Protein: MANEA
Glycoprotein endo-alpha-1,2-mannosidase (Endo-alpha mannosidase) (Endomannosidase) (hEndo) (EC 3.2.1.130) (Mandaselin)

Gene: MANEA
Organism: Homo sapiens
Interactions: 64
UniProt ID: Q5SRI9

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0004559 - alpha-mannosidase activity
GO:0004569 - glycoprotein endo-alpha-1,2-mannosidase activity
GO:0005794 - Golgi apparatus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1210399

CGAT2
Chondroitin sulfate N-acetylgalactosaminyltransferase 2

2

1

High-throughput

0.628

High

1197785

S39AC
Zinc transporter ZIP12

3

8

High-throughput

0.604

High

533683

CLUS
Clusterin

2

0

High-throughput

0.602

High

1164215

AOC3
Amine oxidase [copper-containing] 3

2

0

High-throughput

0.602

High

1210418

GGT7
Glutathione hydrolase 7

2

1

High-throughput

0.574

High

851130

ACHA4
Neuronal acetylcholine receptor subunit alpha-4

2

1

High-throughput

0.549

High

144053

MA2B1
Lysosomal alpha-mannosidase

1

1

High-throughput

0.536

High

296358

ATRN
Attractin

1

4

High-throughput

0.536

High

1210421

MA2B2
Epididymis-specific alpha-mannosidase

1

1

High-throughput

0.536

High

1210395

S39A4
Zinc transporter ZIP4

2

8

High-throughput

0.521

High

1187197

CC50B
Cell cycle control protein 50B

1

0

High-throughput

0.513

High

1210394

SCAR3
Scavenger receptor class A member 3

1

0

High-throughput

0.513

High

1210413

GLP3L
Golgi phosphoprotein 3-like

1

0

High-throughput

0.513

High

183262

LAMA5
Laminin subunit alpha-5

1

5

High-throughput

0.489

High

270150

LRP3
Low-density lipoprotein receptor-related protein 3

1

1

High-throughput

0.489

High

462884

LAMB1
Laminin subunit beta-1

1

5

High-throughput

0.489

High

470304

NEP
Neprilysin

1

1

High-throughput

0.489

High

535849

LAMC1
Laminin subunit gamma-1

1

4

High-throughput

0.489

High

673773

LAMA1
Laminin subunit alpha-1

1

5

High-throughput

0.489

High

683623

ITB7
Integrin beta-7

1

1

High-throughput

0.489

High

932340

ARSF
Arylsulfatase F

1

1

High-throughput

0.489

High

937402

LAMB2
Laminin subunit beta-2

1

5

High-throughput

0.489

High

1157272

LAMA4
Laminin subunit alpha-4

1

6

High-throughput

0.489

High

1210397

S22A9
Organic anion transporter 7

1

1

High-throughput

0.489

High

1210407

CREL1
Protein disulfide isomerase CRELD1

1

1

High-throughput

0.489

High

1210410

TTYH1
Protein tweety homolog 1

1

1

High-throughput

0.489

High

896783

DYN2
Dynamin-2

1

0

Small-scale

0.480

High

218283

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.479

High

1210396

PLD3
5'-3' exonuclease PLD3

1

0

High-throughput

0.458

High

1210398

S39AB
Zinc transporter ZIP11

1

8

High-throughput

0.445

High

1210402

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

4

High-throughput

0.445

High

1210423

ZNT1
Proton-coupled zinc antiporter SLC30A1

1

4

High-throughput

0.445

High

455976

ASGR2
Asialoglycoprotein receptor 2

1

1

High-throughput

0.437

High

543426

PSG1
Pregnancy-specific beta-1-glycoprotein 1

1

2

High-throughput

0.437

High

1210415

SIAE
Sialate O-acetylesterase

1

1

High-throughput

0.437

High

1210420

S35A3
UDP-N-acetylglucosamine transporter

1

0

High-throughput

0.426

High

539708

ACHB
Acetylcholine receptor subunit beta

1

2

High-throughput

0.407

High

1210405

SAAL1
Protein SAAL1

1

1

High-throughput

0.407

High

1210408

CNDP1
Beta-Ala-His dipeptidase

3

0

High-throughput

0.347

High

1210409

NOE1
Noelin

3

0

High-throughput

0.347

High

1093517

TRDN
Triadin

3

0

High-throughput

0.345

High

1210417

SCN3B
Sodium channel regulatory subunit beta-3

3

0

High-throughput

0.345

High

821725

CD79B
B-cell antigen receptor complex-associated protein beta chain

2

0

High-throughput

0.328

High

1210419

TRHDE
Thyrotropin-releasing hormone-degrading ectoenzyme

2

0

High-throughput

0.328

High

1042631

UPAR
Urokinase plasminogen activator surface receptor

2

0

High-throughput

0.318

High

1210414

ANTR1
Anthrax toxin receptor 1

2

0

High-throughput

0.318

High

1210416

UD110
UDP-glucuronosyltransferase 1A10

2

0

High-throughput

0.318

High

1210406

BSCL2
Seipin

2

0

High-throughput

0.313

High

136910

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

0

High-throughput

0.279

Low

249360

PLXC1
Plexin-C1

1

0

High-throughput

0.279

Low

463983

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

0

High-throughput

0.279

Low

876693

HSP13
Heat shock 70 kDa protein 13

1

0

High-throughput

0.279

Low

1051669

NMDZ1
Glutamate receptor ionotropic, NMDA 1

1

0

High-throughput

0.279

Low

1120534

NID2
Nidogen-2

1

0

High-throughput

0.279

Low

1210400

SIDT2
SID1 transmembrane family member 2

1

0

High-throughput

0.279

Low

1210401

PCYXL
Prenylcysteine oxidase 1-like

1

0

High-throughput

0.279

Low

1210403

TS1R2
Taste receptor type 1 member 2

1

0

High-throughput

0.279

Low

1210412

G3ST2
Galactose-3-O-sulfotransferase 2

1

0

High-throughput

0.279

Low

138152

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

0

High-throughput

0.249

Low

705863

DHI1
11-beta-hydroxysteroid dehydrogenase 1

1

0

High-throughput

0.249

Low

883052

AMPH
Amphiphysin

1

0

Small-scale

0.249

Low

1210411

CPVL
Probable serine carboxypeptidase CPVL

1

0

High-throughput

0.249

Low

1210404

GDPD5
Glycerophosphodiester phosphodiesterase domain-containing protein 5

1

0

High-throughput

0.232

Low

1210422

FLVC1
Choline/ethanolamine transporter FLVCR1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025