Protein: LIPL
Lipoprotein lipase (LPL) (EC 3.1.1.34) (Phospholipase A1) (EC 3.1.1.32)

Gene: LIPL, LPL
Organism: Homo sapiens
Interactions: 53
UniProt ID: P06858

Gene Ontology (top 5):
GO:0001523 - retinoid metabolic process
GO:0004620 - phospholipase activity
GO:0004465 - lipoprotein lipase activity
GO:0004806 - triacylglycerol lipase activity
GO:0005102 - signaling receptor binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

449517

LRP1
Prolow-density lipoprotein receptor-related protein 1

3

7

Small-scale

0.655

High

449502

LIPL
Lipoprotein lipase

1

12

Small-scale

0.647

High

449527

HDBP1
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

2

0

Small-scale

0.614

High

217717

TGON2
Trans-Golgi network integral membrane protein 2

2

2

High-throughput

0.601

High

449520

CUL3
Cullin-3

1

0

High-throughput

0.513

High

421308

A4
Amyloid-beta precursor protein

1

5

High-throughput

0.501

High

449513

VLDLR
Very low-density lipoprotein receptor

1

6

Small-scale

0.501

High

449514

LRP2
Low-density lipoprotein receptor-related protein 2

1

6

Small-scale

0.501

High

449534

SORT
Sortilin

1

1

Small-scale

0.501

High

449535

ANGL4
Angiopoietin-related protein 4

1

2

Small-scale

0.501

High

449545

ANGL3
Angiopoietin-related protein 3

1

2

Small-scale

0.501

High

449506

PTN4
Tyrosine-protein phosphatase non-receptor type 4

1

1

High-throughput

0.494

High

449531

Q8TAS3
PRRG2 protein

1

0

High-throughput

0.493

High

449542

EI2BD
Translation initiation factor eIF2B subunit delta

1

0

High-throughput

0.493

High

449510

NEK4
Serine/threonine-protein kinase Nek4

1

1

High-throughput

0.489

High

449524

APOA5
Apolipoprotein A-V

1

0

Small-scale

0.480

High

449505

CALR
Calreticulin

1

3

Small-scale

0.479

High

449518

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

1

High-throughput

0.479

High

449533

LMF1
Lipase maturation factor 1

1

2

Small-scale

0.479

High

143786

NDKM
Nucleoside diphosphate kinase, mitochondrial

1

1

High-throughput

0.470

High

449504

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.458

High

449507

STAT3
Signal transducer and activator of transcription 3

1

0

Small-scale

0.458

High

449512

RHOA
Transforming protein RhoA

1

0

High-throughput

0.458

High

449537

TOLIP
Toll-interacting protein

1

0

High-throughput

0.458

High

273250

T22D2
TSC22 domain family protein 2

1

1

Small-scale

0.439

High

449519

SQSTM
Sequestosome-1

1

1

High-throughput

0.437

High

449526

TAXB1
Tax1-binding protein 1

1

2

High-throughput

0.437

High

449515

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

0

High-throughput

0.426

High

449525

CSN6
COP9 signalosome complex subunit 6

2

0

High-throughput

0.317

High

449503

CCND1
G1/S-specific cyclin-D1

1

0

High-throughput

0.282

High

449516

RL18A
Large ribosomal subunit protein eL20

1

0

High-throughput

0.282

High

449538

ASCC2
Activating signal cointegrator 1 complex subunit 2

1

0

High-throughput

0.282

High

449540

UBE2Z
Ubiquitin-conjugating enzyme E2 Z

1

0

High-throughput

0.282

High

449541

CE126
Centrosomal protein of 126 kDa

1

0

High-throughput

0.282

High

449544

LC7L2
Putative RNA-binding protein Luc7-like 2

1

0

High-throughput

0.282

High

221229

DCX
Neuronal migration protein doublecortin

1

0

High-throughput

0.279

Low

449511

PLK1
Serine/threonine-protein kinase PLK1

1

0

High-throughput

0.279

Low

449532

EF2KT
Protein-lysine N-methyltransferase EEF2KMT

1

0

High-throughput

0.279

Low

449539

MTRFR
Mitochondrial translation release factor in rescue

1

0

High-throughput

0.279

Low

91519

C9J082
Nephrocystin 1

1

0

High-throughput

0.268

Low

128371

PSMD9
26S proteasome non-ATPase regulatory subunit 9

1

0

High-throughput

0.268

Low

162436

ANM5
Protein arginine N-methyltransferase 5

1

0

High-throughput

0.268

Low

449528

SLN12
Ribonuclease SLFN12

1

0

High-throughput

0.268

Low

449529

VKORL
Vitamin K epoxide reductase complex subunit 1-like protein 1

1

0

High-throughput

0.268

Low

449530

T185A
Transmembrane protein 185A

1

0

High-throughput

0.268

Low

449543

SNX12
Sorting nexin-12

1

0

High-throughput

0.268

Low

449509

EMD
Emerin

1

0

Small-scale

0.251

Low

449508

CEBPD
CCAAT/enhancer-binding protein delta

1

0

Small-scale

0.249

Low

449521

NBR1
Next to BRCA1 gene 1 protein

1

0

High-throughput

0.249

Low

449522

E2F4
Transcription factor E2F4

1

0

High-throughput

0.249

Low

449536

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

0

High-throughput

0.249

Low

449523

SYRM
Probable arginine--tRNA ligase, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025