Protein: HRQ1
ATP-dependent helicase HRQ1 (EC 5.6.2.4) (Homologous to recQ protein 1)

Gene: HRQ1
Organism: Saccharomyces cerevisiae S288C
Interactions: 92
UniProt ID: Q05549

Gene Ontology (top 5):
GO:0003697 - single-stranded DNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0006289 - nucleotide-excision repair
GO:0008047 - enzyme activator activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

632596

DBP3
ATP-dependent RNA helicase DBP3

1

17

Small-scale

0.618

High

734478

BTAF1
TATA-binding protein-associated factor MOT1

1

20

Small-scale

0.618

High

779159

DHR2
Probable ATP-dependent RNA helicase DHR2

1

18

Small-scale

0.618

High

793532

MAK5
ATP-dependent RNA helicase MAK5

1

17

Small-scale

0.618

High

852601

ROK1
ATP-dependent RNA helicase ROK1

1

17

Small-scale

0.618

High

1018324

CTR9
RNA polymerase-associated protein CTR9

1

6

Small-scale

0.618

High

1046030

DHR1
Probable ATP-dependent RNA helicase DHR1

1

20

Small-scale

0.618

High

1047278

ERB1
Ribosome biogenesis protein ERB1

1

15

Small-scale

0.618

High

1051611

SGD1
Suppressor of glycerol defect protein 1

1

9

Small-scale

0.618

High

1051613

DBP9
ATP-dependent RNA helicase DBP9

1

17

Small-scale

0.618

High

1051626

DBP10
ATP-dependent RNA helicase DBP10

1

17

Small-scale

0.618

High

513578

RL1A
Large ribosomal subunit protein uL1A

1

7

Small-scale

0.553

High

738258

NHP2
H/ACA ribonucleoprotein complex subunit NHP2

1

7

Small-scale

0.553

High

803936

CIC1
Proteasome-interacting protein CIC1

1

3

Small-scale

0.553

High

668297

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

0

High-throughput

0.493

High

720950

PSO2
DNA cross-link repair protein PSO2/SNM1

1

0

Small-scale

0.480

High

382348

H4
Histone H4

1

8

Small-scale

0.479

High

419506

H2A1
Histone H2A.1

1

6

Small-scale

0.479

High

513414

RL23B
Large ribosomal subunit protein uL14B

1

2

Small-scale

0.479

High

632212

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

2

Small-scale

0.479

High

692624

NSR1
Nuclear localization sequence-binding protein

1

20

Small-scale

0.479

High

708190

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.479

High

734835

SRP21
Signal recognition particle subunit SRP21

1

1

Small-scale

0.479

High

779193

NDK
Nucleoside diphosphate kinase

1

1

High-throughput

0.479

High

800974

RFC3
Replication factor C subunit 3

1

6

Small-scale

0.479

High

801924

KSP1
Serine/threonine-protein kinase KSP1

1

8

Small-scale

0.479

High

807147

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

2

Small-scale

0.479

High

808481

SRP14
Signal recognition particle subunit SRP14

1

1

Small-scale

0.479

High

814386

NOC2
Nucleolar complex protein 2

1

1

Small-scale

0.479

High

816903

NUG1
Nuclear GTP-binding protein NUG1

1

6

Small-scale

0.479

High

818275

NSA2
Ribosome biogenesis protein NSA2

1

1

Small-scale

0.479

High

822973

RFC4
Replication factor C subunit 4

1

7

Small-scale

0.479

High

826837

DSN1
Kinetochore-associated protein DSN1

1

2

High-throughput

0.479

High

919557

SDA1
Protein SDA1

1

1

Small-scale

0.479

High

924630

NAT10
RNA cytidine acetyltransferase

1

1

Small-scale

0.479

High

1028609

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

1

Small-scale

0.479

High

1044748

SCC2
Sister chromatid cohesion protein 2

1

3

High-throughput

0.479

High

1045168

SIZ1
E3 SUMO-protein ligase SIZ1

1

4

High-throughput

0.479

High

1051610

MRD1
Multiple RNA-binding domain-containing protein 1

1

10

Small-scale

0.479

High

1051612

FKBP4
FK506-binding protein 4

1

2

Small-scale

0.479

High

1051615

CDC73
Cell division control protein 73

1

1

Small-scale

0.479

High

1051616

TSR1
Ribosome biogenesis protein TSR1

1

4

Small-scale

0.479

High

1051617

RIX7
Ribosome biogenesis ATPase RIX7

1

8

Small-scale

0.479

High

1051621

BMS1
Ribosome biogenesis protein BMS1

1

4

Small-scale

0.479

High

1051622

RIO1
Serine/threonine-protein kinase RIO1

1

10

High-throughput

0.479

High

1051625

GIN4
Serine/threonine-protein kinase GIN4

1

3

Small-scale

0.479

High

1051627

NOP56
Nucleolar protein 56

1

3

Small-scale

0.479

High

1051629

RRP12
Ribosomal RNA-processing protein 12

1

2

Small-scale

0.479

High

575261

RAD4
DNA repair protein RAD4

1

0

Small-scale

0.460

High

758257

URB1
Nucleolar pre-ribosomal-associated protein 1

1

0

Small-scale

0.458

High

794763

RTG3
Retrograde regulation protein 3

1

0

Small-scale

0.458

High

800271

LEO1
RNA polymerase-associated protein LEO1

1

0

Small-scale

0.458

High

806571

UTP9
U3 small nucleolar RNA-associated protein 9

1

0

Small-scale

0.458

High

865170

MPP10
U3 small nucleolar RNA-associated protein MPP10

1

0

Small-scale

0.458

High

918821

UTP22
U3 small nucleolar RNA-associated protein 22

1

0

Small-scale

0.458

High

1046171

PDS5
Sister chromatid cohesion protein PDS5

1

0

Small-scale

0.458

High

1051614

ESF1
Pre-rRNA-processing protein ESF1

1

0

Small-scale

0.458

High

1051618

NOP8
60S ribosome subunit biogenesis protein NOP8

1

0

Small-scale

0.458

High

1051623

PUS1
tRNA pseudouridine synthase 1

1

0

Small-scale

0.458

High

864749

BBC1
Myosin tail region-interacting protein MTI1

1

11

High-throughput

0.457

High

393332

HSP82
ATP-dependent molecular chaperone HSP82

1

12

High-throughput

0.445

High

525157

HSP71
Heat shock protein SSA1

1

18

High-throughput

0.445

High

546279

SSB1
Ribosome-associated molecular chaperone SSB1

1

18

High-throughput

0.445

High

676350

MAS5
Mitochondrial protein import protein MAS5

1

11

High-throughput

0.445

High

742396

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

804457

SSZ1
Ribosome-associated complex subunit SSZ1

1

11

High-throughput

0.445

High

455264

RS19A
Small ribosomal subunit protein eS19A

1

5

Small-scale

0.437

High

502674

RS25B
Small ribosomal subunit protein eS25B

1

2

Small-scale

0.437

High

511490

RL43B
Large ribosomal subunit protein eL43B

1

2

Small-scale

0.437

High

512654

RS6A
Small ribosomal subunit protein eS6A

1

6

Small-scale

0.437

High

513220

RS8A
Small ribosomal subunit protein eS8A

1

2

Small-scale

0.437

High

514368

RL12B
Large ribosomal subunit protein uL11B

1

2

Small-scale

0.437

High

671711

SCJ1
DnaJ-related protein SCJ1

1

7

Small-scale

0.437

High

700293

GAR1
H/ACA ribonucleoprotein complex subunit GAR1

1

2

Small-scale

0.437

High

720937

SEC1
Protein transport protein SEC1

1

4

Small-scale

0.437

High

738431

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

2

Small-scale

0.437

High

751487

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

4

Small-scale

0.437

High

814042

IF2P
Eukaryotic translation initiation factor 5B

1

4

Small-scale

0.437

High

827609

RLP7
Ribosome biogenesis protein RLP7

1

4

Small-scale

0.437

High

844612

UTP10
U3 small nucleolar RNA-associated protein 10

1

1

Small-scale

0.437

High

1035330

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

18

High-throughput

0.437

High

1051620

AP3D
AP-3 complex subunit delta

1

5

Small-scale

0.437

High

1051624

UTP12
U3 small nucleolar RNA-associated protein 12

1

17

Small-scale

0.437

High

1051628

AIR2
Protein AIR2

1

6

Small-scale

0.437

High

405145

LEU3
3-isopropylmalate dehydrogenase

1

0

Small-scale

0.249

Low

671391

PHO84
Inorganic phosphate transporter PHO84

1

0

Small-scale

0.249

Low

804663

SSF1
Ribosome biogenesis protein SSF1

1

0

Small-scale

0.249

Low

808308

RRP8
25S rRNA

1

0

Small-scale

0.249

Low

825082

RRT14
Regulator of rDNA transcription protein 14

1

0

Small-scale

0.249

Low

850752

COPD
Coatomer subunit delta

1

0

Small-scale

0.249

Low

871054

NOL10
Ribosome biogenesis protein ENP2

1

0

Small-scale

0.249

Low

1051619

UTP16
U3 small nucleolar RNA-associated protein 16

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025