Protein: CEP89
Centrosomal protein of 89 kDa (Cep89) (Centrosomal protein 123) (Cep123) (Coiled-coil domain-containing protein 123)

Gene: CEP89
Organism: Homo sapiens
Interactions: 146
UniProt ID: Q96ST8

Gene Ontology (top 5):
GO:0000922 - spindle pole
GO:0005758 - mitochondrial intermembrane space
GO:0005813 - centrosome
GO:0005814 - centriole
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1403080

PICK1
PRKCA-binding protein

5

0

High-throughput

0.687

High

966781

1433G
14-3-3 protein gamma

4

20

High-throughput

0.683

High

1049697

1433F
14-3-3 protein eta

4

20

High-throughput

0.683

High

968652

NCS1
Neuronal calcium sensor 1

4

0

High-throughput

0.665

High

691360

1433T
14-3-3 protein theta

3

20

High-throughput

0.650

High

730177

1433B
14-3-3 protein beta/alpha

3

20

High-throughput

0.650

High

971913

1433E
14-3-3 protein epsilon

3

3

High-throughput

0.633

High

1240766

PMF1
Polyamine-modulated factor 1

2

0

High-throughput

0.585

High

1403076

CEP15
Centrosomal protein 15

2

0

High-throughput

0.585

High

978242

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.584

High

1143491

PCM1
Pericentriolar material 1 protein

2

2

High-throughput

0.584

High

900110

FXR1
RNA-binding protein FXR1

1

7

High-throughput

0.541

High

772972

MYH9
Myosin-9

1

18

High-throughput

0.536

High

839915

AF9
Protein AF-9

1

12

High-throughput

0.536

High

1040750

ENL
Protein ENL

1

13

High-throughput

0.536

High

1095764

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

18

High-throughput

0.536

High

1353784

HASP
Serine/threonine-protein kinase haspin

1

2

High-throughput

0.536

High

1357199

BRK1
Protein BRICK1

1

1

High-throughput

0.536

High

1403085

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

3

High-throughput

0.536

High

1219880

OBI1
ORC ubiquitin ligase 1

2

1

High-throughput

0.533

High

911863

GDS1
Rap1 GTPase-GDP dissociation stimulator 1

1

0

High-throughput

0.513

High

171920

ZN263
Zinc finger protein 263

1

4

High-throughput

0.489

High

848706

MAGA9
Melanoma-associated antigen 9

1

10

High-throughput

0.489

High

1244545

KCD18
BTB/POZ domain-containing protein KCTD18

1

14

High-throughput

0.489

High

1380705

TOP1M
DNA topoisomerase I, mitochondrial

1

3

High-throughput

0.489

High

126759

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

159257

ABLM1
Actin-binding LIM protein 1

1

7

High-throughput

0.479

High

164063

NDC80
Kinetochore protein NDC80 homolog

1

18

High-throughput

0.479

High

273362

NPHP4
Nephrocystin-4

1

3

High-throughput

0.479

High

290121

OFD1
Centriole and centriolar satellite protein OFD1

1

1

High-throughput

0.479

High

323546

TRI37
E3 ubiquitin-protein ligase TRIM37

1

20

High-throughput

0.479

High

375862

RASK
GTPase KRas

1

20

High-throughput

0.479

High

402995

ANXA1
Annexin A1

1

9

High-throughput

0.479

High

437314

K2C8
Keratin, type II cytoskeletal 8

1

5

High-throughput

0.479

High

440181

LCK
Tyrosine-protein kinase Lck

1

16

High-throughput

0.479

High

461846

HS90A
Heat shock protein HSP 90-alpha

1

12

High-throughput

0.479

High

463719

LYN
Tyrosine-protein kinase Lyn

1

16

High-throughput

0.479

High

466428

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.479

High

468718

HS90B
Heat shock protein HSP 90-beta

1

12

High-throughput

0.479

High

605789

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

14

High-throughput

0.479

High

720795

PUR8
Adenylosuccinate lyase

1

1

High-throughput

0.479

High

730847

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

821189

TXLNA
Alpha-taxilin

1

19

High-throughput

0.479

High

855734

CRK
Adapter molecule crk

1

10

High-throughput

0.479

High

936423

AFAD
Afadin

1

20

High-throughput

0.479

High

953630

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

962410

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

988635

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

990637

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.479

High

1004173

CXAR
Coxsackievirus and adenovirus receptor

1

9

High-throughput

0.479

High

1015701

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.479

High

1093296

FLII
Protein flightless-1 homolog

1

15

High-throughput

0.479

High

1115596

ASPP2
Apoptosis-stimulating of p53 protein 2

1

12

High-throughput

0.479

High

1140730

KIF14
Kinesin-like protein KIF14

1

15

High-throughput

0.479

High

1145072

RAB35
Ras-related protein Rab-35

1

9

High-throughput

0.479

High

1169029

CSPP1
Centrosome and spindle pole-associated protein 1

1

2

High-throughput

0.479

High

1178623

KIF7
Kinesin-like protein KIF7

1

5

High-throughput

0.479

High

1193468

CCD14
Coiled-coil domain-containing protein 14

1

1

High-throughput

0.479

High

1210962

CE170
Centrosomal protein of 170 kDa

1

19

High-throughput

0.479

High

1215496

CE162
Centrosomal protein of 162 kDa

1

19

High-throughput

0.479

High

1217498

CE350
Centrosome-associated protein 350

1

19

High-throughput

0.479

High

1227316

A16L1
Autophagy-related protein 16-1

1

15

High-throughput

0.479

High

1241111

C2D1A
Coiled-coil and C2 domain-containing protein 1A

1

13

High-throughput

0.479

High

1256567

CE128
Centrosomal protein of 128 kDa

1

19

High-throughput

0.479

High

1258304

MOB2
MOB kinase activator 2

1

5

High-throughput

0.479

High

1278433

HAUS6
HAUS augmin-like complex subunit 6

1

2

High-throughput

0.479

High

1280906

CNTRL
Centriolin

1

19

High-throughput

0.479

High

1289969

LUZP1
Leucine zipper protein 1

1

19

High-throughput

0.479

High

1307189

RB6I2
ELKS/Rab6-interacting/CAST family member 1

1

20

High-throughput

0.479

High

1312368

SIR2
NAD-dependent protein deacetylase sirtuin-2

1

7

High-throughput

0.479

High

1316438

XRN1
5'-3' exoribonuclease 1

1

1

High-throughput

0.479

High

1351383

DLG5
Disks large homolog 5

1

10

High-throughput

0.479

High

1353251

PARD3
Partitioning defective 3 homolog

1

13

High-throughput

0.479

High

1361142

PIBF1
Progesterone-induced-blocking factor 1

1

2

High-throughput

0.479

High

1387724

TBC31
TBC1 domain family member 31

1

17

High-throughput

0.479

High

1403069

TCHP
Trichoplein keratin filament-binding protein

1

18

High-throughput

0.479

High

1403070

K1671
Uncharacterized protein KIAA1671

1

1

High-throughput

0.479

High

1403071

UN45A
Protein unc-45 homolog A

1

17

High-throughput

0.479

High

1403075

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.479

High

1403082

LATS2
Serine/threonine-protein kinase LATS2

1

18

High-throughput

0.479

High

1403083

TXLNG
Gamma-taxilin

1

17

High-throughput

0.479

High

1403087

CEP72
Centrosomal protein of 72 kDa

1

11

High-throughput

0.479

High

1403088

WRP73
WD repeat-containing protein WRAP73

1

16

High-throughput

0.479

High

1403089

PKHG1
Pleckstrin homology domain-containing family G member 1

1

15

High-throughput

0.479

High

1403090

CP131
Centrosomal protein of 131 kDa

1

20

High-throughput

0.479

High

1403091

ANR26
Ankyrin repeat domain-containing protein 26

1

19

High-throughput

0.479

High

1403092

TBD2B
TBC1 domain family member 2B

1

13

High-throughput

0.479

High

1403093

CE164
Centrosomal protein of 164 kDa

1

18

High-throughput

0.479

High

1403095

NINL
Ninein-like protein

1

20

High-throughput

0.479

High

1403097

WIPI4
WD repeat domain phosphoinositide-interacting protein 4

1

20

High-throughput

0.479

High

1403098

NDK7
Nucleoside diphosphate kinase homolog 7

1

2

High-throughput

0.479

High

60804

CCD66
Coiled-coil domain-containing protein 66

1

0

High-throughput

0.458

High

322454

HAUS5
HAUS augmin-like complex subunit 5

1

0

High-throughput

0.458

High

342019

CEP43
Centrosomal protein 43

1

0

High-throughput

0.458

High

719658

NMT1
Glycylpeptide N-tetradecanoyltransferase 1

1

0

High-throughput

0.458

High

1177996

MOONR
Protein moonraker

1

0

High-throughput

0.458

High

1193714

C2CD3
C2 domain-containing protein 3

1

0

High-throughput

0.458

High

1198507

CEP55
Centrosomal protein of 55 kDa

1

0

High-throughput

0.458

High

1208569

SMAG2
Protein Smaug homolog 2

1

0

High-throughput

0.458

High

1228562

HAUS3
HAUS augmin-like complex subunit 3

1

0

High-throughput

0.458

High

1385685

ENTR1
Endosome-associated-trafficking regulator 1

1

0

High-throughput

0.458

High

1403062

MPP9
M-phase phosphoprotein 9

1

0

High-throughput

0.458

High

1403064

HAUS7
HAUS augmin-like complex subunit 7

1

0

High-throughput

0.458

High

1403065

CCD77
Coiled-coil domain-containing protein 77

1

0

High-throughput

0.458

High

1403068

HAUS8
HAUS augmin-like complex subunit 8

1

0

High-throughput

0.458

High

1403074

HAUS4
HAUS augmin-like complex subunit 4

1

0

High-throughput

0.458

High

1403084

HAUS2
HAUS augmin-like complex subunit 2

1

0

High-throughput

0.458

High

1403094

ADIP
Afadin- and alpha-actinin-binding protein

1

0

High-throughput

0.458

High

1403081

DISC1
Disrupted in schizophrenia 1 protein

1

6

High-throughput

0.457

High

1398333

CEP63
Centrosomal protein of 63 kDa

1

18

High-throughput

0.445

High

181726

CTDSL
CTD small phosphatase-like protein

1

4

High-throughput

0.437

High

189788

STX7
Syntaxin-7

1

5

High-throughput

0.437

High

292201

S2512
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

1

6

High-throughput

0.437

High

299344

FLOT1
Flotillin-1

1

8

High-throughput

0.437

High

327418

ZFPL1
Zinc finger protein-like 1

1

1

High-throughput

0.437

High

341128

DIRA3
GTP-binding protein Di-Ras3

1

12

High-throughput

0.437

High

601414

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.437

High

604167

CXA1
Gap junction alpha-1 protein

1

6

High-throughput

0.437

High

659055

PTPRG
Receptor-type tyrosine-protein phosphatase gamma

1

3

High-throughput

0.437

High

710442

EPHA2
Ephrin type-A receptor 2

1

10

High-throughput

0.437

High

755619

TTK
Dual specificity protein kinase TTK

1

10

High-throughput

0.437

High

1159815

OCLN
Occludin

1

2

High-throughput

0.437

High

1270506

MARK2
Serine/threonine-protein kinase MARK2

1

12

High-throughput

0.437

High

1309945

MA7D3
MAP7 domain-containing protein 3

1

8

High-throughput

0.437

High

1314635

M21D2
Nucleotidyltransferase MB21D2

1

1

High-throughput

0.437

High

1327519

SRBD1
S1 RNA-binding domain-containing protein 1

1

3

High-throughput

0.437

High

1338102

NAV1
Neuron navigator 1

1

12

High-throughput

0.437

High

1381941

CK052
Uncharacterized protein C11orf52

1

2

High-throughput

0.437

High

1383655

VP33A
Vacuolar protein sorting-associated protein 33A

1

4

High-throughput

0.437

High

1403066

GPTC1
G patch domain-containing protein 1

1

9

High-throughput

0.437

High

1403067

WDR83
WD repeat domain-containing protein 83

1

17

High-throughput

0.437

High

1403072

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.437

High

1403073

DHX35
Probable ATP-dependent RNA helicase DHX35

1

6

High-throughput

0.437

High

1403078

E41LA
Band 4.1-like protein 4A

1

13

High-throughput

0.437

High

1403079

MED4
Mediator of RNA polymerase II transcription subunit 4

1

1

High-throughput

0.437

High

1403086

GAR1
H/ACA ribonucleoprotein complex subunit 1

1

2

High-throughput

0.437

High

1403096

PHOCN
MOB-like protein phocein

1

5

High-throughput

0.437

High

1167105

WHAL1
Putative WASP homolog-associated protein with actin, membranes and microtubules-like protein 1

1

2

High-throughput

0.407

High

1258555

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

2

High-throughput

0.407

High

1403063

ZBT18
Zinc finger and BTB domain-containing protein 18

1

7

High-throughput

0.407

High

66655

CC85C
Coiled-coil domain-containing protein 85C

1

0

High-throughput

0.249

Low

1385160

ATG2B
Autophagy-related protein 2 homolog B

1

0

High-throughput

0.249

Low

1392329

BORC6
BLOC-1-related complex subunit 6

1

0

High-throughput

0.249

Low

1397827

CC138
Coiled-coil domain-containing protein 138

1

0

High-throughput

0.249

Low

1398225

HS12B
Heat shock 70 kDa protein 12B

1

0

High-throughput

0.249

Low

1403077

Q9HCK3
KIAA1569 protein

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025