Protein: BBS1
BBSome complex member BBS1 (BBS2-like protein 2) (Bardet-Biedl syndrome 1 protein)

Gene: BBS1
Organism: Homo sapiens
Interactions: 136
UniProt ID: Q8NFJ9

Gene Ontology (top 5):
GO:0000226 - microtubule cytoskeleton organization
GO:0001764 - neuron migration
GO:0005113 - patched binding
GO:0005119 - smoothened binding
GO:0005813 - centrosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1339339

ARL6
ADP-ribosylation factor-like protein 6

4

0

Small-scale

0.846

High

1187954

PTHB1
Protein PTHB1

8

1

Small-scale

0.750

High

1339325

BBS4
BBSome complex member BBS4

7

3

Small-scale

0.744

High

1311497

BBS7
BBSome complex member BBS7

6

1

Small-scale

0.735

High

1339336

BBS2
BBSome complex member BBS2

5

1

Small-scale

0.718

High

1339308

TTC8
Tetratricopeptide repeat protein 8

5

3

Small-scale

0.714

High

1325179

BBS5
BBSome complex member BBS5

6

0

Small-scale

0.701

High

1339343

LZTL1
Leucine zipper transcription factor-like protein 1

4

0

High-throughput

0.664

High

1339326

PARK7
Parkinson disease protein 7

3

0

Small-scale

0.633

High

277461

AVIL
Advillin

2

0

High-throughput

0.602

High

1339317

KBP
KIF-binding protein

2

0

High-throughput

0.602

High

1339318

IFT43
Intraflagellar transport protein 43 homolog

2

0

High-throughput

0.602

High

1339347

DPP3
Dipeptidyl peptidase 3

2

0

High-throughput

0.602

High

1123725

DCTN1
Dynactin subunit 1

2

0

Small-scale

0.593

High

1339324

RAB3I
Rab-3A-interacting protein

2

0

Small-scale

0.576

High

208540

PJA2
E3 ubiquitin-protein ligase Praja-2

1

1

Small-scale

0.561

High

421196

ALDOB
Fructose-bisphosphate aldolase B

1

0

Small-scale

0.549

High

171282

MYPT1
Protein phosphatase 1 regulatory subunit 12A

1

1

High-throughput

0.536

High

239325

MYPT2
Protein phosphatase 1 regulatory subunit 12B

1

1

High-throughput

0.536

High

270832

ROCK2
Rho-associated protein kinase 2

1

2

High-throughput

0.536

High

1106284

ROCK1
Rho-associated protein kinase 1

1

2

High-throughput

0.536

High

1153725

TOM34
Mitochondrial import receptor subunit TOM34

1

4

High-throughput

0.536

High

1331341

ENAH
Protein enabled homolog

1

1

High-throughput

0.536

High

1339334

RN126
E3 ubiquitin-protein ligase RNF126

1

1

High-throughput

0.536

High

1339341

SLK
STE20-like serine/threonine-protein kinase

1

4

High-throughput

0.536

High

1339350

STK26
Serine/threonine-protein kinase 26

1

1

High-throughput

0.536

High

1339360

STK24
Serine/threonine-protein kinase 24

1

1

High-throughput

0.536

High

996250

EF1A1
Elongation factor 1-alpha 1

1

0

Small-scale

0.529

High

223470

RGS10
Regulator of G-protein signaling 10

1

0

High-throughput

0.513

High

295354

EIF3J
Eukaryotic translation initiation factor 3 subunit J

1

0

High-throughput

0.513

High

337374

PARN
Poly(A)-specific ribonuclease PARN

1

0

High-throughput

0.513

High

391363

FRIL
Ferritin light chain

1

0

High-throughput

0.513

High

479445

SRP19
Signal recognition particle 19 kDa protein

1

0

High-throughput

0.513

High

537549

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.513

High

549644

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

0

High-throughput

0.513

High

663371

KTHY
Thymidylate kinase

1

0

High-throughput

0.513

High

955973

RAB8A
Ras-related protein Rab-8A

1

0

High-throughput

0.513

High

961616

PHS
Pterin-4-alpha-carbinolamine dehydratase

1

0

High-throughput

0.513

High

1050483

UBE3A
Ubiquitin-protein ligase E3A

1

0

High-throughput

0.513

High

1054616

PSME1
Proteasome activator complex subunit 1

1

0

High-throughput

0.513

High

1098730

NDK3
Nucleoside diphosphate kinase 3

1

0

High-throughput

0.513

High

1104920

XRCC4
DNA repair protein XRCC4

1

0

High-throughput

0.513

High

1106006

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

0

High-throughput

0.513

High

1107576

PICAL
Phosphatidylinositol-binding clathrin assembly protein

1

0

High-throughput

0.513

High

1135665

NAA25
N-alpha-acetyltransferase 25, NatB auxiliary subunit

1

0

High-throughput

0.513

High

1144084

TEBP
Prostaglandin E synthase 3

1

0

High-throughput

0.513

High

1150879

CIP4
Cdc42-interacting protein 4

1

0

High-throughput

0.513

High

1324902

RHG18
Rho GTPase-activating protein 18

1

0

High-throughput

0.513

High

1329342

ARFG2
ADP-ribosylation factor GTPase-activating protein 2

1

0

High-throughput

0.513

High

1339313

FBXW5
F-box/WD repeat-containing protein 5

1

0

High-throughput

0.513

High

1339314

CLUA1
Clusterin-associated protein 1

1

0

High-throughput

0.513

High

1339322

CCD43
Coiled-coil domain-containing protein 43

1

0

High-throughput

0.513

High

1339328

CIB1
Calcium and integrin-binding protein 1

1

0

High-throughput

0.513

High

1339330

VRK1
Serine/threonine-protein kinase VRK1

1

0

High-throughput

0.513

High

1339332

PDC10
Programmed cell death protein 10

1

0

High-throughput

0.513

High

1339342

CHM1A
Charged multivesicular body protein 1a

1

0

High-throughput

0.513

High

1339355

CAB39
Calcium-binding protein 39

1

0

High-throughput

0.513

High

1339356

SBDS
Ribosome maturation protein SBDS

1

0

High-throughput

0.513

High

436947

K1C18
Keratin, type I cytoskeletal 18

1

0

Small-scale

0.486

High

1040065

PAX2
Paired box protein Pax-2

1

0

Small-scale

0.486

High

1121827

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

0

Small-scale

0.486

High

1310246

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

Small-scale

0.486

High

1339312

BHMT1
Betaine--homocysteine S-methyltransferase 1

1

0

Small-scale

0.486

High

1339327

EPAS1
Endothelial PAS domain-containing protein 1

1

0

Small-scale

0.486

High

1339353

EXOC7
Exocyst complex component 7

1

0

Small-scale

0.486

High

1339358

FHOD1
FH1/FH2 domain-containing protein 1

1

0

Small-scale

0.486

High

1140114

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

0

Small-scale

0.479

High

1308558

NUDC3
NudC domain-containing protein 3

1

1

High-throughput

0.479

High

1339354

NUDC
Nuclear migration protein nudC

1

1

High-throughput

0.479

High

223193

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

571478

GLU2B
Glucosidase 2 subunit beta

1

0

High-throughput

0.458

High

1121467

KEAP1
Kelch-like ECH-associated protein 1

1

0

High-throughput

0.458

High

1146437

KS6A2
Ribosomal protein S6 kinase alpha-2

1

0

High-throughput

0.458

High

1193707

C2CD3
C2 domain-containing protein 3

1

0

Small-scale

0.458

High

1257190

BBS12
Chaperonin-containing T-complex member BBS12

1

0

Small-scale

0.458

High

1339333

CC28B
Coiled-coil domain-containing protein 28B

1

0

Small-scale

0.458

High

1339335

OSB10
Oxysterol-binding protein-related protein 10

1

0

High-throughput

0.458

High

884467

PCY1A
Choline-phosphate cytidylyltransferase A

1

1

High-throughput

0.445

High

898122

LRBA
Lipopolysaccharide-responsive and beige-like anchor protein

1

1

High-throughput

0.445

High

1204769

PP6R3
Serine/threonine-protein phosphatase 6 regulatory subunit 3

1

1

High-throughput

0.445

High

1339307

NBEA
Neurobeachin

1

1

High-throughput

0.445

High

1339340

GAN
Gigaxonin

1

1

High-throughput

0.445

High

1339352

PP6R1
Serine/threonine-protein phosphatase 6 regulatory subunit 1

1

1

High-throughput

0.445

High

299299

FLOT1
Flotillin-1

1

0

Small-scale

0.438

High

952963

ACTB
Actin, cytoplasmic 1

1

0

Small-scale

0.438

High

1143431

PCM1
Pericentriolar material 1 protein

1

0

Small-scale

0.438

High

1339310

SNX29
Sorting nexin-29

1

1

High-throughput

0.437

High

71032

BBIP1
BBSome-interacting protein 1

1

0

Small-scale

0.426

High

884839

PPM1F
Protein phosphatase 1F

1

0

High-throughput

0.426

High

898505

PPT1
Palmitoyl-protein thioesterase 1

1

0

High-throughput

0.426

High

1244621

GASP3
G protein-coupled receptor associated sorting protein 3

1

0

High-throughput

0.426

High

1063817

LG3BP
Galectin-3-binding protein

1

1

High-throughput

0.407

High

1339357

PCY1B
Choline-phosphate cytidylyltransferase B

1

1

High-throughput

0.407

High

1339316

TRI44
Tripartite motif-containing protein 44

2

0

High-throughput

0.328

High

1339329

OMD
Osteomodulin

2

0

High-throughput

0.328

High

1339344

SYIM
Isoleucine--tRNA ligase, mitochondrial

2

0

High-throughput

0.328

High

1279435

WDR53
WD repeat-containing protein 53

2

0

High-throughput

0.318

High

49332

SHOT1
Shootin-1

1

0

High-throughput

0.279

Low

61753

SBNO1
Protein strawberry notch homolog 1

1

0

High-throughput

0.279

Low

139404

VMA5A
von Willebrand factor A domain-containing protein 5A

1

0

High-throughput

0.279

Low

225208

GATC
Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial

1

0

High-throughput

0.279

Low

226986

ENSA
Alpha-endosulfine

1

0

High-throughput

0.279

Low

286484

WBP4
WW domain-binding protein 4

1

0

High-throughput

0.279

Low

617452

DNLI1
DNA ligase 1

1

0

High-throughput

0.279

Low

851960

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.279

Low

885593

PRI2
DNA primase large subunit

1

0

High-throughput

0.279

Low

1131202

MESD
LRP chaperone MESD

1

0

High-throughput

0.279

Low

1147968

SF3B3
Splicing factor 3B subunit 3

1

0

High-throughput

0.279

Low

1157152

PDCD2
Programmed cell death protein 2

1

0

High-throughput

0.279

Low

1207236

SOLH1
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1

1

0

High-throughput

0.279

Low

1229497

C19L1
CWF19-like protein 1

1

0

High-throughput

0.279

Low

1244562

SYDM
Aspartate--tRNA ligase, mitochondrial

1

0

High-throughput

0.279

Low

1339309

HAVR2
Hepatitis A virus cellular receptor 2

1

0

High-throughput

0.279

Low

1339311

UBCP1
Ubiquitin-like domain-containing CTD phosphatase 1

1

0

High-throughput

0.279

Low

1339315

ARK2N
Protein ARK2N

1

0

High-throughput

0.279

Low

1339319

BT3L4
Transcription factor BTF3 homolog 4

1

0

High-throughput

0.279

Low

1339320

TOPK
Lymphokine-activated killer T-cell-originated protein kinase

1

0

High-throughput

0.279

Low

1339321

PPM1M
Protein phosphatase 1M

1

0

High-throughput

0.279

Low

1339323

PUS7
Pseudouridylate synthase 7 homolog

1

0

High-throughput

0.279

Low

1339331

CMS1
Protein CMSS1

1

0

High-throughput

0.279

Low

1339337

RTF2
Replication termination factor 2

1

0

High-throughput

0.279

Low

1339345

PDRG1
p53 and DNA damage-regulated protein 1

1

0

High-throughput

0.279

Low

1339346

CYRIB
CYFIP-related Rac1 interactor B

1

0

High-throughput

0.279

Low

1339348

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.279

Low

1339351

MCTS1
Malignant T-cell-amplified sequence 1

1

0

High-throughput

0.279

Low

1339359

EMIL1
EMILIN-1

1

0

High-throughput

0.279

Low

449655

CALCA
Calcitonin gene-related peptide 1

1

0

Small-scale

0.265

Low

835579

TSN7
Tetraspanin-7

1

0

Small-scale

0.251

Low

1200049

EIPR1
EARP and GARP complex-interacting protein 1

1

0

High-throughput

0.249

Low

1251990

LDH6A
L-lactate dehydrogenase A-like 6A

1

0

High-throughput

0.249

Low

1339338

GLIS2
Zinc finger protein GLIS2

1

0

Small-scale

0.249

Low

95932

E7ESJ3
Ankyrin repeat domain containing 26

1

0

High-throughput

0.238

Low

1200246

T4S20
Transmembrane 4 L6 family member 20

1

0

Small-scale

0.238

Low

239141

ZNRD2
Protein ZNRD2

1

0

High-throughput

0.232

Low

1248228

CSPG4
Chondroitin sulfate proteoglycan 4

1

0

High-throughput

0.232

Low

1339349

PP4RL
Putative serine/threonine-protein phosphatase 4 regulatory subunit 1-like

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025