Protein: MTO1
5-taurinomethyluridine-[tRNA] synthase subunit MTO1, mitochondrial (Mitochondrial tRNA translation optimization 1) (Protein MTO1 homolog, mitochondrial)

Gene: MTO1
Organism: Homo sapiens
Interactions: 84
UniProt ID: Q9Y2Z2

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0030488 - tRNA methylation
GO:0050660 - flavin adenine dinucleotide binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1405921

DNJC7
DnaJ homolog subfamily C member 7

3

0

High-throughput

0.634

High

349717

BPNT1
3'(2'),5'-bisphosphate nucleotidase 1

2

0

High-throughput

0.602

High

946542

YBEY
Endoribonuclease YbeY

2

0

High-throughput

0.602

High

1060940

LRP1
Prolow-density lipoprotein receptor-related protein 1

2

0

High-throughput

0.602

High

1311542

BBS7
BBSome complex member BBS7

2

0

High-throughput

0.602

High

1352208

DQX1
ATP-dependent RNA helicase homolog DQX1

2

0

High-throughput

0.602

High

1394313

TET5A
Terminal nucleotidyltransferase 5A

2

0

High-throughput

0.602

High

1429113

NXF2
Nuclear RNA export factor 2

2

0

High-throughput

0.602

High

1449383

SYIM
Isoleucine--tRNA ligase, mitochondrial

2

0

High-throughput

0.602

High

259182

DNJA2
DnaJ homolog subfamily A member 2

2

1

High-throughput

0.601

High

436759

KPCB
Protein kinase C beta type

2

0

High-throughput

0.547

High

1238418

ACSM5
Acyl-coenzyme A synthetase ACSM5, mitochondrial

1

1

High-throughput

0.536

High

1458453

RBL2A
Rab-like protein 2A

2

1

High-throughput

0.533

High

124540

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.513

High

158521

RFXK
DNA-binding protein RFXANK

1

0

High-throughput

0.513

High

275419

NDUS7
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

1

0

High-throughput

0.513

High

347431

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.513

High

606058

CAN2
Calpain-2 catalytic subunit

1

0

High-throughput

0.513

High

690575

KAD4
Adenylate kinase 4, mitochondrial

1

0

High-throughput

0.513

High

1194124

VP26B
Vacuolar protein sorting-associated protein 26B

1

0

High-throughput

0.513

High

1198422

LRC23
Leucine-rich repeat-containing protein 23

1

0

High-throughput

0.513

High

1218083

CBPC6
Cytosolic carboxypeptidase 6

1

0

High-throughput

0.513

High

1233273

ELP2
Elongator complex protein 2

1

0

High-throughput

0.513

High

1242652

FAHD1
Oxaloacetate tautomerase FAHD1, mitochondrial

1

0

High-throughput

0.513

High

1310044

FXRD2
FAD-dependent oxidoreductase domain-containing protein 2

1

0

High-throughput

0.513

High

1310544

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1389037

MASU1
Mitochondrial assembly of ribosomal large subunit protein 1

1

0

High-throughput

0.513

High

1389245

RT24
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.513

High

1397264

LURA1
Leucine rich adaptor protein 1

1

0

High-throughput

0.513

High

1412776

FEM1A
Protein fem-1 homolog A

1

0

High-throughput

0.513

High

1412924

NAA11
N-alpha-acetyltransferase 11

1

0

High-throughput

0.513

High

1414064

MYL10
Myosin regulatory light chain 10

1

0

High-throughput

0.513

High

1418026

SCOT2
Succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial

1

0

High-throughput

0.513

High

1428334

COMD5
COMM domain-containing protein 5

1

0

High-throughput

0.513

High

1451657

TSAP1
tRNA selenocysteine 1-associated protein 1

1

0

High-throughput

0.513

High

1459134

NPS3A
Protein NipSnap homolog 3A

1

0

High-throughput

0.513

High

1459993

AMACR
Alpha-methylacyl-CoA racemase

1

0

High-throughput

0.513

High

1491010

SYYM
Tyrosine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

1491011

RT02
Small ribosomal subunit protein uS2m

1

0

High-throughput

0.513

High

1429454

DRC3
Dynein regulatory complex subunit 3

1

1

High-throughput

0.489

High

247047

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.486

High

508869

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

856433

IF2M
Translation initiation factor IF-2, mitochondrial

1

1

High-throughput

0.479

High

351046

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

0

High-throughput

0.458

High

471336

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.458

High

1015926

RHOG
Rho-related GTP-binding protein RhoG

1

0

High-throughput

0.458

High

1048761

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1087627

GRSF1
G-rich sequence factor 1

1

0

High-throughput

0.458

High

1106144

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

0

High-throughput

0.458

High

1162628

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.458

High

1178475

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

1207188

SYAM
Alanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.458

High

1452016

THUM1
THUMP domain-containing protein 1

1

0

High-throughput

0.458

High

1419438

RHBT2
Rho-related BTB domain-containing protein 2

1

2

High-throughput

0.437

High

457790

TBB5
Tubulin beta chain

1

0

High-throughput

0.426

High

1135956

FAKD3
FAST kinase domain-containing protein 3, mitochondrial

1

0

Small-scale

0.426

High

1185878

NSN5B
Putative NOL1/NOP2/Sun domain family member 5B

1

0

High-throughput

0.426

High

1452039

TRM1
tRNA

1

0

High-throughput

0.426

High

85426

B7ZBD5
RAB, member of RAS oncogene family like 2A

1

1

High-throughput

0.407

High

888493

TSP3
Thrombospondin-3

3

0

High-throughput

0.347

High

1308255

CCNJL
Cyclin-J-like protein

3

0

High-throughput

0.347

High

1411436

CAB45
45 kDa calcium-binding protein

3

0

High-throughput

0.347

High

389614

RET4
Retinol-binding protein 4

2

0

High-throughput

0.328

High

1128974

I13R2
Interleukin-13 receptor subunit alpha-2

2

0

High-throughput

0.328

High

1233822

CNDH2
Condensin-2 complex subunit H2

2

0

High-throughput

0.328

High

1446817

CRAC1
Cartilage acidic protein 1

2

0

High-throughput

0.328

High

848750

MAGA9
Melanoma-associated antigen 9

1

0

High-throughput

0.279

Low

1101449

SG2A2
Mammaglobin-A

1

0

High-throughput

0.279

Low

1235396

KLH10
Kelch-like protein 10

1

0

High-throughput

0.279

Low

1316650

CDK20
Cyclin-dependent kinase 20

1

0

High-throughput

0.279

Low

1331622

ABTB2
Ankyrin repeat and BTB/POZ domain-containing protein 2

1

0

High-throughput

0.279

Low

1336957

LY65B
Lymphocyte antigen 6 complex locus protein G5b

1

0

High-throughput

0.279

Low

1381171

SNX21
Sorting nexin-21

1

0

High-throughput

0.279

Low

1384953

TRI43
Tripartite motif-containing protein 43

1

0

High-throughput

0.279

Low

1432205

ADAM7
Disintegrin and metalloproteinase domain-containing protein 7

1

0

High-throughput

0.279

Low

1462650

DHDH
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase

1

0

High-throughput

0.279

Low

216569

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

0

High-throughput

0.265

Low

106897

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

342381

BRD1
Bromodomain-containing protein 1

1

0

High-throughput

0.249

Low

635437

C4BPB
C4b-binding protein beta chain

1

0

High-throughput

0.249

Low

696926

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

50044

F170A
Protein FAM170A

1

0

High-throughput

0.232

Low

844981

EAA2
Excitatory amino acid transporter 2

1

0

High-throughput

0.232

Low

1491012

T22D4
TSC22 domain family protein 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025