Protein: MTAP
S-methyl-5'-thioadenosine phosphorylase (EC 2.4.2.28) (5'-methylthioadenosine phosphorylase) (MTA phosphorylase) (MTAP) (MTAPase)

Gene: MTAP
Organism: Homo sapiens
Interactions: 60
UniProt ID: Q13126

Gene Ontology (top 5):
GO:0004645 - 1,4-alpha-oligoglucan phosphorylase activity
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006139 - nucleobase-containing compound metabolic process
GO:0006166 - purine ribonucleoside salvage

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1050409

UBE3A
Ubiquitin-protein ligase E3A

2

1

Small-scale

0.611

High

1095222

RBM42
RNA-binding protein 42

2

0

High-throughput

0.559

High

1095226

CENPH
Centromere protein H

1

0

High-throughput

0.549

High

1095220

ARI3A
AT-rich interactive domain-containing protein 3A

1

1

High-throughput

0.536

High

1095225

KDM4C
Lysine-specific demethylase 4C

1

1

High-throughput

0.536

High

214255

LYRM1
LYR motif-containing protein 1

1

0

High-throughput

0.518

High

719136

MPIP1
M-phase inducer phosphatase 1

1

0

High-throughput

0.518

High

1029989

RELB
Transcription factor RelB

1

0

High-throughput

0.518

High

1046903

FOLH1
Glutamate carboxypeptidase 2

1

0

High-throughput

0.518

High

1095215

APBP2
Amyloid protein-binding protein 2

1

0

High-throughput

0.513

High

1095224

5NT3A
Cytosolic 5'-nucleotidase 3A

1

0

High-throughput

0.493

High

588586

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.479

High

695343

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

768081

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

872279

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.479

High

888020

MCM2
DNA replication licensing factor MCM2

1

1

High-throughput

0.479

High

907745

CLCN5
H(+)/Cl(-) exchange transporter 5

1

2

High-throughput

0.479

High

934546

TERA
Transitional endoplasmic reticulum ATPase

1

1

Small-scale

0.479

High

1095207

RFA4
Replication protein A 30 kDa subunit

1

2

High-throughput

0.479

High

1095211

ASXL2
Putative Polycomb group protein ASXL2

1

2

High-throughput

0.479

High

1095212

ARI3B
AT-rich interactive domain-containing protein 3B

1

1

High-throughput

0.479

High

1095213

ASXL1
Polycomb group protein ASXL1

1

2

High-throughput

0.479

High

1095214

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.479

High

1095234

MAGD2
Melanoma-associated antigen D2

1

1

High-throughput

0.479

High

315536

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

520000

ANDR
Androgen receptor

1

0

Small-scale

0.458

High

613015

EGR1
Early growth response protein 1

1

0

High-throughput

0.458

High

697099

APEX1
DNA repair nuclease/redox regulator APEX1

1

0

High-throughput

0.458

High

775051

FUS
RNA-binding protein FUS

1

0

High-throughput

0.458

High

974535

SMD2
Small nuclear ribonucleoprotein Sm D2

1

0

High-throughput

0.458

High

1095206

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

0

High-throughput

0.458

High

1095208

CE170
Centrosomal protein of 170 kDa

1

0

High-throughput

0.458

High

1095209

TET5C
Terminal nucleotidyltransferase 5C

1

0

High-throughput

0.458

High

1095219

SCLT1
Sodium channel and clathrin linker 1

1

0

High-throughput

0.458

High

1095233

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1095236

DC1L1
Cytoplasmic dynein 1 light intermediate chain 1

1

0

High-throughput

0.458

High

330144

VENTX
Homeobox protein VENTX

1

1

High-throughput

0.445

High

429813

JUN
Transcription factor Jun

1

1

High-throughput

0.445

High

1095229

DDX28
Probable ATP-dependent RNA helicase DDX28

1

1

High-throughput

0.445

High

353301

AGR2
Anterior gradient protein 2 homolog

1

1

High-throughput

0.437

High

907706

CLCN3
H(+)/Cl(-) exchange transporter 3

1

2

High-throughput

0.437

High

907738

CLCN4
H(+)/Cl(-) exchange transporter 4

1

2

High-throughput

0.437

High

1086525

TROP
Trophinin

1

1

High-throughput

0.437

High

1095210

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

1095217

EFHD2
EF-hand domain-containing protein D2

1

1

Small-scale

0.437

High

1095223

ASXL3
Putative Polycomb group protein ASXL3

1

3

High-throughput

0.437

High

142332

PEX7
Peroxisomal targeting signal 2 receptor

1

0

High-throughput

0.426

High

404778

PRIO
Major prion protein

1

0

High-throughput

0.426

High

1095216

RBPMS
RNA-binding protein with multiple splicing

1

0

High-throughput

0.426

High

1095227

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

0

High-throughput

0.426

High

1095231

EMC3
ER membrane protein complex subunit 3

2

0

High-throughput

0.316

High

1041036

CAV1
Caveolin-1

2

0

High-throughput

0.298

High

1095221

SH3G3
Endophilin-A3

2

0

High-throughput

0.298

High

892102

KLK7
Kallikrein-7

1

0

High-throughput

0.279

Low

105853

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

1095228

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1095230

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.249

Low

1095232

ABCF2
ATP-binding cassette sub-family F member 2

1

0

High-throughput

0.249

Low

1095218

NEUL4
Neuralized-like protein 4

1

0

High-throughput

0.232

Low

1095235

GPSM3
G-protein-signaling modulator 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025