Protein: GALC
Galactocerebrosidase (GALCERase) (EC 3.2.1.46) (Galactocerebroside beta-galactosidase) (Galactosylceramidase) (Galactosylceramide beta-galactosidase)

Gene: GALC
Organism: Homo sapiens
Interactions: 37
UniProt ID: P54803

Gene Ontology (top 5):
GO:0004336 - galactosylceramidase activity
GO:0005764 - lysosome
GO:0006683 - galactosylceramide catabolic process
GO:0016020 - membrane
GO:0042552 - myelination

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

932420

TMM51
Transmembrane protein 51

3

0

High-throughput

0.638

High

303706

CYTF
Cystatin-F

2

0

High-throughput

0.602

High

534829

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.513

High

548452

MPRI
Cation-independent mannose-6-phosphate receptor

1

0

High-throughput

0.513

High

922412

CLH2
Clathrin heavy chain 2

1

0

High-throughput

0.513

High

932411

CNKR1
Connector enhancer of kinase suppressor of ras 1

1

1

High-throughput

0.489

High

932401

RS7
Small ribosomal subunit protein eS7

1

0

High-throughput

0.458

High

284556

ECI2
Enoyl-CoA delta isomerase 2

1

1

High-throughput

0.445

High

932402

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

1

High-throughput

0.445

High

932416

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

932423

CLC11
C-type lectin domain family 11 member A

4

0

High-throughput

0.360

High

932407

T2H2L
General transcription factor IIH subunit 2-like protein

3

0

High-throughput

0.347

High

932409

OTU6B
Deubiquitinase OTUD6B

3

0

High-throughput

0.347

High

932413

EF2KT
Protein-lysine N-methyltransferase EEF2KMT

3

0

High-throughput

0.347

High

932412

ESS2
Splicing factor ESS-2 homolog

3

0

High-throughput

0.345

High

932417

NCOA5
Nuclear receptor coactivator 5

3

0

High-throughput

0.342

High

932404

IKZF1
DNA-binding protein Ikaros

2

0

High-throughput

0.328

High

932408

TRM11
tRNA

2

0

High-throughput

0.328

High

932415

IER2
Immediate early response gene 2 protein

2

0

High-throughput

0.318

High

932405

OS9
Protein OS-9

1

0

High-throughput

0.279

Low

932406

DNLZ
DNL-type zinc finger protein

1

0

High-throughput

0.279

Low

932410

NEDD1
Protein NEDD1

1

0

High-throughput

0.279

Low

932418

CABP2
Calcium-binding protein 2

1

0

High-throughput

0.279

Low

932419

DJC17
DnaJ homolog subfamily C member 17

1

0

High-throughput

0.279

Low

932422

PNMA2
Paraneoplastic antigen Ma2

1

0

High-throughput

0.279

Low

596010

H12
Histone H1.2

1

0

High-throughput

0.269

Low

932403

TRAF3
TNF receptor-associated factor 3

1

0

Small-scale

0.269

Low

241200

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.249

Low

504722

FBSP1
F-box/SPRY domain-containing protein 1

1

0

High-throughput

0.249

Low

872112

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.249

Low

904500

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.249

Low

932400

H2BFS
Histone H2B type F-S

1

0

High-throughput

0.249

Low

932414

NEUL4
Neuralized-like protein 4

1

0

High-throughput

0.249

Low

932421

THYN1
Thymocyte nuclear protein 1

1

0

High-throughput

0.249

Low

127035

APBB1
Amyloid beta precursor protein binding family B member 1

1

0

High-throughput

0.232

Low

166281

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

0

High-throughput

0.232

Low

877652

SL9A3
Sodium/hydrogen exchanger 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025