HitPredict

Interactor 1: DAB2 (P98078)
Disabled homolog 2 (Adaptor molecule disabled-2) (Differentially expressed in ovarian carcinoma 2) (DOC-2) (Mitogen-responsive phosphoprotein)
Gene: DAB2

Interactor 2: DVL3 (Q61062)
Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3)
Gene: DVL3

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	12805222
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~PID
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 766 Mm			1 716
+	Hs
		1022188 DAB2_HUMAN (1-766): 9.44e-78: 267: 81.63		DVL3_HUMAN (1-716): 6.2e-160: 480: 99.02
+	Mm
		1022122 DAB2_MOUSE (1-766): 2.91e-93: 309: 100.00		DVL2_MOUSE (3-716): 1.7e-124: 389: 63.77
+	Hs
		159336 DAB2_HUMAN (1-766): 9.44e-78: 267: 81.63		DVL1_HUMAN (1-716): 2.23e-140: 429: 62.83
+	Hs
		159608 DAB2_HUMAN (1-766): 9.44e-78: 267: 81.63		DVL2_HUMAN (3-716): 3.12e-120: 378: 64.90
+	Hs
		159901 GULP1_HUMAN (23-319): 5.36e-59: 204: 21.07		DVL2_HUMAN (3-716): 3.12e-120: 378: 64.90
+	Hs
		159566 NUMB_HUMAN (20-678): 7.45e-47: 179: 14.79		DVL2_HUMAN (3-716): 3.12e-120: 378: 64.90
+	Mm
		1022135 DAB2_MOUSE (1-766): 2.91e-93: 309: 100.00		PARD3_MOUSE (119-419): 2.8e-15: 82.3: 16.01
+	Mm
		1223631 Q8BZM2_MOUSE (2-243): 3.91e-47: 176: 17.89		DLG4_MOUSE (93-627): 1.38e-51: 193: 13.92
+	Mm
		1223615 ANS1B_MOUSE (2-243): 4.98e-43: 170: 17.89		DLG4_MOUSE (93-627): 1.38e-51: 193: 13.92
+	Mm
		948038 ANS1A_MOUSE (1-248): 1.53e-40: 163: 19.84		DLG4_MOUSE (93-627): 1.38e-51: 193: 13.92
+	Mm
		1223664 DP13A_MOUSE (20-253): 6.58e-37: 150: 13.93		DLG4_MOUSE (93-627): 1.38e-51: 193: 13.92
+	Hs
		889313 NUMB_HUMAN (20-678): 7.45e-47: 179: 14.79		PARD3_HUMAN (84-645): 2.18e-41: 164: 15.01
+	Hs
		1006118 DP13A_HUMAN (20-246): 6.78e-36: 146: 12.66		DLG4_HUMAN (93-627): 7.11e-51: 191: 13.74
+	Hs
		889311 NUMB_HUMAN (20-678): 7.45e-47: 179: 14.79		LNX1_HUMAN (2-330): 3.11e-18: 91.5: 14.80
+	Mm
		1362346 NUMB_MOUSE (20-678): 3.03e-44: 171: 12.57		LNX2_MOUSE (5-331): 1.7e-19: 95.3: 13.04
+	Hs
		889307 NUMB_HUMAN (20-678): 7.45e-47: 179: 14.79		LNX2_HUMAN (145-501): 3.18e-16: 84.9: 13.89
+	Mm
		266822 NUMB_MOUSE (20-678): 3.03e-44: 171: 12.57		LNX1_MOUSE (8-330): 2.13e-18: 91.8: 14.86
+	Mm
		148518 NUMBL_MOUSE (34-518): 3.61e-43: 167: 15.03		LNX2_MOUSE (5-331): 1.7e-19: 95.3: 13.04
+	Hs
		286394 DAB1_HUMAN (11-633): 9.61e-39: 154: 22.95		LNX1_HUMAN (2-330): 3.11e-18: 91.5: 14.80
+	Hs
		269765 CAPON_HUMAN (21-283): 2.55e-39: 154: 14.58		SCRIB_HUMAN (240-454): 7.89e-17: 87.5: 17.27