Protein: EGLN
Endoglin (Cell surface MJ7/18 antigen) (CD antigen CD105)

Gene: EGLN, Eng
Organism: Mus musculus
Interactions: 38
UniProt ID: Q63961

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0001569 - branching involved in blood vessel morphogenesis
GO:0001570 - vasculogenesis
GO:0001947 - heart looping
GO:0003148 - outflow tract septum morphogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1222620

ACVL1
Activin receptor type-1-like

2

12

Small-scale

0.584

High

1224656

TGFR1
TGF-beta receptor type-1

2

12

Small-scale

0.584

High

478526

ITB1
Integrin beta-1

1

1

Small-scale

0.479

High

548163

ITA5
Integrin alpha-5

1

1

Small-scale

0.479

High

1223988

TGFR2
TGF-beta receptor type-2

1

12

Small-scale

0.479

High

1224663

Q91XL1
Leucine-rich HEV glycoprotein

1

3

Small-scale

0.479

High

1224672

WWTR1
WW domain-containing transcription regulator protein 1

1

1

High-throughput

0.479

High

1000072

NOS3
Nitric oxide synthase 3

1

0

High-throughput

0.458

High

1000416

IRF7
Interferon regulatory factor 7

1

0

High-throughput

0.458

High

1221600

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

0

High-throughput

0.458

High

1224665

UBP16
Ubiquitin carboxyl-terminal hydrolase 16

1

0

High-throughput

0.458

High

1224669

TSSK4
Testis-specific serine/threonine-protein kinase 4

1

0

High-throughput

0.458

High

1224676

PKHB1
Pleckstrin homology domain-containing family B member 1

1

0

High-throughput

0.458

High

398489

CFAD
Complement factor D

1

2

High-throughput

0.437

High

1222292

FZD7
Frizzled-7

1

1

High-throughput

0.437

High

1224662

WDR13
WD repeat-containing protein 13

1

3

High-throughput

0.437

High

1224664

UBXN1
UBX domain-containing protein 1

1

1

High-throughput

0.437

High

1224666

ARL4D
ADP-ribosylation factor-like protein 4D

1

1

High-throughput

0.437

High

1224668

TRI13
E3 ubiquitin-protein ligase TRIM13

1

1

High-throughput

0.437

High

1224670

ARL5B
ADP-ribosylation factor-like protein 5B

1

1

High-throughput

0.437

High

1224675

SKI8
Superkiller complex protein 8

1

2

High-throughput

0.437

High

1224679

TBL2
Transducin beta-like protein 2

1

2

High-throughput

0.437

High

1224680

SEC12
Guanine nucleotide-exchange factor SEC12

1

2

High-throughput

0.437

High

109231

G5E884
non-specific serine/threonine protein kinase

1

0

High-throughput

0.249

Low

931632

RD23A
UV excision repair protein RAD23 homolog A

1

0

High-throughput

0.249

Low

994007

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

0

High-throughput

0.249

Low

1223346

RANT
GTP-binding nuclear protein Ran, testis-specific isoform

1

0

High-throughput

0.249

Low

1224657

BCR
Breakpoint cluster region protein

1

0

High-throughput

0.249

Low

1224658

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

0

High-throughput

0.249

Low

1224659

SPOP
Speckle-type POZ protein

1

0

High-throughput

0.249

Low

1224660

FNDC5
Fibronectin type III domain-containing protein 5

1

0

High-throughput

0.249

Low

1224661

ES8L1
Epidermal growth factor receptor kinase substrate 8-like protein 1

1

0

High-throughput

0.249

Low

1224667

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

0

High-throughput

0.249

Low

1224671

FBX3
F-box only protein 3

1

0

High-throughput

0.249

Low

1224673

FXL12
F-box/LRR-repeat protein 12

1

0

High-throughput

0.249

Low

1224674

RGPS2
Ras-specific guanine nucleotide-releasing factor RalGPS2

1

0

High-throughput

0.249

Low

1224677

DNJC7
DnaJ homolog subfamily C member 7

1

0

High-throughput

0.249

Low

1224678

E2AK4
eIF-2-alpha kinase GCN2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025