Protein: FAN1
Fanconi-associated nuclease 1 (EC 3.1.21.-) (EC 3.1.4.1) (FANCD2/FANCI-associated nuclease 1) (hFAN1) (Myotubularin-related protein 15)

Gene: FAN1
Organism: Homo sapiens
Interactions: 59
UniProt ID: Q9Y2M0

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0000724 - double-strand break repair via homologous recombination
GO:0004528 - phosphodiesterase I activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1377313

FAN1
Fanconi-associated nuclease 1

3

0

Small-scale

0.809

High

776432

MLH1
DNA mismatch repair protein Mlh1

10

6

Small-scale

0.754

High

869902

PMS2
Mismatch repair endonuclease PMS2

7

6

Small-scale

0.743

High

869858

PMS1
PMS1 protein homolog 1

5

6

Small-scale

0.714

High

1315914

FACD2
Fanconi anemia group D2 protein

6

0

Small-scale

0.693

High

517551

PCNA
Proliferating cell nuclear antigen

2

0

Small-scale

0.598

High

1333202

ZN703
Zinc finger protein 703

2

0

High-throughput

0.585

High

476600

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

0

Small-scale

0.569

High

1346613

FANCI
Fanconi anemia group I protein

2

0

Small-scale

0.559

High

121877

PSD11
26S proteasome non-ATPase regulatory subunit 11

1

0

High-throughput

0.513

High

124129

SPT5H
Transcription elongation factor SPT5

1

0

High-throughput

0.513

High

204524

ARK72
Aflatoxin B1 aldehyde reductase member 2

1

0

High-throughput

0.513

High

302227

AP2A2
AP-2 complex subunit alpha-2

1

0

High-throughput

0.513

High

323509

CAVN2
Caveolae-associated protein 2

1

0

High-throughput

0.513

High

420729

HEXA
Beta-hexosaminidase subunit alpha

1

0

High-throughput

0.513

High

966676

OTUD4
OTU domain-containing protein 4

1

0

High-throughput

0.513

High

1020613

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

0

High-throughput

0.513

High

1037919

PRP4K
Serine/threonine-protein kinase PRP4 homolog

1

0

High-throughput

0.513

High

1218389

WDR75
WD repeat-containing protein 75

1

0

High-throughput

0.513

High

1229955

MIER1
Mesoderm induction early response protein 1

1

0

High-throughput

0.513

High

1236228

CA052
UPF0690 protein C1orf52

1

0

High-throughput

0.513

High

1294965

PKHA8
Pleckstrin homology domain-containing family A member 8

1

0

High-throughput

0.513

High

1335957

NCOA5
Nuclear receptor coactivator 5

1

0

High-throughput

0.513

High

867672

BLM
RecQ-like DNA helicase BLM

1

0

Small-scale

0.493

High

135797

P3C2B
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta

1

1

High-throughput

0.479

High

589257

ANXA7
Annexin A7

1

1

High-throughput

0.479

High

672355

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

1

High-throughput

0.479

High

722063

RFC4
Replication factor C subunit 4

1

1

Small-scale

0.479

High

778056

RFC3
Replication factor C subunit 3

1

1

Small-scale

0.479

High

927686

1433Z
14-3-3 protein zeta/delta

1

1

Small-scale

0.479

High

1157241

H3C
Histone H3.3C

1

1

High-throughput

0.479

High

1355320

MLH3
DNA mismatch repair protein Mlh3

1

6

Small-scale

0.479

High

174448

FANCG
Fanconi anemia group G protein

1

0

Small-scale

0.458

High

201477

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

0

High-throughput

0.458

High

403373

LA
Lupus La protein

1

0

High-throughput

0.458

High

789584

RBM34
RNA-binding protein 34

1

0

High-throughput

0.458

High

867274

TCP4
Activated RNA polymerase II transcriptional coactivator p15

1

0

High-throughput

0.458

High

910190

1433E
14-3-3 protein epsilon

1

0

Small-scale

0.458

High

1060975

IMB1
Importin subunit beta-1

1

0

Small-scale

0.458

High

1193212

SLN11
Schlafen family member 11

1

0

High-throughput

0.458

High

1203684

AROS
Active regulator of SIRT1

1

0

High-throughput

0.458

High

1251209

G45IP
Large ribosomal subunit protein mL64

1

0

High-throughput

0.458

High

1260463

FBLI1
Filamin-binding LIM protein 1

1

0

High-throughput

0.458

High

1281979

RL36L
Ribosomal protein eL42-like

1

0

High-throughput

0.458

High

1288125

NUD16
U8 snoRNA-decapping enzyme

1

0

High-throughput

0.458

High

1357723

TNR6B
Trinucleotide repeat-containing gene 6B protein

1

0

High-throughput

0.458

High

1377314

NOP16
Nucleolar protein 16

1

0

High-throughput

0.458

High

73001

B4DT77
Annexin

1

1

High-throughput

0.445

High

99454

F5GWN5
Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta

1

1

High-throughput

0.445

High

935394

H31
Histone H3.1

1

1

High-throughput

0.445

High

1085376

FSCN1
Fascin

1

0

Small-scale

0.426

High

87321

C9J9C1
Protein phosphatase 2 scaffold subunit Aalpha

1

1

High-throughput

0.407

High

686780

CCR1
C-C chemokine receptor type 1

1

0

High-throughput

0.282

High

1204620

ANKL2
Ankyrin repeat and LEM domain-containing protein 2

1

0

High-throughput

0.279

Low

1254116

C99L2
CD99 antigen-like protein 2

1

0

High-throughput

0.279

Low

1158153

DHX57
Putative ATP-dependent RNA helicase DHX57

1

0

High-throughput

0.249

Low

1349259

HPBP1
Hsp70-binding protein 1

1

0

High-throughput

0.249

Low

886367

DSCR9
Down syndrome critical region protein 9

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024