Protein: EDC4
Enhancer of mRNA-decapping protein 4 (Autoantigen Ge-1) (Autoantigen RCD-8) (Human enhancer of decapping large subunit) (Hedls)

Gene: EDC4
Organism: Homo sapiens
Interactions: 177
UniProt ID: Q6P2E9

Gene Ontology (top 5):
GO:0000932 - P-body
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1159012

DCP1A
mRNA-decapping enzyme 1A

11

7

Small-scale

0.759

High

1158972

DCP2
m7GpppN-mRNA hydrolase

9

2

Small-scale

0.756

High

640511

DDX6
Probable ATP-dependent RNA helicase DDX6

6

8

Small-scale

0.732

High

1158991

SGF29
SAGA-associated factor 29

5

0

High-throughput

0.691

High

802626

CRK
Adapter molecule crk

4

7

High-throughput

0.691

High

1158976

XRN1
5'-3' exoribonuclease 1

4

1

Small-scale

0.691

High

1158992

EDC3
Enhancer of mRNA-decapping protein 3

5

0

Small-scale

0.688

High

726260

BASI
Basigin

3

3

High-throughput

0.667

High

1158975

DCP1B
mRNA-decapping enzyme 1B

3

10

Small-scale

0.665

High

1158979

LS14A
Protein LSM14 homolog A

3

2

Small-scale

0.640

High

742355

SYUA
Alpha-synuclein

3

4

High-throughput

0.633

High

802858

CRKL
Crk-like protein

2

6

High-throughput

0.628

High

817687

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

2

2

High-throughput

0.628

High

1158968

PATL1
Protein PAT1 homolog 1

2

4

Small-scale

0.588

High

585491

E2AK2
Interferon-induced, double-stranded RNA-activated protein kinase

1

4

High-throughput

0.586

High

227795

PRKN
E3 ubiquitin-protein ligase parkin

2

11

High-throughput

0.584

High

552975

RFA2
Replication protein A 32 kDa subunit

2

11

High-throughput

0.584

High

651478

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

6

High-throughput

0.584

High

720722

RFA3
Replication protein A 14 kDa subunit

2

6

High-throughput

0.584

High

1158962

EDC4
Enhancer of mRNA-decapping protein 4

2

7

Small-scale

0.584

High

1159006

WDR76
WD repeat-containing protein 76

2

12

High-throughput

0.584

High

1159015

ANLN
Anillin

2

5

High-throughput

0.584

High

369832

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

3537

NBDY
Negative regulator of P-body association

1

0

Small-scale

0.561

High

843742

FXR1
RNA-binding protein FXR1

1

9

High-throughput

0.541

High

844113

FXR2
RNA-binding protein FXR2

1

9

High-throughput

0.541

High

314072

BAG4
BAG family molecular chaperone regulator 4

1

3

High-throughput

0.536

High

323837

BAG2
BAG family molecular chaperone regulator 2

1

1

High-throughput

0.536

High

358797

CRYAA
Alpha-crystallin A chain

1

1

High-throughput

0.536

High

418370

NPM
Nucleophosmin

1

1

High-throughput

0.536

High

451473

CLCA
Clathrin light chain A

1

1

High-throughput

0.536

High

451694

CLCB
Clathrin light chain B

1

1

High-throughput

0.536

High

502222

BIP
Endoplasmic reticulum chaperone BiP

1

5

High-throughput

0.536

High

506607

BCR
Breakpoint cluster region protein

1

12

High-throughput

0.536

High

609919

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

3

High-throughput

0.536

High

611261

TGM1
Protein-glutamine gamma-glutamyltransferase K

1

1

High-throughput

0.536

High

855670

KIF11
Kinesin-like protein KIF11

1

1

High-throughput

0.536

High

1016555

PNRC1
Proline-rich nuclear receptor coactivator 1

1

1

High-throughput

0.536

High

1121715

RHG15
Rho GTPase-activating protein 15

1

1

High-throughput

0.536

High

1134911

SYT6
Synaptotagmin-6

1

1

High-throughput

0.536

High

1158987

RENT1
Regulator of nonsense transcripts 1

1

2

Small-scale

0.536

High

1158993

AURKB
Aurora kinase B

1

2

High-throughput

0.536

High

1158997

CDC5L
Cell division cycle 5-like protein

1

6

High-throughput

0.536

High

1159003

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

1

5

High-throughput

0.536

High

1159013

PNRC2
Proline-rich nuclear receptor coactivator 2

1

1

High-throughput

0.536

High

1159029

G3BP2
Ras GTPase-activating protein-binding protein 2

1

3

High-throughput

0.536

High

440577

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.513

High

644276

TTP
mRNA decay activator protein ZFP36

1

0

Small-scale

0.513

High

960842

CLH1
Clathrin heavy chain 1

1

0

High-throughput

0.513

High

1158971

ANKL2
Ankyrin repeat and LEM domain-containing protein 2

1

0

High-throughput

0.513

High

1158982

PPR35
Protein phosphatase 1 regulatory subunit 35

1

0

High-throughput

0.513

High

1158994

LURA1
Leucine rich adaptor protein 1

1

0

High-throughput

0.513

High

1158996

VPS35
Vacuolar protein sorting-associated protein 35

1

0

High-throughput

0.513

High

1159018

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.513

High

1159019

GTSE1
G2 and S phase-expressed protein 1

1

0

High-throughput

0.513

High

1159024

PURG
Purine-rich element-binding protein gamma

1

0

High-throughput

0.513

High

894141

CDC42
Cell division control protein 42 homolog

1

12

High-throughput

0.501

High

902634

SUMO2
Small ubiquitin-related modifier 2

1

5

High-throughput

0.501

High

947956

RT11
Small ribosomal subunit protein uS11m

1

2

High-throughput

0.489

High

1158967

UBE3B
Ubiquitin-protein ligase E3B

1

5

High-throughput

0.489

High

1158973

FBX16
F-box only protein 16

1

3

High-throughput

0.489

High

1159027

AT7L1
Ataxin-7-like protein 1

1

9

High-throughput

0.489

High

1159038

WIF1
Wnt inhibitory factor 1

1

2

High-throughput

0.489

High

1159039

NPTN
Neuroplastin

1

2

High-throughput

0.489

High

612869

FBLN1
Fibulin-1

1

2

High-throughput

0.481

High

1050121

GIT2
ARF GTPase-activating protein GIT2

1

6

High-throughput

0.481

High

1158995

YTDC1
YTH domain-containing protein 1

1

1

High-throughput

0.481

High

148950

CTRO
Citron Rho-interacting kinase

1

4

High-throughput

0.479

High

162880

XPO1
Exportin-1

1

1

High-throughput

0.479

High

170398

TIF1A
Transcription intermediary factor 1-alpha

1

15

Small-scale

0.479

High

255868

OBSL1
Obscurin-like protein 1

1

9

High-throughput

0.479

High

266372

TAD2A
Transcriptional adapter 2-alpha

1

4

High-throughput

0.479

High

267772

TAF5L
TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L

1

9

High-throughput

0.479

High

303306

HEXI1
Protein HEXIM1

1

1

High-throughput

0.479

High

391750

H2A1B
Histone H2A type 1-B/E

1

5

High-throughput

0.479

High

402159

JUN
Transcription factor Jun

1

17

High-throughput

0.479

High

529275

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.479

High

575760

VINC
Vinculin

1

3

High-throughput

0.479

High

684127

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

684820

STIP1
Stress-induced-phosphoprotein 1

1

3

High-throughput

0.479

High

707661

H2B1B
Histone H2B type 1-B

1

16

High-throughput

0.479

High

717941

BMI1
Polycomb complex protein BMI-1

1

9

High-throughput

0.479

High

779608

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

808702

YAP1
Transcriptional coactivator YAP1

1

14

High-throughput

0.479

High

835415

GSK3A
Glycogen synthase kinase-3 alpha

1

12

High-throughput

0.479

High

835834

GSK3B
Glycogen synthase kinase-3 beta

1

13

High-throughput

0.479

High

841778

CDK9
Cyclin-dependent kinase 9

1

6

High-throughput

0.479

High

903308

WDR5
WD repeat-containing protein 5

1

7

High-throughput

0.479

High

904722

1433G
14-3-3 protein gamma

1

20

High-throughput

0.479

High

908705

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

5

High-throughput

0.479

High

917453

H4
Histone H4

1

6

High-throughput

0.479

High

961162

HSF1
Heat shock factor protein 1

1

2

High-throughput

0.479

High

962824

MDM2
E3 ubiquitin-protein ligase Mdm2

1

1

Small-scale

0.479

High

966158

NC2B
Protein Dr1

1

2

High-throughput

0.479

High

982150

1433F
14-3-3 protein eta

1

20

High-throughput

0.479

High

1026447

RFA4
Replication protein A 30 kDa subunit

1

11

High-throughput

0.479

High

1030300

G3BP1
Ras GTPase-activating protein-binding protein 1

1

3

High-throughput

0.479

High

1031366

PABP4
Polyadenylate-binding protein 4

1

2

High-throughput

0.479

High

1041824

CUL3
Cullin-3

1

5

High-throughput

0.479

High

1083664

TAF9
Transcription initiation factor TFIID subunit 9

1

1

High-throughput

0.479

High

1085775

IF16
Gamma-interferon-inducible protein 16

1

1

High-throughput

0.479

High

1136128

RC3H1
Roquin-1

1

3

Small-scale

0.479

High

1158965

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.479

High

1158966

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

5

High-throughput

0.479

High

1158969

TAD2B
Transcriptional adapter 2-beta

1

1

High-throughput

0.479

High

1158970

NAA40
N-alpha-acetyltransferase 40

1

5

High-throughput

0.479

High

1158974

ZZZ3
ZZ-type zinc finger-containing protein 3

1

1

High-throughput

0.479

High

1158977

RHG18
Rho GTPase-activating protein 18

1

2

High-throughput

0.479

High

1158978

NHLC2
NHL repeat-containing protein 2

1

1

High-throughput

0.479

High

1158980

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

9

High-throughput

0.479

High

1158985

KAT2A
Histone acetyltransferase KAT2A

1

20

High-throughput

0.479

High

1158986

KAT2B
Histone acetyltransferase KAT2B

1

14

High-throughput

0.479

High

1158988

FGF11
Fibroblast growth factor 11

1

1

High-throughput

0.479

High

1158990

DCPS
m7GpppX diphosphatase

1

2

High-throughput

0.479

High

1158998

ATX2
Ataxin-2

1

6

High-throughput

0.479

High

1159000

CPEB1
Cytoplasmic polyadenylation element-binding protein 1

1

2

High-throughput

0.479

High

1159002

WWTR1
WW domain-containing transcription regulator protein 1

1

10

High-throughput

0.479

High

1159004

PKHA4
Pleckstrin homology domain-containing family A member 4

1

7

High-throughput

0.479

High

1159005

CSR2B
Cysteine-rich protein 2-binding protein

1

5

High-throughput

0.479

High

1159007

AGO3
Protein argonaute-3

1

2

Small-scale

0.479

High

1159008

RC3H2
Roquin-2

1

11

High-throughput

0.479

High

1159010

TAF9B
Transcription initiation factor TFIID subunit 9B

1

1

High-throughput

0.479

High

1159011

MOV10
Helicase MOV-10

1

2

High-throughput

0.479

High

1159014

MED4
Mediator of RNA polymerase II transcription subunit 4

1

1

High-throughput

0.479

High

1159016

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

5

High-throughput

0.479

High

1159017

MBIP1
MAP3K12-binding inhibitory protein 1

1

1

High-throughput

0.479

High

1159023

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

1159025

AGO2
Protein argonaute-2

1

2

High-throughput

0.479

High

1159026

BAG5
BAG family molecular chaperone regulator 5

1

3

High-throughput

0.479

High

1159028

YETS2
YEATS domain-containing protein 2

1

8

High-throughput

0.479

High

1159030

TRI33
E3 ubiquitin-protein ligase TRIM33

1

14

High-throughput

0.479

High

1159031

WDR37
WD repeat-containing protein 37

1

10

High-throughput

0.479

High

1159032

LSM2
U6 snRNA-associated Sm-like protein LSm2

1

1

High-throughput

0.479

High

1159035

TRRAP
Transformation/transcription domain-associated protein

1

2

High-throughput

0.479

High

1159036

MARF1
Meiosis regulator and mRNA stability factor 1

1

1

High-throughput

0.479

High

1159037

LSM4
U6 snRNA-associated Sm-like protein LSm4

1

1

Small-scale

0.479

High

1159040

TAF6L
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L

1

1

High-throughput

0.479

High

528266

CCL5
C-C motif chemokine 5

1

0

High-throughput

0.460

High

266488

SUPT3
Transcription initiation protein SPT3 homolog

1

0

High-throughput

0.458

High

267657

TADA3
Transcriptional adapter 3

1

0

High-throughput

0.458

High

297915

ST65G
STAGA complex 65 subunit gamma

1

0

High-throughput

0.458

High

785968

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.458

High

813550

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.458

High

1035831

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

1109588

LSM12
Protein LSM12

1

0

High-throughput

0.458

High

1148633

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

1158964

MEX3B
RNA-binding protein MEX3B

1

0

High-throughput

0.458

High

1158981

SP20H
Transcription factor SPT20 homolog

1

0

High-throughput

0.458

High

1158989

TADA1
Transcriptional adapter 1

1

0

High-throughput

0.458

High

1159020

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1159021

WWOX
WW domain-containing oxidoreductase

1

0

High-throughput

0.458

High

302648

FA13A
Protein FAM13A

1

4

Small-scale

0.457

High

167700

LSM1
U6 snRNA-associated Sm-like protein LSm1

1

3

Small-scale

0.445

High

1043879

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

15

High-throughput

0.445

High

1057509

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

3

High-throughput

0.445

High

1130219

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

4

High-throughput

0.445

High

1153252

PKHA7
Pleckstrin homology domain-containing family A member 7

1

12

High-throughput

0.445

High

1158984

ESR2
Estrogen receptor beta

1

20

High-throughput

0.445

High

1159001

ZDHC5
Palmitoyltransferase ZDHHC5

1

3

High-throughput

0.445

High

1159022

GRHL1
Grainyhead-like protein 1 homolog

1

3

High-throughput

0.445

High

1159033

CIA2B
Cytosolic iron-sulfur assembly component 2B

1

1

Small-scale

0.445

High

329786

AGR2
Anterior gradient protein 2 homolog

1

4

High-throughput

0.437

High

385014

NTRK1
High affinity nerve growth factor receptor

1

11

High-throughput

0.437

High

230634

KATIP
Katanin-interacting protein

1

0

High-throughput

0.426

High

831430

CEBPA
CCAAT/enhancer-binding protein alpha

1

12

High-throughput

0.408

High

581771

VCAM1
Vascular cell adhesion protein 1

1

4

High-throughput

0.407

High

1158983

CD003
Uncharacterized protein C4orf3

3

0

High-throughput

0.347

High

856401

EFNA4
Ephrin-A4

1

0

High-throughput

0.279

Low

873435

P5CS
Delta-1-pyrroline-5-carboxylate synthase

1

0

High-throughput

0.279

Low

1159034

RT18C
Small ribosomal subunit protein bS18m

1

0

High-throughput

0.279

Low

1023381

COASY
Bifunctional coenzyme A synthase

1

0

Small-scale

0.249

Low

1158963

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

1158999

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

0

High-throughput

0.249

Low

1159009

ZFYV1
Zinc finger FYVE domain-containing protein 1

1

0

Small-scale

0.249

Low

473250

F153B
Protein FAM153B

1

0

High-throughput

0.232

Low

483698

CT456
Cancer/testis antigen family 45 member A6

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024