HitPredict - High confidence protein-protein interactions

Protein: GFRA2
GDNF family receptor alpha-2 (GDNF receptor alpha-2) (GDNFR-alpha-2) (GFR-alpha-2) (GDNF receptor beta) (GDNFR-beta) (Neurturin receptor alpha) (NRTNR-alpha) (NTNR-alpha) (RET ligand 2) (TGF-beta-related neurotrophic factor receptor 2)

Gene: GFRA2
Organism: Homo sapiens
Interactions: 6
UniProt ID: O00451

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0007169 - cell surface receptor protein tyrosine kinase signaling pathway
GO:0007399 - nervous system development
GO:0009897 - external side of plasma membrane
GO:0016167 - glial cell-derived neurotrophic factor receptor activity

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
129091	GDNF Glial cell line-derived neurotrophic factor	2	7	Small-scale	0.778	High
129095	NRTN Neurturin	2	7	Small-scale	0.778	High
129092	PTEN Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	1	0	Small-scale	0.458	High
129094	SYGP1 Ras/Rap GTPase-activating protein SynGAP	1	1	High-throughput	0.445	High
129093	RIMS1 Regulating synaptic membrane exocytosis protein 1	1	0	High-throughput	0.426	High
129090	MYC Myc proto-oncogene protein	1	0	High-throughput	0.249	Low

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Last updated: 15 Jul 2024