Protein: APT
Adenine phosphoribosyltransferase (APRT) (EC 2.4.2.7)

Gene: APT, APRT
Organism: Homo sapiens
Interactions: 82
UniProt ID: P07741

Gene Ontology (top 5):
GO:0002055 - adenine binding
GO:0003999 - adenine phosphoribosyltransferase activity
GO:0005576 - extracellular region
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

430504

NEMO
NF-kappa-B essential modulator

1

1

High-throughput

0.561

High

226287

PRKN
E3 ubiquitin-protein ligase parkin

2

0

High-throughput

0.559

High

373540

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

0

High-throughput

0.559

High

430444

VCAM1
Vascular cell adhesion protein 1

2

0

High-throughput

0.547

High

430468

KPCD1
Serine/threonine-protein kinase D1

2

0

High-throughput

0.547

High

430470

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

0

High-throughput

0.547

High

430482

MK15
Mitogen-activated protein kinase 15

1

1

High-throughput

0.536

High

430479

UN45B
Protein unc-45 homolog B

1

1

High-throughput

0.515

High

336314

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.513

High

430451

PSB10
Proteasome subunit beta type-10

1

0

High-throughput

0.513

High

430478

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

430494

ANKZ1
tRNA endonuclease ANKZF1

1

0

High-throughput

0.513

High

430452

VHL
von Hippel-Lindau disease tumor suppressor

1

0

High-throughput

0.493

High

430473

KLH24
Kelch-like protein 24

1

0

High-throughput

0.493

High

430476

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.493

High

430453

MLH1
DNA mismatch repair protein Mlh1

1

0

Small-scale

0.486

High

393944

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

430458

SUMO2
Small ubiquitin-related modifier 2

1

0

High-throughput

0.480

High

177791

TMPS2
Transmembrane protease serine 2

1

1

High-throughput

0.479

High

430437

ANDR
Androgen receptor

1

1

High-throughput

0.479

High

430449

DUS1
Dual specificity protein phosphatase 1

1

2

High-throughput

0.479

High

430462

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

1

1

High-throughput

0.479

High

430474

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

430485

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

430492

DUS21
Dual specificity protein phosphatase 21

1

2

High-throughput

0.479

High

430496

DUS22
Dual specificity protein phosphatase 22

1

3

High-throughput

0.479

High

430500

DUS12
Dual specificity protein phosphatase 12

1

3

High-throughput

0.479

High

329253

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.458

High

337785

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.458

High

351699

SOMA
Somatotropin

1

0

High-throughput

0.458

High

359576

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.458

High

362701

FINC
Fibronectin

1

0

High-throughput

0.458

High

427969

TBB5
Tubulin beta chain

1

0

High-throughput

0.458

High

430439

ITA4
Integrin alpha-4

1

0

High-throughput

0.458

High

430440

PLAK
Junction plakoglobin

1

0

High-throughput

0.458

High

430441

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

430442

IL7RA
Interleukin-7 receptor subunit alpha

1

0

High-throughput

0.458

High

430443

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

430446

CRCM
Colorectal mutant cancer protein

1

0

High-throughput

0.458

High

430447

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.458

High

430448

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

430450

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

430454

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

430455

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

430457

FOXA1
Hepatocyte nuclear factor 3-alpha

1

0

High-throughput

0.458

High

430459

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.458

High

430461

MERTK
Tyrosine-protein kinase Mer

1

0

High-throughput

0.458

High

430463

SQSTM
Sequestosome-1

1

0

High-throughput

0.458

High

430464

TRI14
Tripartite motif-containing protein 14

1

0

High-throughput

0.458

High

430465

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

0

High-throughput

0.458

High

430466

CUL7
Cullin-7

1

0

High-throughput

0.458

High

430467

EMC2
ER membrane protein complex subunit 2

1

0

High-throughput

0.458

High

430469

FSCN1
Fascin

1

0

High-throughput

0.458

High

430471

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

430480

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.458

High

430481

NIN
Ninein

1

0

High-throughput

0.458

High

430484

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

430486

CHM4C
Charged multivesicular body protein 4c

1

0

High-throughput

0.458

High

430488

BAG1
BAG family molecular chaperone regulator 1

1

0

High-throughput

0.458

High

430489

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.458

High

430490

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.458

High

430491

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

430493

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

430497

TRM7
tRNA

1

0

High-throughput

0.458

High

430498

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

430502

TRAF6
TNF receptor-associated factor 6

1

0

High-throughput

0.458

High

181038

INSI1
Insulin-induced gene 1 protein

1

1

High-throughput

0.437

High

430456

GEM
GTP-binding protein GEM

1

1

High-throughput

0.437

High

430483

CLC4D
C-type lectin domain family 4 member D

1

1

High-throughput

0.437

High

430487

LMTK3
Serine/threonine-protein kinase LMTK3

1

1

High-throughput

0.437

High

430495

TMPS4
Transmembrane protease serine 4

1

1

High-throughput

0.437

High

430499

CLC4E
C-type lectin domain family 4 member E

1

1

High-throughput

0.437

High

430503

INSI2
Insulin-induced gene 2 protein

1

1

High-throughput

0.437

High

430445

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

0

High-throughput

0.426

High

430475

NEK10
Serine/threonine-protein kinase Nek10

1

0

High-throughput

0.426

High

430472

TTC19
Tetratricopeptide repeat protein 19, mitochondrial

2

0

High-throughput

0.316

High

430436

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

328703

TOP3B
DNA topoisomerase 3-beta-1

1

0

High-throughput

0.249

Low

430438

IFM1
Interferon-induced transmembrane protein 1

1

0

High-throughput

0.249

Low

430460

CAV1
Caveolin-1

1

0

High-throughput

0.249

Low

430477

PAQR2
Adiponectin receptor protein 2

1

0

Small-scale

0.249

Low

430501

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024