Protein: PEPD
Xaa-Pro dipeptidase (X-Pro dipeptidase) (EC 3.4.13.9) (Imidodipeptidase) (Peptidase D) (Proline dipeptidase) (Prolidase)

Gene: PEPD
Organism: Homo sapiens
Interactions: 24
UniProt ID: P12955

Gene Ontology (top 5):
GO:0004181 - metallocarboxypeptidase activity
GO:0006508 - proteolysis
GO:0006520 - amino acid metabolic process
GO:0008233 - peptidase activity
GO:0030145 - manganese ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

557798

ATX1
Ataxin-1

2

1

High-throughput

0.566

High

105223

APRIO
Alternative prion protein

2

1

High-throughput

0.533

High

522234

OSTP
Osteopontin

1

0

High-throughput

0.518

High

557802

CUL2
Cullin-2

1

4

High-throughput

0.489

High

557811

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

0

Small-scale

0.486

High

557801

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

1

High-throughput

0.479

High

557803

CUL3
Cullin-3

1

4

High-throughput

0.479

High

557809

SERB1
SERPINE1 mRNA-binding protein 1

1

1

High-throughput

0.479

High

345313

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

240617

PRKN
E3 ubiquitin-protein ligase parkin

1

5

High-throughput

0.437

High

557800

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.437

High

557804

TRI14
Tripartite motif-containing protein 14

1

1

High-throughput

0.437

High

557806

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.437

High

557807

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.437

High

528968

TAU
Microtubule-associated protein tau

1

1

High-throughput

0.407

High

557799

TERF1
Telomeric repeat-binding factor 1

1

0

High-throughput

0.299

High

128496

RN103
E3 ubiquitin-protein ligase RNF103

1

0

High-throughput

0.249

Low

557797

SYUA
Alpha-synuclein

1

0

High-throughput

0.249

Low

557808

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.249

Low

557810

TOPB1
DNA topoisomerase 2-binding protein 1

1

0

High-throughput

0.249

Low

557812

RNF5
E3 ubiquitin-protein ligase RNF5

1

0

High-throughput

0.249

Low

557813

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

557814

TRI17
E3 ubiquitin-protein ligase TRIM17

1

0

Small-scale

0.249

Low

557805

KLH22
Kelch-like protein 22

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025