Protein: LSM2
U6 snRNA-associated Sm-like protein LSm2 (Protein G7b) (Small nuclear ribonuclear protein D homolog) (snRNP core Sm-like protein Sm-x5)

Gene: LSM2
Organism: Homo sapiens
Interactions: 142
UniProt ID: Q9Y333

Gene Ontology (top 5):
GO:0000244 - spliceosomal tri-snRNP complex assembly
GO:0000398 - mRNA splicing, via spliceosome
GO:0000932 - P-body
GO:0003723 - RNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

912205

LSM3
U6 snRNA-associated Sm-like protein LSm3

16

20

Small-scale

0.990

High

1356292

LSM7
U6 snRNA-associated Sm-like protein LSm7

7

20

Small-scale

0.965

High

867492

ICLN
Methylosome subunit pICln

6

10

High-throughput

0.953

High

912257

LSM6
U6 snRNA-associated Sm-like protein LSm6

6

19

High-throughput

0.949

High

911773

RUXE
Small nuclear ribonucleoprotein E

5

11

Small-scale

0.925

High

167726

LSM1
U6 snRNA-associated Sm-like protein LSm1

5

20

High-throughput

0.925

High

539197

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

5

15

High-throughput

0.925

High

912596

SMD2
Small nuclear ribonucleoprotein Sm D2

5

20

Small-scale

0.921

High

912002

RUXF
Small nuclear ribonucleoprotein F

4

19

High-throughput

0.903

High

1063313

SART3
Squamous cell carcinoma antigen recognized by T-cells 3

4

20

High-throughput

0.900

High

1377523

LSM4
U6 snRNA-associated Sm-like protein LSm4

4

16

Small-scale

0.886

High

321440

LSM8
U6 snRNA-associated Sm-like protein LSm8

4

20

Small-scale

0.886

High

202552

PRPF3
U4/U6 small nuclear ribonucleoprotein Prp3

3

7

High-throughput

0.861

High

1198420

PATL1
Protein PAT1 homolog 1

3

6

High-throughput

0.843

High

928046

RSMN
Small nuclear ribonucleoprotein-associated protein N

2

17

High-throughput

0.811

High

1377522

LSM5
U6 snRNA-associated Sm-like protein LSm5

2

20

High-throughput

0.811

High

448861

RU1C
U1 small nuclear ribonucleoprotein C

2

6

High-throughput

0.789

High

1204016

DAA11
Dynein axonemal assembly factor 11

2

11

High-throughput

0.783

High

442613

RU17
U1 small nuclear ribonucleoprotein 70 kDa

2

14

High-throughput

0.754

High

1064875

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

2

11

High-throughput

0.754

High

1159351

PRP8
Pre-mRNA-processing-splicing factor 8

2

7

High-throughput

0.754

High

795931

MAGA6
Melanoma-associated antigen 6

3

2

High-throughput

0.675

High

197110

PRP4
U4/U6 small nuclear ribonucleoprotein Prp4

3

19

High-throughput

0.662

High

1355472

DDX20
Probable ATP-dependent RNA helicase DDX20

2

13

Small-scale

0.624

High

157786

GEMI2
Gem-associated protein 2

1

4

High-throughput

0.618

High

453941

RU2A
U2 small nuclear ribonucleoprotein A'

1

10

High-throughput

0.618

High

912133

RUXG
Small nuclear ribonucleoprotein G

1

20

High-throughput

0.618

High

912402

SMD1
Small nuclear ribonucleoprotein Sm D1

1

14

High-throughput

0.618

High

446847

SNRPA
U1 small nuclear ribonucleoprotein A

2

18

High-throughput

0.611

High

1054694

RBM39
RNA-binding protein 39

2

10

High-throughput

0.611

High

795802

MAGA3
Melanoma-associated antigen 3

2

2

High-throughput

0.606

High

1377015

LZTS1
Leucine zipper putative tumor suppressor 1

2

1

High-throughput

0.606

High

1377521

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

2

4

Small-scale

0.601

High

1270103

PRCC
Proline-rich protein PRCC

2

1

High-throughput

0.600

High

1084943

SMN
Survival motor neuron protein

2

7

Small-scale

0.595

High

1116644

LARP7
La-related protein 7

2

11

High-throughput

0.584

High

1184402

MEPCE
7SK snRNA methylphosphate capping enzyme

2

5

High-throughput

0.584

High

815057

LEG7
Galectin-7

2

0

High-throughput

0.580

High

1109652

LSM12
Protein LSM12

2

0

High-throughput

0.580

High

1335796

CBX8
Chromobox protein homolog 8

2

0

High-throughput

0.580

High

838369

MEOX2
Homeobox protein MOX-2

1

2

High-throughput

0.573

High

981793

REL
Proto-oncogene c-Rel

1

3

High-throughput

0.573

High

1252562

LNX1
E3 ubiquitin-protein ligase LNX

1

2

High-throughput

0.573

High

1317494

TRI54
Tripartite motif-containing protein 54

1

5

High-throughput

0.573

High

681661

DNJA1
DnaJ homolog subfamily A member 1

2

0

Small-scale

0.565

High

1334235

ZN408
Zinc finger protein 408

2

0

Small-scale

0.565

High

993652

TLE5
TLE family member 5

1

0

High-throughput

0.549

High

1238549

BANP
Protein BANP

1

0

High-throughput

0.549

High

1294819

RSRC1
Serine/Arginine-related protein 53

1

1

High-throughput

0.541

High

1242341

PNMA1
Paraneoplastic antigen Ma1

1

0

High-throughput

0.536

High

451613

CLCA
Clathrin light chain A

1

3

High-throughput

0.536

High

451759

CLCB
Clathrin light chain B

1

3

High-throughput

0.536

High

508784

TOP1
DNA topoisomerase 1

1

3

High-throughput

0.536

High

610120

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

5

High-throughput

0.536

High

801474

KI67
Proliferation marker protein Ki-67

1

3

High-throughput

0.536

High

818636

SOX2
Transcription factor SOX-2

1

7

High-throughput

0.536

High

941839

RBM6
RNA-binding protein 6

1

9

High-throughput

0.536

High

996973

SSRP1
FACT complex subunit SSRP1

1

8

High-throughput

0.536

High

1074273

SF3A1
Splicing factor 3A subunit 1

1

6

High-throughput

0.536

High

1084671

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

10

High-throughput

0.536

High

1263590

PSPC1
Paraspeckle component 1

1

3

High-throughput

0.536

High

1312103

RBM42
RNA-binding protein 42

1

12

High-throughput

0.536

High

1344182

DDX21
Nucleolar RNA helicase 2

1

10

High-throughput

0.536

High

690159

GBP2
Guanylate-binding protein 2

1

0

High-throughput

0.518

High

984047

ZBT16
Zinc finger and BTB domain-containing protein 16

1

0

High-throughput

0.518

High

1050911

DPYL1
Dihydropyrimidinase-related protein 1

1

0

High-throughput

0.518

High

1024448

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

4

High-throughput

0.515

High

1034440

SF3B2
Splicing factor 3B subunit 2

1

4

High-throughput

0.508

High

966508

EXOSX
Exosome complex component 10

1

0

High-throughput

0.486

High

531527

K1C13
Keratin, type I cytoskeletal 13

1

1

High-throughput

0.481

High

149452

CTRO
Citron Rho-interacting kinase

1

3

High-throughput

0.479

High

153836

ANM5
Protein arginine N-methyltransferase 5

1

4

High-throughput

0.479

High

203563

PPIH
Peptidyl-prolyl cis-trans isomerase H

1

4

High-throughput

0.479

High

209501

PLRG1
Pleiotropic regulator 1

1

19

High-throughput

0.479

High

230820

AQR
RNA helicase aquarius

1

5

High-throughput

0.479

High

233702

NUPR1
Nuclear protein 1

1

3

High-throughput

0.479

High

236268

PRP17
Pre-mRNA-processing factor 17

1

20

High-throughput

0.479

High

241917

PQBP1
Polyglutamine-binding protein 1

1

1

High-throughput

0.479

High

272315

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

20

High-throughput

0.479

High

295435

RECQ4
ATP-dependent DNA helicase Q4

1

8

High-throughput

0.479

High

300294

PRP6
Pre-mRNA-processing factor 6

1

15

High-throughput

0.479

High

303552

HEXI1
Protein HEXIM1

1

3

High-throughput

0.479

High

313378

CD2B2
CD2 antigen cytoplasmic tail-binding protein 2

1

3

High-throughput

0.479

High

402658

JUN
Transcription factor Jun

1

5

High-throughput

0.479

High

570209

CEBPB
CCAAT/enhancer-binding protein beta

1

6

High-throughput

0.479

High

750552

COIL
Coilin

1

2

High-throughput

0.479

High

813869

CAPZB
F-actin-capping protein subunit beta

1

3

High-throughput

0.479

High

839246

EMD
Emerin

1

1

Small-scale

0.479

High

856136

RBM5
RNA-binding protein 5

1

6

High-throughput

0.479

High

875457

TERA
Transitional endoplasmic reticulum ATPase

1

2

High-throughput

0.479

High

884111

GEMI4
Gem-associated protein 4

1

1

High-throughput

0.479

High

903627

WDR5
WD repeat-containing protein 5

1

20

High-throughput

0.479

High

918177

H4
Histone H4

1

4

High-throughput

0.479

High

949217

LSM11
U7 snRNA-associated Sm-like protein LSm11

1

2

High-throughput

0.479

High

1021782

PP1R8
Nuclear inhibitor of protein phosphatase 1

1

5

High-throughput

0.479

High

1024971

RED
Protein Red

1

1

High-throughput

0.479

High

1039957

SNW1
SNW domain-containing protein 1

1

4

High-throughput

0.479

High

1148390

RHG17
Rho GTPase-activating protein 17

1

3

High-throughput

0.479

High

1159032

EDC4
Enhancer of mRNA-decapping protein 4

1

1

High-throughput

0.479

High

1172373

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.479

High

1201786

ZCH18
Zinc finger CCCH domain-containing protein 18

1

9

High-throughput

0.479

High

1232145

RHG18
Rho GTPase-activating protein 18

1

3

High-throughput

0.479

High

1234277

ZGPAT
Zinc finger CCCH-type with G patch domain-containing protein

1

7

Small-scale

0.479

High

1237678

PDCD7
Programmed cell death protein 7

1

2

High-throughput

0.479

High

1242168

LS14A
Protein LSM14 homolog A

1

6

Small-scale

0.479

High

1263059

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

1

8

High-throughput

0.479

High

1263376

GEMI6
Gem-associated protein 6

1

4

High-throughput

0.479

High

1264452

CTBL1
Beta-catenin-like protein 1

1

1

High-throughput

0.479

High

1267790

HS105
Heat shock protein 105 kDa

1

3

High-throughput

0.479

High

1269991

ESR2
Estrogen receptor beta

1

6

High-throughput

0.479

High

1286500

DCPS
m7GpppX diphosphatase

1

3

High-throughput

0.479

High

1288404

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

14

High-throughput

0.479

High

1291010

EDC3
Enhancer of mRNA-decapping protein 3

1

2

High-throughput

0.479

High

1303881

CDC5L
Cell division cycle 5-like protein

1

8

High-throughput

0.479

High

1310560

RIOK1
Serine/threonine-protein kinase RIO1

1

3

High-throughput

0.479

High

1313225

DDX23
Probable ATP-dependent RNA helicase DDX23

1

12

High-throughput

0.479

High

1318167

CRNL1
Crooked neck-like protein 1

1

20

High-throughput

0.479

High

1334988

BRF2
Transcription factor IIIB 50 kDa subunit

1

3

Small-scale

0.479

High

1336315

CHD8
Chromodomain-helicase-DNA-binding protein 8

1

4

Small-scale

0.479

High

1344024

BIRC6
Baculoviral IAP repeat-containing protein 6

1

3

High-throughput

0.479

High

1347100

RBM22
Pre-mRNA-splicing factor RBM22

1

8

High-throughput

0.479

High

1347579

GEMI8
Gem-associated protein 8

1

3

High-throughput

0.479

High

1354947

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

1357212

FZR1
Fizzy-related protein homolog

1

14

High-throughput

0.479

High

1377445

WBP11
WW domain-binding protein 11

1

1

High-throughput

0.479

High

1377520

PPIL1
Peptidyl-prolyl cis-trans isomerase-like 1

1

6

High-throughput

0.479

High

1377524

TSSC4
U5 small nuclear ribonucleoprotein TSSC4

1

3

High-throughput

0.479

High

49587

A1A4E9
Keratin 13

1

1

High-throughput

0.470

High

1068990

PCM1
Pericentriolar material 1 protein

1

0

High-throughput

0.460

High

607744

NDKB
Nucleoside diphosphate kinase B

1

0

High-throughput

0.458

High

856047

ZN143
Zinc finger protein 143

1

0

Small-scale

0.458

High

1245353

KNL1
Kinetochore scaffold 1

1

0

High-throughput

0.458

High

3544

NBDY
Negative regulator of P-body association

1

1

Small-scale

0.445

High

306362

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

12

High-throughput

0.445

High

1047341

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

2

High-throughput

0.445

High

1328070

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

12

High-throughput

0.445

High

506431

RALA
Ras-related protein Ral-A

1

1

Small-scale

0.439

High

321257

PTBP3
Polypyrimidine tract-binding protein 3

1

0

High-throughput

0.426

High

831831

CEBPA
CCAAT/enhancer-binding protein alpha

1

6

High-throughput

0.408

High

1223145

TEX11
Testis-expressed protein 11

1

0

High-throughput

0.292

High

1356554

ERG28
Ergosterol biosynthetic protein 28 homolog

1

0

High-throughput

0.282

High

391269

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024