Protein: UBE2U
Ubiquitin-conjugating enzyme E2 U (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme U) (Ubiquitin carrier protein U) (Ubiquitin-protein ligase U)

Gene: UBE2U
Organism: Homo sapiens
Interactions: 145
UniProt ID: Q5VVX9

Gene Ontology (top 5):
GO:0000209 - protein polyubiquitination
GO:0005524 - ATP binding
GO:0006281 - DNA repair
GO:0033503 - HULC complex
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1023286

TRI32
E3 ubiquitin-protein ligase TRIM32

2

20

High-throughput

0.834

High

1138882

R144B
E3 ubiquitin-protein ligase RNF144B

2

20

High-throughput

0.815

High

182793

R113A
E3 ubiquitin-protein ligase RNF113A

1

2

High-throughput

0.698

High

262178

TRIM3
Tripartite motif-containing protein 3

1

20

High-throughput

0.698

High

668750

PML
Protein PML

1

20

High-throughput

0.698

High

962820

MDM2
E3 ubiquitin-protein ligase Mdm2

1

14

High-throughput

0.698

High

1029521

TIF1B
Transcription intermediary factor 1-beta

1

20

High-throughput

0.698

High

1138888

DZIP3
E3 ubiquitin-protein ligase DZIP3

1

20

High-throughput

0.698

High

1138892

ZSWM2
E3 ubiquitin-protein ligase ZSWIM2

1

20

High-throughput

0.698

High

1138894

RN139
E3 ubiquitin-protein ligase RNF139

1

20

High-throughput

0.698

High

1138898

MUL1
Mitochondrial ubiquitin ligase activator of NFKB 1

1

20

High-throughput

0.698

High

1138899

RN166
E3 ubiquitin-protein ligase RNF166

1

20

High-throughput

0.698

High

1138902

RN125
E3 ubiquitin-protein ligase RNF125

1

20

High-throughput

0.698

High

1138916

TRI34
E3 ubiquitin-protein ligase TRIM34

1

20

High-throughput

0.698

High

1138917

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

20

High-throughput

0.698

High

1138920

TRIM5
Tripartite motif-containing protein 5

1

20

High-throughput

0.698

High

1138921

TRIM2
Tripartite motif-containing protein 2

1

20

High-throughput

0.698

High

1138923

RNF41
E3 ubiquitin-protein ligase NRDP1

1

20

High-throughput

0.698

High

1138927

RNF14
E3 ubiquitin-protein ligase RNF14

1

20

High-throughput

0.698

High

1138933

RN114
E3 ubiquitin-protein ligase RNF114

1

20

High-throughput

0.698

High

607087

UBA1
Ubiquitin-like modifier-activating enzyme 1

1

20

Small-scale

0.647

High

718404

PCGF2
Polycomb group RING finger protein 2

1

20

High-throughput

0.625

High

734651

TRI23
E3 ubiquitin-protein ligase TRIM23

1

18

High-throughput

0.625

High

1129174

RNFT1
E3 ubiquitin-protein ligase RNFT1

1

20

High-throughput

0.625

High

1138881

TRI65
E3 ubiquitin-protein ligase TRIM65

1

20

High-throughput

0.625

High

1138883

TRI46
Tripartite motif-containing protein 46

1

20

High-throughput

0.625

High

1138884

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

20

High-throughput

0.625

High

1138885

TRI74
Tripartite motif-containing protein 74

1

20

High-throughput

0.625

High

1138887

DTX1
E3 ubiquitin-protein ligase DTX1

1

20

High-throughput

0.625

High

1138889

MIB1
E3 ubiquitin-protein ligase MIB1

1

8

High-throughput

0.625

High

1138891

RNF10
E3 ubiquitin-protein ligase RNF10

1

20

High-throughput

0.625

High

1138893

PJA1
E3 ubiquitin-protein ligase Praja-1

1

20

High-throughput

0.625

High

1138900

MIB2
E3 ubiquitin-protein ligase MIB2

1

8

High-throughput

0.625

High

1138901

RNF25
E3 ubiquitin-protein ligase RNF25

1

15

High-throughput

0.625

High

1138904

RN170
E3 ubiquitin-protein ligase RNF170

1

2

High-throughput

0.625

High

1138905

TRI47
E3 ubiquitin-protein ligase TRIM47

1

20

High-throughput

0.625

High

1138906

RING2
E3 ubiquitin-protein ligase RING2

1

20

High-throughput

0.625

High

1138910

RNF5
E3 ubiquitin-protein ligase RNF5

1

20

High-throughput

0.625

High

1138911

PCGF1
Polycomb group RING finger protein 1

1

20

High-throughput

0.625

High

1138912

TRAIP
E3 ubiquitin-protein ligase TRAIP

1

8

High-throughput

0.625

High

1138914

RNF26
E3 ubiquitin-protein ligase RNF26

1

20

High-throughput

0.625

High

1138915

PCGF6
Polycomb group RING finger protein 6

1

20

High-throughput

0.625

High

1138918

TRI54
Tripartite motif-containing protein 54

1

20

High-throughput

0.625

High

1138919

TRI15
E3 ubiquitin-protein ligase TRIM15

1

20

High-throughput

0.625

High

1138922

VPS11
Vacuolar protein sorting-associated protein 11 homolog

1

5

High-throughput

0.625

High

1138924

APC11
Anaphase-promoting complex subunit 11

1

20

High-throughput

0.625

High

1138926

RN181
E3 ubiquitin-protein ligase RNF181

1

20

High-throughput

0.625

High

1138930

RN150
RING finger protein 150

1

20

High-throughput

0.625

High

1138931

TRI35
E3 ubiquitin-protein ligase TRIM35

1

20

High-throughput

0.625

High

1138932

RNF11
RING finger protein 11

1

20

High-throughput

0.625

High

610432

CBL
E3 ubiquitin-protein ligase CBL

1

12

Small-scale

0.621

High

1023479

MKRN3
Probable E3 ubiquitin-protein ligase makorin-3

1

14

High-throughput

0.621

High

1138877

RN213
E3 ubiquitin-protein ligase RNF213

1

2

Small-scale

0.621

High

921605

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

5

High-throughput

0.594

High

1138907

CGRF1
Cell growth regulator with RING finger domain protein 1

1

0

High-throughput

0.584

High

994944

GOGA2
Golgin subfamily A member 2

2

1

High-throughput

0.584

High

1138890

R113B
RING finger protein 113B

1

2

High-throughput

0.555

High

1138897

TRI63
E3 ubiquitin-protein ligase TRIM63

1

20

High-throughput

0.555

High

1138928

TRIM1
Probable E3 ubiquitin-protein ligase MID2

1

20

High-throughput

0.555

High

135028

TRI38
E3 ubiquitin-protein ligase TRIM38

1

20

High-throughput

0.541

High

1138878

TRI68
E3 ubiquitin-protein ligase TRIM68

1

20

High-throughput

0.541

High

1138908

BARD1
BRCA1-associated RING domain protein 1

1

9

High-throughput

0.541

High

1138925

BFAR
Bifunctional apoptosis regulator

1

20

High-throughput

0.541

High

1128568

Q5JVY0
RING-type E3 ubiquitin transferase

1

20

High-throughput

0.528

High

1138879

Q6GX22
RING-type E3 ubiquitin transferase

1

20

High-throughput

0.528

High

1138880

Q6NR77
Ring finger protein 28

1

20

High-throughput

0.528

High

772006

VHL
von Hippel-Lindau disease tumor suppressor

1

3

High-throughput

0.515

High

170390

TIF1A
Transcription intermediary factor 1-alpha

1

20

High-throughput

0.494

High

301864

TRI37
E3 ubiquitin-protein ligase TRIM37

1

20

High-throughput

0.494

High

536873

TRI27
Zinc finger protein RFP

1

20

High-throughput

0.494

High

833141

VPS41
Vacuolar protein sorting-associated protein 41 homolog

1

5

High-throughput

0.494

High

1138886

CAPS2
Calcium-dependent secretion activator 2

1

6

High-throughput

0.494

High

1138895

KAT6A
Histone acetyltransferase KAT6A

1

2

High-throughput

0.494

High

60592

VP37C
Vacuolar protein sorting-associated protein 37C

1

2

High-throughput

0.489

High

82421

IGLL5
Immunoglobulin lambda-like polypeptide 5

1

8

High-throughput

0.489

High

341146

THRB
Prothrombin

1

6

High-throughput

0.489

High

341211

HPT
Haptoglobin

1

3

High-throughput

0.489

High

341384

PLMN
Plasminogen

1

5

High-throughput

0.489

High

341588

CFAB
Complement factor B

1

5

High-throughput

0.489

High

344119

ANT3
Antithrombin-III

1

6

High-throughput

0.489

High

344199

A1AT
Alpha-1-antitrypsin

1

6

High-throughput

0.489

High

344301

AACT
Alpha-1-antichymotrypsin

1

6

High-throughput

0.489

High

344373

ANGT
Angiotensinogen

1

7

High-throughput

0.489

High

344502

A2MG
Alpha-2-macroglobulin

1

3

High-throughput

0.489

High

344677

CO3
Complement C3

1

3

High-throughput

0.489

High

344762

CO5
Complement C5

1

3

High-throughput

0.489

High

345189

KNG1
Kininogen-1

1

2

High-throughput

0.489

High

361353

APOA1
Apolipoprotein A-I

1

1

High-throughput

0.489

High

361760

FIBA
Fibrinogen alpha chain [Cleaved into: Fibrinopeptide A; Fibrinogen alpha chain]

1

2

High-throughput

0.489

High

361876

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

1

2

High-throughput

0.489

High

361999

FIBG
Fibrinogen gamma chain

1

2

High-throughput

0.489

High

362651

A2GL
Leucine-rich alpha-2-glycoprotein

1

1

High-throughput

0.489

High

363203

FINC
Fibronectin

1

2

High-throughput

0.489

High

363440

A1AG1
Alpha-1-acid glycoprotein 1

1

1

High-throughput

0.489

High

363519

FETUA
Alpha-2-HS-glycoprotein

1

2

High-throughput

0.489

High

363605

TTHY
Transthyretin

1

1

High-throughput

0.489

High

363815

ALBU
Albumin

1

1

High-throughput

0.489

High

364013

VTDB
Vitamin D-binding protein

1

1

High-throughput

0.489

High

364791

HEMO
Hemopexin

1

1

High-throughput

0.489

High

372958

C4BPA
C4b-binding protein alpha chain

1

2

High-throughput

0.489

High

373027

VTNC
Vitronectin

1

1

High-throughput

0.489

High

378833

HRG
Histidine-rich glycoprotein

1

3

High-throughput

0.489

High

380212

A1BG
Alpha-1B-glycoprotein

1

2

High-throughput

0.489

High

397692

IC1
Plasma protease C1 inhibitor

1

9

High-throughput

0.489

High

403564

HEP2
Heparin cofactor 2

1

6

High-throughput

0.489

High

437221

CBG
Corticosteroid-binding globulin

1

6

High-throughput

0.489

High

441743

CFAH
Complement factor H

1

2

High-throughput

0.489

High

443578

VIME
Vimentin

1

2

High-throughput

0.489

High

444036

A2AP
Alpha-2-antiplasmin

1

9

High-throughput

0.489

High

483514

SAA2
Serum amyloid A-2 protein

1

1

High-throughput

0.489

High

586101

A1AG2
Alpha-1-acid glycoprotein 2

1

1

High-throughput

0.489

High

587350

ITIH2
Inter-alpha-trypsin inhibitor heavy chain H2

1

2

High-throughput

0.489

High

587401

ITIH1
Inter-alpha-trypsin inhibitor heavy chain H1

1

2

High-throughput

0.489

High

667977

SPB3
Serpin B3

1

5

High-throughput

0.489

High

724161

SAA4
Serum amyloid A-4 protein

1

1

High-throughput

0.489

High

738922

PEDF
Pigment epithelium-derived factor

1

9

High-throughput

0.489

High

820323

SPB4
Serpin B4

1

5

High-throughput

0.489

High

945682

NGAL
Neutrophil gelatinase-associated lipocalin

1

2

High-throughput

0.489

High

1056179

ITIH4
Inter-alpha-trypsin inhibitor heavy chain H4

1

2

High-throughput

0.489

High

1138896

KLK6
Kallikrein-6

1

1

High-throughput

0.489

High

445432

RSSA
Small ribosomal subunit protein uS2

1

1

High-throughput

0.417

High

353527

IGKC
Immunoglobulin kappa constant

1

7

High-throughput

0.407

High

353680

IGHG1
Immunoglobulin heavy constant gamma 1

1

9

High-throughput

0.407

High

353783

IGHG2
Immunoglobulin heavy constant gamma 2

1

10

High-throughput

0.407

High

353850

IGHG3
Immunoglobulin heavy constant gamma 3

1

9

High-throughput

0.407

High

353883

IGHG4
Immunoglobulin heavy constant gamma 4

1

11

High-throughput

0.407

High

353947

IGHM
Immunoglobulin heavy constant mu

1

9

High-throughput

0.407

High

354075

IGHA1
Immunoglobulin heavy constant alpha 1

1

7

High-throughput

0.407

High

416898

APOA4
Apolipoprotein A-IV

1

1

High-throughput

0.407

High

469905

CO4B
Complement C4-B

1

3

High-throughput

0.407

High

474415

IGLC6
Immunoglobulin lambda constant 6

1

8

High-throughput

0.407

High

1138929

VPS28
Vacuolar protein sorting-associated protein 28 homolog

3

0

High-throughput

0.347

High

1138903

MB12A
Multivesicular body subunit 12A

2

0

High-throughput

0.328

High

1138913

RNF17
RING finger protein 17

1

0

High-throughput

0.282

High

336776

CERU
Ceruloplasmin

1

0

High-throughput

0.279

Low

361578

APOA2
Apolipoprotein A-II

1

0

High-throughput

0.279

Low

362432

SAMP
Serum amyloid P-component

1

0

High-throughput

0.279

Low

362533

C1QB
Complement C1q subcomponent subunit B

1

0

High-throughput

0.279

Low

362613

CO9
Complement component C9 [Cleaved into: Complement component C9a; Complement component C9b]

1

0

High-throughput

0.279

Low

363386

RET4
Retinol-binding protein 4

1

0

High-throughput

0.279

Low

364564

TRFE
Serotransferrin

1

0

High-throughput

0.279

Low

376470

APOB
Apolipoprotein B-100

1

0

High-throughput

0.279

Low

646487

PON1
Serum paraoxonase/arylesterase 1

1

0

High-throughput

0.279

Low

935789

HBB
Hemoglobin subunit beta

1

0

High-throughput

0.279

Low

1138909

TS101
Tumor susceptibility gene 101 protein

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024