Protein: MED11
Mediator of RNA polymerase II transcription subunit 11 (Mediator complex subunit 11)

Gene: MED11
Organism: Homo sapiens
Interactions: 67
UniProt ID: Q9P086

Gene Ontology (top 5):
GO:0000151 - ubiquitin ligase complex
GO:0003712 - transcription coregulator activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0016567 - protein ubiquitination

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1074734

MED22
Mediator of RNA polymerase II transcription subunit 22

4

2

Small-scale

0.911

High

1312770

MED18
Mediator of RNA polymerase II transcription subunit 18

4

1

High-throughput

0.909

High

1328956

MED28
Mediator of RNA polymerase II transcription subunit 28

6

0

Small-scale

0.894

High

1346440

MED17
Mediator of RNA polymerase II transcription subunit 17

3

1

High-throughput

0.871

High

1291852

MED8
Mediator of RNA polymerase II transcription subunit 8

3

2

High-throughput

0.855

High

1293708

MED30
Mediator of RNA polymerase II transcription subunit 30

2

2

High-throughput

0.811

High

1312304

MED10
Mediator of RNA polymerase II transcription subunit 10

8

1

Small-scale

0.754

High

1347848

MED29
Mediator of RNA polymerase II transcription subunit 29

7

1

Small-scale

0.750

High

826367

CDK8
Cyclin-dependent kinase 8

6

2

High-throughput

0.734

High

48737

MED19
Mediator of RNA polymerase II transcription subunit 19

9

0

Small-scale

0.724

High

206658

MED7
Mediator of RNA polymerase II transcription subunit 7

5

1

High-throughput

0.722

High

1274356

MED12
Mediator of RNA polymerase II transcription subunit 12

5

1

High-throughput

0.718

High

1342929

MED4
Mediator of RNA polymerase II transcription subunit 4

4

1

High-throughput

0.702

High

1314887

CDK19
Cyclin-dependent kinase 19

4

2

High-throughput

0.699

High

1334006

MED20
Mediator of RNA polymerase II transcription subunit 20

4

1

High-throughput

0.699

High

624523

CCNC
Cyclin-C

4

1

High-throughput

0.694

High

1076208

MED1
Mediator of RNA polymerase II transcription subunit 1

5

0

Small-scale

0.688

High

1037108

MED21
Mediator of RNA polymerase II transcription subunit 21

4

0

High-throughput

0.674

High

313472

MED26
Mediator of RNA polymerase II transcription subunit 26

4

0

High-throughput

0.670

High

1347147

MED9
Mediator of RNA polymerase II transcription subunit 9

4

0

Small-scale

0.670

High

1349549

MED13
Mediator of RNA polymerase II transcription subunit 13

3

2

High-throughput

0.662

High

265371

MED24
Mediator of RNA polymerase II transcription subunit 24

3

0

High-throughput

0.638

High

1349550

MED23
Mediator of RNA polymerase II transcription subunit 23

2

1

High-throughput

0.628

High

1349552

MED31
Mediator of RNA polymerase II transcription subunit 31

2

1

High-throughput

0.628

High

225428

MED14
Mediator of RNA polymerase II transcription subunit 14

2

2

High-throughput

0.611

High

270538

MED6
Mediator of RNA polymerase II transcription subunit 6

2

1

High-throughput

0.611

High

1158930

MED27
Mediator of RNA polymerase II transcription subunit 27

2

1

High-throughput

0.611

High

1174783

MD13L
Mediator of RNA polymerase II transcription subunit 13-like

2

2

High-throughput

0.611

High

1206165

MD12L
Mediator of RNA polymerase II transcription subunit 12-like protein

2

1

High-throughput

0.611

High

1301097

MED15
Mediator of RNA polymerase II transcription subunit 15

2

1

High-throughput

0.611

High

1349551

MED16
Mediator of RNA polymerase II transcription subunit 16

2

1

High-throughput

0.611

High

583610

RPB3
DNA-directed RNA polymerase II subunit RPB3

2

0

High-throughput

0.585

High

583828

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

2

0

High-throughput

0.585

High

625075

RPB1
DNA-directed RNA polymerase II subunit RPB1

2

0

High-throughput

0.585

High

677038

RPB2
DNA-directed RNA polymerase II subunit RPB2

2

0

High-throughput

0.585

High

245037

BRD4
Bromodomain-containing protein 4

2

1

High-throughput

0.584

High

1161775

SYCE2
Synaptonemal complex central element protein 2

2

0

High-throughput

0.580

High

1290305

SGF29
SAGA-associated factor 29

2

0

High-throughput

0.580

High

1348415

ABI2
Abl interactor 2

2

0

High-throughput

0.580

High

1349554

NDK7
Nucleoside diphosphate kinase homolog 7

2

0

High-throughput

0.580

High

1281438

FBXW7
F-box/WD repeat-containing protein 7

2

0

Small-scale

0.559

High

529824

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.518

High

181475

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

0

High-throughput

0.513

High

959982

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.513

High

989406

PRDX1
Peroxiredoxin-1

1

0

High-throughput

0.513

High

1157391

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

1

0

High-throughput

0.513

High

1160904

FXL19
F-box/LRR-repeat protein 19

1

0

High-throughput

0.513

High

1174973

MED25
Mediator of RNA polymerase II transcription subunit 25

1

0

High-throughput

0.513

High

1349553

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

0

High-throughput

0.513

High

1067169

BRD3
Bromodomain-containing protein 3

1

1

High-throughput

0.479

High

1306549

EPAS1
Endothelial PAS domain-containing protein 1

1

1

Small-scale

0.479

High

738902

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

0

High-throughput

0.458

High

854385

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

0

High-throughput

0.458

High

913972

RPB7
DNA-directed RNA polymerase II subunit RPB7

1

0

High-throughput

0.458

High

1076299

TRIP4
Activating signal cointegrator 1

1

0

High-throughput

0.458

High

1173778

ACD11
Acyl-CoA dehydrogenase family member 11

1

0

High-throughput

0.458

High

91316

E5RFK5
Cyclin-C

1

1

High-throughput

0.445

High

1297420

CI072
Guanine nucleotide exchange factor C9orf72

1

0

Small-scale

0.426

High

1301404

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.426

High

50873

SRCRL
Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D

2

0

High-throughput

0.316

High

616663

GCSH
Glycine cleavage system H protein, mitochondrial

2

0

High-throughput

0.316

High

1236727

USBP1
Harmonin-binding protein USHBP1

2

0

High-throughput

0.316

High

1293367

CC120
Coiled-coil domain-containing protein 120

2

0

High-throughput

0.316

High

1326019

NDEL1
Nuclear distribution protein nudE-like 1

2

0

High-throughput

0.316

High

1230190

CNTRB
Centrobin

1

0

High-throughput

0.279

Low

395945

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.261

Low

361619

APOA2
Apolipoprotein A-II

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024