Protein: HKDC1
Hexokinase HKDC1 (EC 2.7.1.1) (Hexokinase domain-containing protein 1)

Gene: HKDC1
Organism: Homo sapiens
Interactions: 48
UniProt ID: Q2TB90

Gene Ontology (top 5):
GO:0001678 - intracellular glucose homeostasis
GO:0001917 - photoreceptor inner segment
GO:0004340 - glucokinase activity
GO:0005524 - ATP binding
GO:0005536 - D-glucose binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

621481

HXK1
Hexokinase-1

5

14

High-throughput

0.919

High

914151

HXK3
Hexokinase-3

2

14

High-throughput

0.811

High

655997

CAH6
Carbonic anhydrase 6

1

1

High-throughput

0.536

High

702397

CYTD
Cystatin-D

1

1

High-throughput

0.536

High

724686

MK04
Mitogen-activated protein kinase 4

1

2

High-throughput

0.536

High

727826

DNJA1
DnaJ homolog subfamily A member 1

1

3

High-throughput

0.536

High

774392

BASI
Basigin

1

1

High-throughput

0.536

High

1023790

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

1

High-throughput

0.536

High

1180370

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.536

High

1180381

CST11
Cystatin-11

1

1

High-throughput

0.536

High

1180385

LSM7
U6 snRNA-associated Sm-like protein LSm7

1

1

High-throughput

0.536

High

1138839

SYLM
Leucine--tRNA ligase, mitochondrial

1

1

High-throughput

0.515

High

485972

CD3G
T-cell surface glycoprotein CD3 gamma chain

1

0

High-throughput

0.513

High

1180376

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

1

0

High-throughput

0.513

High

1180379

SCOT2
Succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial

1

0

High-throughput

0.513

High

1180373

H2B1H
Histone H2B type 1-H

1

0

High-throughput

0.493

High

1180383

CAH10
Carbonic anhydrase-related protein 10

1

1

High-throughput

0.489

High

1180386

DHDH
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase

1

1

High-throughput

0.489

High

363359

EGFR
Epidermal growth factor receptor

1

2

Small-scale

0.479

High

693770

RL10
Large ribosomal subunit protein uL16

1

1

High-throughput

0.479

High

861187

MAP1B
Microtubule-associated protein 1B

1

2

High-throughput

0.479

High

1113240

CUL3
Cullin-3

1

4

High-throughput

0.479

High

1114861

CUL4A
Cullin-4A

1

4

High-throughput

0.479

High

1180377

RL10L
Ribosomal protein uL16-like

1

1

High-throughput

0.479

High

1180384

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

482492

F16P1
Fructose-1,6-bisphosphatase 1

1

0

High-throughput

0.458

High

766209

NOS2
Nitric oxide synthase, inducible

1

0

High-throughput

0.458

High

840722

RS27
Small ribosomal subunit protein eS27

1

0

High-throughput

0.458

High

1035667

KIF23
Kinesin-like protein KIF23

1

0

High-throughput

0.458

High

1141637

EEA1
Early endosome antigen 1

1

0

High-throughput

0.458

High

1180380

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

0

High-throughput

0.458

High

1180387

ITM2B
Integral membrane protein 2B

1

2

High-throughput

0.445

High

260871

RAMP3
Receptor activity-modifying protein 3

1

0

High-throughput

0.279

Low

298851

LYZL6
Lysozyme-like protein 6

1

0

High-throughput

0.279

Low

760446

SDC2
Syndecan-2

1

0

High-throughput

0.279

Low

1029601

CD83
CD83 antigen

1

0

High-throughput

0.279

Low

1090092

KLRB1
Killer cell lectin-like receptor subfamily B member 1

1

0

High-throughput

0.279

Low

1180366

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

1

0

High-throughput

0.279

Low

1180367

SPRY7
SPRY domain-containing protein 7

1

0

High-throughput

0.279

Low

1180368

VSTM1
V-set and transmembrane domain-containing protein 1

1

0

High-throughput

0.279

Low

1180369

TMM25
Transmembrane protein 25

1

0

High-throughput

0.279

Low

1180371

WFD11
Protein WFDC11

1

0

High-throughput

0.279

Low

1180372

MCFD2
Multiple coagulation factor deficiency protein 2

1

0

High-throughput

0.279

Low

1180374

UCN3
Urocortin-3

1

0

High-throughput

0.279

Low

1180375

SNX21
Sorting nexin-21

1

0

High-throughput

0.279

Low

1180378

GML
Glycosyl-phosphatidylinositol-anchored molecule-like protein

1

0

High-throughput

0.279

Low

1180382

ADAM7
Disintegrin and metalloproteinase domain-containing protein 7

1

0

High-throughput

0.279

Low

1180388

SALL2
Sal-like protein 2

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025