Protein: RIOX1
Ribosomal oxygenase 1 (60S ribosomal protein L8 histidine hydroxylase) (Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66) (EC 1.14.11.27, EC 1.14.11.79) (Myc-associated protein with JmjC domain) (Nucleolar protein 66) (hsNO66) (Ribosomal oxygenase NO66) (ROX)

Gene: RIOX1
Organism: Homo sapiens
Interactions: 68
UniProt ID: Q9H6W3

Gene Ontology (top 5):
GO:0005506 - iron ion binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0006282 - regulation of DNA repair

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1435223

RIOX1
Ribosomal oxygenase 1

1

1

Small-scale

0.647

High

986213

RL8
Large ribosomal subunit protein uL2

2

1

Small-scale

0.619

High

373155

MYC
Myc proto-oncogene protein

2

1

Small-scale

0.584

High

141112

NOP56
Nucleolar protein 56

1

1

High-throughput

0.536

High

191804

MAGB2
Melanoma-associated antigen B2

1

1

High-throughput

0.536

High

288770

NPM3
Nucleoplasmin-3

1

3

High-throughput

0.536

High

447449

NPM
Nucleophosmin

1

3

High-throughput

0.536

High

686433

RL13
Large ribosomal subunit protein eL13

1

1

High-throughput

0.536

High

693979

RL10
Large ribosomal subunit protein uL16

1

1

High-throughput

0.536

High

785455

RL4
Large ribosomal subunit protein uL4

1

1

High-throughput

0.536

High

833192

MNDA
Myeloid cell nuclear differentiation antigen

1

1

High-throughput

0.536

High

1027759

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

2

High-throughput

0.536

High

458485

ADRB2
Beta-2 adrenergic receptor

1

0

High-throughput

0.518

High

428985

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.513

High

521939

H14
Histone H1.4

1

0

High-throughput

0.513

High

766855

PHB1
Prohibitin 1

1

0

High-throughput

0.513

High

854302

KI67
Proliferation marker protein Ki-67

1

0

High-throughput

0.513

High

975944

RL7A
Large ribosomal subunit protein eL8

1

0

High-throughput

0.513

High

1092717

AF1Q
Protein AF1q

1

0

High-throughput

0.513

High

1288254

LYRIC
Protein LYRIC

1

0

High-throughput

0.513

High

1416118

RBM4
RNA-binding protein 4

1

0

High-throughput

0.513

High

1435224

UBP42
Ubiquitin carboxyl-terminal hydrolase 42

1

0

High-throughput

0.513

High

1435232

CHCH2
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

1

0

High-throughput

0.513

High

898821

RL14
Large ribosomal subunit protein eL14

1

1

High-throughput

0.489

High

248348

HBP1
HMG box-containing protein 1

1

1

High-throughput

0.479

High

401483

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

810382

RL3
Large ribosomal subunit protein uL3

1

1

High-throughput

0.479

High

979244

RS6
Small ribosomal subunit protein eS6

1

1

High-throughput

0.479

High

1138065

TNIP1
TNFAIP3-interacting protein 1

1

2

High-throughput

0.479

High

1367280

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

1435228

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

129434

MEN1
Menin

1

0

High-throughput

0.458

High

194346

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.458

High

242937

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

831437

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

937914

FOXA1
Hepatocyte nuclear factor 3-alpha

1

0

High-throughput

0.458

High

1024848

VIGLN
Vigilin

1

0

High-throughput

0.458

High

1045770

TF65
Transcription factor p65

1

0

High-throughput

0.458

High

1114310

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1155775

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

1194382

LARP7
La-related protein 7

1

0

High-throughput

0.458

High

1238480

ZN746
Zinc finger protein 746

1

0

High-throughput

0.458

High

1352757

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

1371289

KAT5
Histone acetyltransferase KAT5

1

0

Small-scale

0.458

High

1410371

MEP50
Methylosome protein WDR77

1

0

High-throughput

0.458

High

1435227

AKIP
Small ribosomal subunit protein mS38

1

0

High-throughput

0.458

High

1435229

PPIE
Peptidyl-prolyl cis-trans isomerase E

1

0

High-throughput

0.458

High

1435231

TRRAP
Transformation/transcription domain-associated protein

1

0

Small-scale

0.458

High

1414239

ZSA5A
Zinc finger and SCAN domain-containing protein 5A

1

1

High-throughput

0.445

High

640289

EPHA1
Ephrin type-A receptor 1

1

1

High-throughput

0.437

High

1199699

KLH22
Kelch-like protein 22

1

0

High-throughput

0.426

High

275384

NDUS7
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

1

0

High-throughput

0.279

Low

474988

VIME
Vimentin

1

0

High-throughput

0.279

Low

951433

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.279

Low

1094119

RM28
Large ribosomal subunit protein bL28m

1

0

High-throughput

0.279

Low

1106236

MYO9B
Unconventional myosin-IXb

1

0

High-throughput

0.279

Low

1312763

RM41
Large ribosomal subunit protein mL41

1

0

High-throughput

0.279

Low

1382299

RM24
Large ribosomal subunit protein uL24m

1

0

High-throughput

0.279

Low

1435225

SDF2L
Stromal cell-derived factor 2-like protein 1

1

0

High-throughput

0.279

Low

1435226

RM47
Large ribosomal subunit protein uL29m

1

0

High-throughput

0.279

Low

1435230

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.279

Low

1433895

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

213250

CP110
Centriolar coiled-coil protein of 110 kDa

1

0

High-throughput

0.232

Low

1063077

S20A2
Sodium-dependent phosphate transporter 2

1

0

High-throughput

0.232

Low

1313841

S15A3
Solute carrier family 15 member 3

1

0

High-throughput

0.232

Low

1332339

NLS1
Sodium-dependent lysophosphatidylcholine symporter 1

1

0

High-throughput

0.232

Low

1352986

CE192
Centrosomal protein of 192 kDa

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025