HitPredict

Interactor 1: CLH (P22137)
Clathrin heavy chain
Gene: CHC1

Interactor 2: SWA2 (Q06677)
Auxilin-like clathrin uncoating factor SWA2 (Bud site selection protein 24) (DnaJ-related protein SWA2) (J protein SWA2) (Synthetic lethal with ARF1 protein 2)
Gene: SWA2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.677

Property	Details
Experiments	11146663, 16687570, 22615397, 18467557
Identification Methods	affinity chromatography technology, pull down, protein complementation assay, dihydrofolate reductase reconstruction
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1653 Sc			1 668
+	Hs
		161648 CLH1_HUMAN (4-1648): 0: 2909: 49.76		GAK_HUMAN (525-664): 1.03e-47: 183: 27.59
+	Bt
		836912 CLH1_BOVIN (4-1648): 0: 2909: 49.76		AUXI_BOVIN (490-664): 1.07e-42: 167: 23.76
+	Hs
		253739 CLH1_HUMAN (4-1648): 0: 2909: 49.76		AUXI_HUMAN (500-664): 2.72e-41: 163: 23.98
+	Hs
		684637 CLH1_HUMAN (4-1648): 0: 2909: 49.76		STIP1_HUMAN (364-644): 2.25e-16: 84.8: 12.10
+	Hs
		161639 CLH2_HUMAN (4-1635): 0: 2773: 48.90		GAK_HUMAN (525-664): 1.03e-47: 183: 27.59
+	Hs
		253737 CLH2_HUMAN (4-1635): 0: 2773: 48.90		AUXI_HUMAN (500-664): 2.72e-41: 163: 23.98
+	Ce
		90245 CLH_CAEEL (4-1650): 0: 2715: 46.52		D7SFQ6_CAEEL (485-664): 5.44e-33: 134: 19.25
+	Sc
		549700 CLH_YEAST (1-1653): 0: 2506: 100.00		STI1_YEAST (309-630): 1.07e-13: 76.3: 12.42