Protein: CLCN5
H(+)/Cl(-) exchange transporter 5 (Chloride channel protein 5) (ClC-5) (Chloride transporter ClC-5)

Gene: CLCN5
Organism: Homo sapiens
Interactions: 34
UniProt ID: P51795

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0003014 - renal system process
GO:0005247 - voltage-gated chloride channel activity
GO:0005524 - ATP binding
GO:0005765 - lysosomal membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

907742

CLCN5
H(+)/Cl(-) exchange transporter 5

1

5

Small-scale

0.692

High

907702

CLCN3
H(+)/Cl(-) exchange transporter 3

1

5

High-throughput

0.691

High

127303

LEG8
Galectin-8

3

9

High-throughput

0.667

High

907761

TMM9B
Transmembrane protein 9B

3

6

High-throughput

0.662

High

907762

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

3

6

High-throughput

0.650

High

609628

LEG3
Galectin-3

1

9

High-throughput

0.536

High

901135

RAB7A
Ras-related protein Rab-7a

1

5

High-throughput

0.536

High

907747

LEG9B
Galectin-9B

1

9

High-throughput

0.536

High

907756

FEM1A
Protein fem-1 homolog A

1

1

High-throughput

0.536

High

176600

KIF3B
Kinesin-like protein KIF3B

1

2

Small-scale

0.529

High

230286

CREB3
Cyclic AMP-responsive element-binding protein 3

1

1

High-throughput

0.515

High

907754

DP13B
DCC-interacting protein 13-beta

1

0

High-throughput

0.513

High

907755

VTI1A
Vesicle transport through interaction with t-SNAREs homolog 1A

1

0

High-throughput

0.513

High

256806

H2B1K
Histone H2B type 1-K

1

1

High-throughput

0.479

High

363002

EGFR
Epidermal growth factor receptor

1

3

Small-scale

0.479

High

411614

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.479

High

907745

MTAP
S-methyl-5'-thioadenosine phosphorylase

1

2

High-throughput

0.479

High

907759

RB33B
Ras-related protein Rab-33B

1

1

High-throughput

0.479

High

347589

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

351213

MOT3
Monocarboxylate transporter 3

1

1

High-throughput

0.445

High

388389

B3AT
Band 3 anion transport protein

1

1

High-throughput

0.445

High

907744

ACVR1
Activin receptor type-1

1

1

High-throughput

0.445

High

907746

UT1
Urea transporter 1

1

1

High-throughput

0.445

High

907751

NPAL3
NIPA-like protein 3

1

1

High-throughput

0.445

High

907752

S15A3
Solute carrier family 15 member 3

1

1

High-throughput

0.445

High

907753

S38A9
Neutral amino acid transporter 9

1

1

High-throughput

0.445

High

907758

S46A2
Solute carrier family 46 member 2

1

1

High-throughput

0.445

High

907743

G6PT2
Glucose-6-phosphate exchanger SLC37A1

1

0

High-throughput

0.426

High

907749

MFSD5
Molybdate-anion transporter

1

0

High-throughput

0.426

High

907757

S12A9
Solute carrier family 12 member 9

1

0

High-throughput

0.426

High

907760

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.426

High

907748

EFHC1
EF-hand domain-containing protein 1

1

0

High-throughput

0.249

Low

907750

LTMD1
LETM1 domain-containing protein 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025