Protein: TET1
Methylcytosine dioxygenase TET1 (EC 1.14.11.80) (CXXC-type zinc finger protein 6) (Leukemia-associated protein with a CXXC domain) (Ten-eleven translocation 1 gene protein)

Gene: TET1
Organism: Homo sapiens
Interactions: 29
UniProt ID: Q8NFU7

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001826 - inner cell mass cell differentiation
GO:0003677 - DNA binding
GO:0005506 - iron ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

175056

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

3

5

Small-scale

0.650

High

1085611

HIF1A
Hypoxia-inducible factor 1-alpha

2

1

Small-scale

0.584

High

1245000

DCAF1
DDB1- and CUL4-associated factor 1

2

4

Small-scale

0.584

High

909832

1433E
14-3-3 protein epsilon

1

1

High-throughput

0.536

High

1087277

H2B2E
Histone H2B type 2-E

1

1

High-throughput

0.536

High

1244992

PSPC1
Paraspeckle component 1

1

5

High-throughput

0.536

High

639022

S100P
Protein S100-P

1

0

High-throughput

0.513

High

328607

MBD3
Methyl-CpG-binding domain protein 3

1

2

Small-scale

0.501

High

647124

1433T
14-3-3 protein theta

1

10

High-throughput

0.489

High

904887

1433G
14-3-3 protein gamma

1

10

High-throughput

0.489

High

982300

1433F
14-3-3 protein eta

1

10

High-throughput

0.489

High

232343

KDM1A
Lysine-specific histone demethylase 1A

1

4

High-throughput

0.479

High

382079

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

1

High-throughput

0.479

High

505261

EGR2
E3 SUMO-protein ligase EGR2

1

3

High-throughput

0.479

High

1038548

HDAC1
Histone deacetylase 1

1

4

High-throughput

0.479

High

1043110

CUL4A
Cullin-4A

1

3

Small-scale

0.479

High

1043463

CUL4B
Cullin-4B

1

3

Small-scale

0.479

High

1082291

DDB1
DNA damage-binding protein 1

1

2

Small-scale

0.479

High

1188583

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.479

High

1244996

UHRF1
E3 ubiquitin-protein ligase UHRF1

1

1

Small-scale

0.479

High

1244997

EPAS1
Endothelial PAS domain-containing protein 1

1

1

Small-scale

0.479

High

1244999

RCOR1
REST corepressor 1

1

1

High-throughput

0.479

High

808782

YAP1
Transcriptional coactivator YAP1

1

0

High-throughput

0.458

High

815274

TISD
mRNA decay activator protein ZFP36L2

1

0

High-throughput

0.458

High

1244993

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

0

High-throughput

0.458

High

1244994

PF21A
PHD finger protein 21A

1

0

High-throughput

0.458

High

1244998

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.458

High

1244995

SIN3A
Paired amphipathic helix protein Sin3a

1

3

Small-scale

0.445

High

995063

GOGA2
Golgin subfamily A member 2

1

2

High-throughput

0.437

High


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Last updated: 15 Jul 2024