Protein: DHI1
11-beta-hydroxysteroid dehydrogenase 1 (11-DH) (11-beta-HSD1) (EC 1.1.1.146) (7-oxosteroid reductase) (EC 1.1.1.201) (Corticosteroid 11-beta-dehydrogenase isozyme 1) (Short chain dehydrogenase/reductase family 26C member 1)

Gene: DHI1, HSD11B1
Organism: Homo sapiens
Interactions: 24
UniProt ID: P28845

Gene Ontology (top 5):
GO:0005496 - steroid binding
GO:0005789 - endoplasmic reticulum membrane
GO:0006706 - steroid catabolic process
GO:0016020 - membrane
GO:0030324 - lung development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

705868

TMX4
Thioredoxin-related transmembrane protein 4

3

5

High-throughput

0.667

High

705861

CGT
2-hydroxyacylsphingosine 1-beta-galactosyltransferase

3

0

High-throughput

0.638

High

705855

DHI1
11-beta-hydroxysteroid dehydrogenase 1

1

16

Small-scale

0.618

High

160690

TOR1A
Torsin-1A

2

2

High-throughput

0.611

High

705857

DAD1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1

2

1

High-throughput

0.611

High

705856

BI1
Bax inhibitor 1

2

0

High-throughput

0.585

High

249430

ACSL4
Long-chain-fatty-acid--CoA ligase 4

1

1

High-throughput

0.536

High

439653

INSR
Insulin receptor

1

11

High-throughput

0.536

High

705858

OS9
Protein OS-9

1

0

High-throughput

0.513

High

705860

NPTX1
Neuronal pentraxin-1

1

1

High-throughput

0.489

High

598581

CD36
Platelet glycoprotein 4

1

0

Small-scale

0.480

High

362820

EGFR
Epidermal growth factor receptor

1

9

High-throughput

0.479

High

705869

RAB18
Ras-related protein Rab-18

1

4

High-throughput

0.479

High

705871

TMX2
Thioredoxin-related transmembrane protein 2

1

3

High-throughput

0.479

High

705864

DIK1A
Divergent protein kinase domain 1A

1

0

High-throughput

0.458

High

342115

BRD1
Bromodomain-containing protein 1

1

2

High-throughput

0.437

High

705862

NHLC3
NHL repeat-containing protein 3

1

1

High-throughput

0.437

High

705866

A16L1
Autophagy-related protein 16-1

1

5

High-throughput

0.407

High

705865

GKAP1
G kinase-anchoring protein 1

1

0

High-throughput

0.282

High

705859

SURF1
Surfeit locus protein 1

1

0

High-throughput

0.279

Low

705863

MANEA
Glycoprotein endo-alpha-1,2-mannosidase

1

0

High-throughput

0.249

Low

705867

GLBL2
Beta-galactosidase-1-like protein 2

1

0

High-throughput

0.249

Low

705870

C42S2
CDC42 small effector protein 2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025