJB6
DnaJ homolog subfamily B member 6

1

1

High-throughput

0.489

High

1139843

DNJB8
DnaJ homolog subfamily B member 8

1

1

High-throughput

0.489

High

1139854

HDA11
Histone deacetylase 11

1

1

High-throughput

0.489

High

1139866

DNJC7
DnaJ homolog subfamily C member 7

1

1

High-throughput

0.489

High

942724

SRPK2
SRSF protein kinase 2

1

0

High-throughput

0.480

High

1123370

BRDT
Bromodomain testis-specific protein

1

1

High-throughput

0.479

High

1139855

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

1

Small-scale

0.479

High

1139877

RC3H2
Roquin-2

1

2

High-throughput

0.479

High

1139886

CNOT8
CCR4-NOT transcription complex subunit 8

1

1

High-throughput

0.479

High

64805

TBKB1
TANK-binding kinase 1-binding protein 1

1

0

High-throughput

0.458

High

232235

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.458

High

257625

ANR17
Ankyrin repeat domain-containing protein 17

1

0

High-throughput

0.458

High

326680

SNAI1
Zinc finger protein SNAI1

1

0

High-throughput

0.458

High

386906

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

552931

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

651430

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

815256

TISD
mRNA decay activator protein ZFP36L2

1

0

High-throughput

0.458

High

1033389

ORC1
Origin recognition complex subunit 1

1

0

Small-scale

0.458

High

1038455

HDAC1
Histone deacetylase 1

1

0

High-throughput

0.458

High

1120766

KLH12
Kelch-like protein 12

1

0

Small-scale

0.458

High

1139827

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1139842

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

1139849

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

1139853

PF21A
PHD finger protein 21A

1

0

High-throughput

0.458

High

1139856

RNF31
E3 ubiquitin-protein ligase RNF31

1

0

High-throughput

0.458

High

1139859

IFT74
Intraflagellar transport protein 74 homolog

1

0

High-throughput

0.458

High

1139871

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

Small-scale

0.458

High

1139876

BRF2
Transcription factor IIIB 50 kDa subunit

1

0

High-throughput

0.458

High

1139885

LRWD1
Leucine-rich repeat and WD repeat-containing protein 1

1

0

Small-scale

0.458

High

1139889

RCOR1
REST corepressor 1

1

0

High-throughput

0.458

High

1139834

PELP1
Proline-, glutamic acid- and leucine-rich protein 1

1

0

High-throughput

0.438

High

160622

AURKA
Aurora kinase A

1

1

High-throughput

0.437

High

323421

TTC4
Tetratricopeptide repeat protein 4

1

2

High-throughput

0.437

High

1139826

SYNE3
Nesprin-3

1

1

High-throughput

0.437

High

1139841

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

1

High-throughput

0.437

High

1139848

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

1

High-throughput

0.437

High

1139857

AURKB
Aurora kinase B

1

1

High-throughput

0.437

High

1139893

CP131
Centrosomal protein of 131 kDa

1

1

High-throughput

0.437

High

1139894

TNR6B
Trinucleotide repeat-containing gene 6B protein

1

1

High-throughput

0.437

High

1139895

SMG5
Nonsense-mediated mRNA decay factor SMG5

1

1

High-throughput

0.437

High

1032464

CTBP1
C-terminal-binding protein 1

1

0

High-throughput

0.426

High

1139882

WRP73
WD repeat-containing protein WRAP73

5

0

High-throughput

0.372

High

61385

CNOT1
CCR4-NOT transcription complex subunit 1

4

0

Small-scale

0.364

High

1139875

CNO10
CCR4-NOT transcription complex subunit 10

4

0

Small-scale

0.359

High

1139839

TEANC
Transcription elongation factor A N-terminal and central domain-containing protein

3

0

High-throughput

0.349

High

1139891

CNO11
CCR4-NOT transcription complex subunit 11

3

0

Small-scale

0.344

High

841391

TOB1
Protein Tob1

2

0

High-throughput

0.328

High

1139850

CNOT9
CCR4-NOT transcription complex subunit 9

2

0

Small-scale

0.325

High

716711

CTNA1
Catenin alpha-1

2

0

Small-scale

0.320

High

1139863

CEP89
Centrosomal protein of 89 kDa

2

0

High-throughput

0.305

High

1139851

BAD
Bcl2-associated agonist of cell death

2

0

High-throughput

0.298

High

47936

IFT56
Intraflagellar transport protein 56

1

0

High-throughput

0.279

Low

272356

MTU1
Mitochondrial tRNA-specific 2-thiouridylase 1

1

0

High-throughput

0.279

Low

314340

AHSA1
Activator of 90 kDa heat shock protein ATPase homolog 1

1

0

High-throughput

0.279

Low

323826

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.279

Low

714253

HSP74
Heat shock 70 kDa protein 4

1

0

High-throughput

0.279

Low

886521

RAB15
Ras-related protein Rab-15

1

0

High-throughput

0.279

Low

888495

NANO2
Nanos homolog 2

1

0

High-throughput

0.279

Low

893564

SEM1
26S proteasome complex subunit SEM1

1

0

Small-scale

0.279

Low

1088090

UPP1
Uridine phosphorylase 1

1

0

High-throughput

0.279

Low

1132232

CF141
Uncharacterized protein C6orf141

1

0

High-throughput

0.279

Low

1139824

BORA
Protein aurora borealis

1

0

High-throughput

0.279

Low

1139830

FA83A
Protein FAM83A

1

0

High-throughput

0.279

Low

1139833

AN13A
Ankyrin repeat domain-containing protein 13A

1

0

High-throughput

0.279

Low

1139836

RIBC1
RIB43A-like with coiled-coils protein 1

1

0

High-throughput

0.279

Low

1139837

D2HDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

1139844

UHMK1
Serine/threonine-protein kinase Kist

1

0

High-throughput

0.279

Low

1139858

LOXL4
Lysyl oxidase homolog 4

1

0

High-throughput

0.279

Low

1139861

F218A
Protein FAM218A

1

0

High-throughput

0.279

Low

1139862

FACOS
FANCD2 opposite strand protein

1

0

High-throughput

0.279

Low

1139873

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.279

Low

1139874

SYNCI
Syncoilin

1

0

High-throughput

0.279

Low

1139884

NLK
Serine/threonine-protein kinase NLK

1

0

High-throughput

0.279

Low

1139896

COR2B
Coronin-2B

1

0

High-throughput

0.279

Low

1139828

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.268

Low

1130173

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.261

Low

1139864

PNKP
Bifunctional polynucleotide phosphatase/kinase

1

0

High-throughput

0.251

Low

157339

BCKD
Branched-chain alpha-ketoacid dehydrogenase kinase

1

0

High-throughput

0.249

Low

162854

XPO1
Exportin-1

1

0

High-throughput

0.249

Low

166255

GRRE1
Granule associated Rac and RHOG effector protein 1

1

0

High-throughput

0.249

Low

298581

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.249

Low

422036

LDHB
L-lactate dehydrogenase B chain

1

0

High-throughput

0.249

Low

622483

CCND1
G1/S-specific cyclin-D1

1

0

High-throughput

0.249

Low

639595

TNR5
Tumor necrosis factor receptor superfamily member 5

1

0

High-throughput

0.249

Low

684108

1433S
14-3-3 protein sigma

1

0

High-throughput

0.249

Low

720675

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

742347

SYUA
Alpha-synuclein

1

0

High-throughput

0.249

Low

813536

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.249

Low

841503

KNTC1
Kinetochore-associated protein 1

1

0

High-throughput

0.249

Low

940632

F193A
Protein FAM193A

1

0

High-throughput

0.249

Low

1033421

ORC2
Origin recognition complex subunit 2

1

0

Small-scale

0.249

Low

1034587

GOGA4
Golgin subfamily A member 4

1

0

High-throughput

0.249

Low

1034893

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

0

High-throughput

0.249

Low

1052078

MAP7
Ensconsin

1

0

High-throughput

0.249

Low

1062159

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.249

Low

1066247

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.249

Low

1085770

IF16
Gamma-interferon-inducible protein 16

1

0

High-throughput

0.249

Low

1115721

CRY2
Cryptochrome-2

1

0

High-throughput

0.249

Low

1118961

AMOT
Angiomotin

1

0

High-throughput

0.249

Low

1139825

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.249

Low

1139829

N4BP2
NEDD4-binding protein 2

1

0

High-throughput

0.249

Low

1139835

STK40
Serine/threonine-protein kinase 40

1

0

Small-scale

0.249

Low

1139838

MACOI
Macoilin

1

0

High-throughput

0.249

Low

1139845

DPTOR
DEP domain-containing mTOR-interacting protein

1

0

Small-scale

0.249

Low

1139847

IFT81
Intraflagellar transport protein 81 homolog

1

0

High-throughput

0.249

Low

1139865

MPP9
M-phase phosphoprotein 9

1

0

High-throughput

0.249

Low

1139868

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.249

Low

1139878

Q9HCK3
KIAA1569 protein

1

0

High-throughput

0.249

Low

1139880

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

0

High-throughput

0.249

Low

1139887

TBK1
Serine/threonine-protein kinase TBK1

1

0

High-throughput

0.249

Low

127016

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

0

High-throughput

0.238

Low

301209

RHBT3
Rho-related BTB domain-containing protein 3

1

0

High-throughput

0.238

Low

442231

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.238

Low

809127

UTRN
Utrophin

1

0

High-throughput

0.238

Low

901795

STXB1
Syntaxin-binding protein 1

1

0

High-throughput

0.238

Low

1060212

PTGR1
Prostaglandin reductase 1

1

0

High-throughput

0.238

Low

1139846

UBP33
Ubiquitin carboxyl-terminal hydrolase 33

1

0

High-throughput

0.238

Low

1139852

FUBP1
Far upstream element-binding protein 1

1

0

High-throughput

0.238

Low

230631

KATIP
Katanin-interacting protein

1

0

High-throughput

0.232

Low

275443

PR15A
Protein phosphatase 1 regulatory subunit 15A

1

0

High-throughput

0.232

Low

1139840

MOT11
Monocarboxylate transporter 11

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024