Protein: MED20
Mediator of RNA polymerase II transcription subunit 20 (Mediator complex subunit 20) (TRF-proximal protein homolog) (hTRFP)

Gene: MED20
Organism: Homo sapiens
Interactions: 182
UniProt ID: Q9H944

Gene Ontology (top 5):
GO:0003713 - transcription coactivator activity
GO:0003899 - DNA-directed 5'-3' RNA polymerase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006351 - DNA-templated transcription

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1312761

MED18
Mediator of RNA polymerase II transcription subunit 18

12

2

Small-scale

0.985

High

1158924

MED27
Mediator of RNA polymerase II transcription subunit 27

5

1

Small-scale

0.930

High

1334002

MED17
Mediator of RNA polymerase II transcription subunit 17

4

1

High-throughput

0.906

High

826358

CDK8
Cyclin-dependent kinase 8

11

3

Small-scale

0.758

High

1312296

MED10
Mediator of RNA polymerase II transcription subunit 10

9

1

Small-scale

0.755

High

1334005

MED29
Mediator of RNA polymerase II transcription subunit 29

8

1

Small-scale

0.754

High

1076201

MED1
Mediator of RNA polymerase II transcription subunit 1

7

1

Small-scale

0.748

High

1274347

MED12
Mediator of RNA polymerase II transcription subunit 12

7

1

High-throughput

0.748

High

1328951

MED28
Mediator of RNA polymerase II transcription subunit 28

7

1

Small-scale

0.747

High

1293703

MED30
Mediator of RNA polymerase II transcription subunit 30

6

2

Small-scale

0.737

High

1314881

CDK19
Cyclin-dependent kinase 19

6

3

High-throughput

0.733

High

48728

MED19
Mediator of RNA polymerase II transcription subunit 19

9

0

Small-scale

0.724

High

206652

MED7
Mediator of RNA polymerase II transcription subunit 7

5

1

High-throughput

0.722

High

624511

CCNC
Cyclin-C

5

1

High-throughput

0.714

High

1291846

MED8
Mediator of RNA polymerase II transcription subunit 8

4

1

High-throughput

0.702

High

1334001

MED4
Mediator of RNA polymerase II transcription subunit 4

4

1

High-throughput

0.702

High

1334003

MED9
Mediator of RNA polymerase II transcription subunit 9

6

0

Small-scale

0.701

High

225421

MED14
Mediator of RNA polymerase II transcription subunit 14

4

3

High-throughput

0.699

High

270531

MED6
Mediator of RNA polymerase II transcription subunit 6

4

2

High-throughput

0.699

High

1074728

MED22
Mediator of RNA polymerase II transcription subunit 22

4

1

High-throughput

0.699

High

1334006

MED11
Mediator of RNA polymerase II transcription subunit 11

4

1

High-throughput

0.699

High

1334016

MED16
Mediator of RNA polymerase II transcription subunit 16

4

1

High-throughput

0.699

High

1037100

MED21
Mediator of RNA polymerase II transcription subunit 21

5

0

High-throughput

0.694

High

1334018

MED31
Mediator of RNA polymerase II transcription subunit 31

3

1

High-throughput

0.675

High

265364

MED24
Mediator of RNA polymerase II transcription subunit 24

4

0

High-throughput

0.670

High

313466

MED26
Mediator of RNA polymerase II transcription subunit 26

4

0

High-throughput

0.670

High

1301092

MED15
Mediator of RNA polymerase II transcription subunit 15

3

1

High-throughput

0.667

High

1334010

MED13
Mediator of RNA polymerase II transcription subunit 13

3

1

High-throughput

0.662

High

370463

ESR1
Estrogen receptor

3

3

Small-scale

0.660

High

1174778

MD13L
Mediator of RNA polymerase II transcription subunit 13-like

3

1

High-throughput

0.650

High

1334014

MED23
Mediator of RNA polymerase II transcription subunit 23

3

0

High-throughput

0.649

High

475194

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

2

1

High-throughput

0.628

High

625046

RPB1
DNA-directed RNA polymerase II subunit RPB1

3

0

High-throughput

0.628

High

1206160

MD12L
Mediator of RNA polymerase II transcription subunit 12-like protein

2

1

High-throughput

0.611

High

177722

BIRC5
Baculoviral IAP repeat-containing protein 5

2

0

High-throughput

0.602

High

638402

RBTN2
Rhombotin-2

2

0

High-throughput

0.602

High

1269642

ESR2
Estrogen receptor beta

2

3

Small-scale

0.595

High

583584

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.586

High

632912

TYY1
Transcriptional repressor protein YY1

2

0

High-throughput

0.580

High

987843

GABP1
GA-binding protein subunit beta-1

2

0

High-throughput

0.580

High

1149956

NB5R2
NADH-cytochrome b5 reductase 2

2

0

High-throughput

0.580

High

1203452

TRI69
E3 ubiquitin-protein ligase TRIM69

2

0

High-throughput

0.580

High

570072

CEBPB
CCAAT/enhancer-binding protein beta

1

3

Small-scale

0.561

High

244953

BRD4
Bromodomain-containing protein 4

2

0

High-throughput

0.559

High

1334000

RPA2
DNA-directed RNA polymerase I subunit RPA2

1

1

High-throughput

0.541

High

128305

IF2B3
Insulin-like growth factor 2 mRNA-binding protein 3

1

1

High-throughput

0.536

High

606973

SCP2
Sterol carrier protein 2

1

1

High-throughput

0.536

High

613018

TCEA1
Transcription elongation factor A protein 1

1

1

High-throughput

0.536

High

719153

PHB1
Prohibitin 1

1

1

High-throughput

0.536

High

801955

RECQ1
ATP-dependent DNA helicase Q1

1

1

High-throughput

0.536

High

872217

RD23A
UV excision repair protein RAD23 homolog A

1

3

High-throughput

0.536

High

872308

RD23B
UV excision repair protein RAD23 homolog B

1

2

High-throughput

0.536

High

1052773

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

1

High-throughput

0.536

High

1235805

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

1

High-throughput

0.536

High

1246370

THOC2
THO complex subunit 2

1

1

High-throughput

0.536

High

1305266

PHB2
Prohibitin-2

1

1

High-throughput

0.536

High

1310508

RIOK1
Serine/threonine-protein kinase RIO1

1

1

High-throughput

0.536

High

1334004

SLTM
SAFB-like transcription modulator

1

1

High-throughput

0.536

High

181457

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

0

High-throughput

0.513

High

259789

PDCD6
Programmed cell death protein 6

1

0

High-throughput

0.513

High

276215

PSD10
26S proteasome non-ATPase regulatory subunit 10

1

0

High-throughput

0.513

High

363917

ALBU
Albumin

1

0

High-throughput

0.513

High

544759

ALDR
Aldo-keto reductase family 1 member B1

1

0

High-throughput

0.513

High

583801

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

0

High-throughput

0.513

High

586989

CSK22
Casein kinase II subunit alpha'

1

0

High-throughput

0.513

High

601369

VDAC1
Voltage-dependent anion-selective channel protein 1

1

0

High-throughput

0.513

High

623380

AT5F1
ATP synthase F(0) complex subunit B1, mitochondrial

1

0

High-throughput

0.513

High

636421

DNJB1
DnaJ homolog subfamily B member 1

1

0

High-throughput

0.513

High

666970

TKT
Transketolase

1

0

High-throughput

0.513

High

722648

T2FA
General transcription factor IIF subunit 1

1

0

High-throughput

0.513

High

788229

CASP3
Caspase-3

1

0

High-throughput

0.513

High

803753

BAG6
Large proline-rich protein BAG6

1

0

High-throughput

0.513

High

876276

MANF
Mesencephalic astrocyte-derived neurotrophic factor

1

0

High-throughput

0.513

High

878569

PSA
Puromycin-sensitive aminopeptidase

1

0

High-throughput

0.513

High

880056

RRP1
Ribosomal RNA processing protein 1 homolog A

1

0

High-throughput

0.513

High

888218

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.513

High

900918

RHOA
Transforming protein RhoA

1

0

High-throughput

0.513

High

912113

RUXG
Small nuclear ribonucleoprotein G

1

0

High-throughput

0.513

High

925129

TRA2B
Transformer-2 protein homolog beta

1

0

High-throughput

0.513

High

958524

CYC
Cytochrome c

1

0

High-throughput

0.513

High

998188

NCBP1
Nuclear cap-binding protein subunit 1

1

0

High-throughput

0.513

High

1023240

FLII
Protein flightless-1 homolog

1

0

High-throughput

0.513

High

1028825

SRSF5
Serine/arginine-rich splicing factor 5

1

0

High-throughput

0.513

High

1053295

FA50A
Protein FAM50A

1

0

High-throughput

0.513

High

1150724

SUMO4
Small ubiquitin-related modifier 4

1

0

High-throughput

0.513

High

1160895

FXL19
F-box/LRR-repeat protein 19

1

0

High-throughput

0.513

High

1174966

MED25
Mediator of RNA polymerase II transcription subunit 25

1

0

High-throughput

0.513

High

1192218

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.513

High

1284971

EXOS8
Exosome complex component RRP43

1

0

High-throughput

0.513

High

1308608

CND3
Condensin complex subunit 3

1

0

High-throughput

0.513

High

1334017

SGT1
Protein SGT1 homolog

1

0

High-throughput

0.513

High

476395

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

1

High-throughput

0.501

High

1170087

SRCAP
Helicase SRCAP

1

0

High-throughput

0.493

High

574752

ARF4
ADP-ribosylation factor 4

1

1

High-throughput

0.489

High

950715

ARF5
ADP-ribosylation factor 5

1

1

High-throughput

0.489

High

1184575

RSRC2
Arginine/serine-rich coiled-coil protein 2

1

1

High-throughput

0.489

High

1268505

ANS1A
Ankyrin repeat and SAM domain-containing protein 1A

1

1

High-throughput

0.481

High

554517

GATA1
Erythroid transcription factor

1

0

Small-scale

0.479

High

266428

TAD2A
Transcriptional adapter 2-alpha

1

2

High-throughput

0.479

High

295562

RECQ5
ATP-dependent DNA helicase Q5

1

1

High-throughput

0.479

High

377692

GCR
Glucocorticoid receptor

1

3

Small-scale

0.479

High

487768

ANDR
Androgen receptor

1

3

High-throughput

0.479

High

677008

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

1

High-throughput

0.479

High

738887

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

1

High-throughput

0.479

High

831698

CEBPA
CCAAT/enhancer-binding protein alpha

1

3

High-throughput

0.479

High

831932

CEBPD
CCAAT/enhancer-binding protein delta

1

3

Small-scale

0.479

High

1072024

PCBP1
Poly(rC)-binding protein 1

1

1

High-throughput

0.479

High

1078666

SMAD2
Mothers against decapentaplegic homolog 2

1

1

Small-scale

0.479

High

1078759

SMAD1
Mothers against decapentaplegic homolog 1

1

1

Small-scale

0.479

High

1132739

ZC3HD
Zinc finger CCCH domain-containing protein 13

1

1

High-throughput

0.479

High

1115818

Q49AR9
ANKS1A protein

1

1

High-throughput

0.470

High

1153097

Q6IPE9
MARK4 protein

1

1

High-throughput

0.470

High

304658

SCAF4
SR-related and CTD-associated factor 4

1

0

High-throughput

0.458

High

374890

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

568280

ATF7
Cyclic AMP-dependent transcription factor ATF-7

1

0

Small-scale

0.458

High

807537

RS10
Small ribosomal subunit protein eS10

1

0

High-throughput

0.458

High

854369

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

0

High-throughput

0.458

High

854472

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

1

0

High-throughput

0.458

High

864989

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

0

High-throughput

0.458

High

897630

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.458

High

913956

RPB7
DNA-directed RNA polymerase II subunit RPB7

1

0

High-throughput

0.458

High

921167

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

1

0

High-throughput

0.458

High

961276

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.458

High

1019130

TP53B
TP53-binding protein 1

1

0

High-throughput

0.458

High

1046758

KLF5
Krueppel-like factor 5

1

0

Small-scale

0.458

High

1137953

RPRD2
Regulation of nuclear pre-mRNA domain-containing protein 2

1

0

High-throughput

0.458

High

1173765

ACD11
Acyl-CoA dehydrogenase family member 11

1

0

High-throughput

0.458

High

1174228

MOB2
MOB kinase activator 2

1

0

High-throughput

0.458

High

1221366

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

1

0

High-throughput

0.458

High

1281396

FBXW7
F-box/WD repeat-containing protein 7

1

0

Small-scale

0.458

High

1306538

EPAS1
Endothelial PAS domain-containing protein 1

1

0

Small-scale

0.458

High

1334009

PRGC1
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha

1

0

Small-scale

0.458

High

73042

B4DUB1
cDNA FLJ50029, highly similar to Cell division cycle 2-like protein kinase 6

1

3

High-throughput

0.445

High

91311

E5RFK5
Cyclin-C

1

1

High-throughput

0.445

High

1117799

Q4LE69
1-phosphatidylinositol 4-kinase

1

1

High-throughput

0.437

High

1146847

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.437

High

1301386

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.426

High

787689

PI4KA
Phosphatidylinositol 4-kinase alpha

1

1

High-throughput

0.407

High

329045

TCL1B
T-cell leukemia/lymphoma protein 1B

3

0

High-throughput

0.347

High

1262331

PIHD2
PIH1 domain-containing protein 2

2

0

High-throughput

0.316

High

1288441

ERP27
Endoplasmic reticulum resident protein 27

2

0

High-throughput

0.316

High

1334012

PS1C2
Psoriasis susceptibility 1 candidate gene 2 protein

2

0

High-throughput

0.316

High

996227

CLM6
CMRF35-like molecule 6

1

0

High-throughput

0.282

High

202780

TPD54
Tumor protein D54

1

0

High-throughput

0.279

Low

233961

GDF9
Growth/differentiation factor 9

1

0

High-throughput

0.279

Low

336789

CERU
Ceruloplasmin

1

0

High-throughput

0.279

Low

344714

CO3
Complement C3

1

0

High-throughput

0.279

Low

451967

CN37
2',3'-cyclic-nucleotide 3'-phosphodiesterase

1

0

High-throughput

0.279

Low

736057

ATPG
ATP synthase subunit gamma, mitochondrial

1

0

High-throughput

0.279

Low

736127

VATE1
V-type proton ATPase subunit E 1

1

0

High-throughput

0.279

Low

777473

MDHC
Malate dehydrogenase, cytoplasmic

1

0

High-throughput

0.279

Low

808034

GNPI1
Glucosamine-6-phosphate isomerase 1

1

0

High-throughput

0.279

Low

839681

SERPH
Serpin H1

1

0

High-throughput

0.279

Low

895553

RAB10
Ras-related protein Rab-10

1

0

High-throughput

0.279

Low

923839

FKB1A
Peptidyl-prolyl cis-trans isomerase FKBP1A

1

0

High-throughput

0.279

Low

943961

GSTO1
Glutathione S-transferase omega-1

1

0

High-throughput

0.279

Low

1022599

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

0

High-throughput

0.279

Low

1045522

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

0

High-throughput

0.279

Low

1071842

TMED2
Transmembrane emp24 domain-containing protein 2

1

0

High-throughput

0.279

Low

1086960

QPCT
Glutaminyl-peptide cyclotransferase

1

0

High-throughput

0.279

Low

1189806

MYH14
Myosin-14

1

0

High-throughput

0.279

Low

1216763

TPPC5
Trafficking protein particle complex subunit 5

1

0

High-throughput

0.279

Low

1229724

SPART
Spartin

1

0

High-throughput

0.279

Low

1230968

LRC47
Leucine-rich repeat-containing protein 47

1

0

High-throughput

0.279

Low

1262664

CKAP2
Cytoskeleton-associated protein 2

1

0

High-throughput

0.279

Low

1299720

CMA1A
Ciliary microtubule associated protein 1A

1

0

High-throughput

0.279

Low

1314568

THIC
Acetyl-CoA acetyltransferase, cytosolic

1

0

High-throughput

0.279

Low

1318487

UCK2
Uridine-cytidine kinase 2

1

0

High-throughput

0.279

Low

1334008

GBG12

1

0

High-throughput

0.279

Low

1334011

VATH
V-type proton ATPase subunit H

1

0

High-throughput

0.279

Low

1334013

ATIF1
ATPase inhibitor, mitochondrial

1

0

High-throughput

0.279

Low

1334015

COR1C
Coronin-1C

1

0

High-throughput

0.279

Low

1334019

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

0

High-throughput

0.279

Low

1296787

MARK4
MAP/microtubule affinity-regulating kinase 4

1

0

High-throughput

0.251

Low

361610

APOA2
Apolipoprotein A-II

1

0

High-throughput

0.249

Low

1067826

PDIA6
Protein disulfide-isomerase A6

1

0

High-throughput

0.249

Low

1069333

IPYR
Inorganic pyrophosphatase

1

0

High-throughput

0.249

Low

1150696

GL1AD
DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5

1

0

High-throughput

0.249

Low

1267031

WASF1
Actin-binding protein WASF1

1

0

High-throughput

0.249

Low

1334007

KCMF1
E3 ubiquitin-protein ligase KCMF1

1

0

High-throughput

0.249

Low

473923

GRL1A
DNA-directed RNA polymerase II subunit GRINL1A

1

0

High-throughput

0.232

Low

484555

GAL3A
Glutamine amidotransferase-like class 1 domain-containing protein 3, mitochondrial

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024