Protein: NOSIP
Nitric oxide synthase-interacting protein (E3 ubiquitin-protein ligase NOSIP) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase NOSIP) (eNOS-interacting protein)

Gene: NOSIP
Organism: Homo sapiens
Interactions: 85
UniProt ID: Q9Y314

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1459622

DPOLL
DNA polymerase lambda

3

1

High-throughput

0.656

High

387157

TNNC2
Troponin C, skeletal muscle

3

0

High-throughput

0.638

High

1491034

NEUR2
Sialidase-2

3

0

High-throughput

0.638

High

713145

NOS3
Nitric oxide synthase 3

2

1

Small-scale

0.631

High

1371905

CUL5
Cullin-5

2

1

High-throughput

0.628

High

1114712

CUL3
Cullin-3

2

1

High-throughput

0.611

High

911441

IMA5
Importin subunit alpha-5

2

0

Small-scale

0.603

High

1053773

PTN11
Tyrosine-protein phosphatase non-receptor type 11

2

0

High-throughput

0.602

High

373564

MYC
Myc proto-oncogene protein

2

1

High-throughput

0.584

High

1290560

ZN410
Zinc finger protein 410

2

0

High-throughput

0.580

High

994429

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

1

Small-scale

0.578

High

173593

XPO1
Exportin-1

1

3

Small-scale

0.561

High

318177

IPO13
Importin-13

1

4

Small-scale

0.561

High

334946

IPO7
Importin-7

1

3

Small-scale

0.561

High

718059

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

1

Small-scale

0.561

High

1134442

IMB1
Importin subunit beta-1

1

3

Small-scale

0.561

High

1371036

TNPO1
Transportin-1

1

3

Small-scale

0.561

High

386386

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

2

0

High-throughput

0.559

High

165474

RGRF2
Ras-specific guanine nucleotide-releasing factor 2

2

0

High-throughput

0.547

High

1391086

OTUB1
Ubiquitin thioesterase OTUB1

2

0

High-throughput

0.547

High

991131

2ABA
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform

1

0

Small-scale

0.537

High

682658

S100P
Protein S100-P

1

0

High-throughput

0.513

High

867541

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.513

High

928241

HAP1
Huntingtin-associated protein 1

1

0

High-throughput

0.513

High

1310548

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

134190

IPO5
Importin-5

1

2

Small-scale

0.501

High

508873

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

957248

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

0

Small-scale

0.480

High

316192

RECQ4
ATP-dependent DNA helicase Q4

1

1

High-throughput

0.479

High

406822

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

607249

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

713177

NOS1
Nitric oxide synthase 1

1

1

Small-scale

0.479

High

714539

PML
Protein PML

1

1

High-throughput

0.479

High

854960

RECQ1
ATP-dependent DNA helicase Q1

1

1

High-throughput

0.479

High

971329

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

977618

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

1

Small-scale

0.479

High

1100568

TIF1B
Transcription intermediary factor 1-beta

1

1

High-throughput

0.479

High

1227749

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.479

High

1340844

COP1
E3 ubiquitin-protein ligase COP1

1

2

High-throughput

0.479

High

1387657

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

2

High-throughput

0.479

High

1421024

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

1

High-throughput

0.479

High

243357

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

248157

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

260639

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

294901

BCAR3
Breast cancer anti-estrogen resistance protein 3

1

0

High-throughput

0.458

High

346536

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

364069

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.458

High

377792

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.458

High

401736

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

404562

GCR
Glucocorticoid receptor

1

0

High-throughput

0.458

High

414892

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

538157

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

613232

EGR1
Early growth response protein 1

1

0

High-throughput

0.458

High

696930

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

769576

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

791863

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

888409

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

937981

FOXA1
Hepatocyte nuclear factor 3-alpha

1

0

High-throughput

0.458

High

981192

H2B1C
Histone H2B type 1-C/E/F/G/I

1

0

High-throughput

0.458

High

1067865

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.458

High

1089074

TP53B
TP53-binding protein 1

1

0

High-throughput

0.458

High

1097644

CBX3
Chromobox protein homolog 3

1

0

High-throughput

0.458

High

1101113

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.458

High

1138791

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1256197

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1277007

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1313557

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1393849

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

1415915

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

1416966

KLF16
Krueppel-like factor 16

1

0

High-throughput

0.458

High

1434294

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1435484

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1447477

ANLN
Anillin

1

0

High-throughput

0.458

High

1449539

INKA2
PAK4-inhibitor INKA2

1

0

High-throughput

0.458

High

1451331

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.458

High

1453187

WWOX
WW domain-containing oxidoreductase

1

0

High-throughput

0.458

High

1454782

HECW2
E3 ubiquitin-protein ligase HECW2

1

0

High-throughput

0.458

High

1459396

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

430543

JUN
Transcription factor Jun

1

1

High-throughput

0.445

High

1205792

Q5JQP4
DNA polymerase

1

1

High-throughput

0.445

High

1130541

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

0

High-throughput

0.426

High

1226332

CP135
Centrosomal protein of 135 kDa

1

0

High-throughput

0.426

High

887364

CEBPA
CCAAT/enhancer-binding protein alpha

1

1

High-throughput

0.408

High

619233

EPOR
Erythropoietin receptor

1

0

Small-scale

0.249

Low

1410962

ODC
Mitochondrial 2-oxodicarboxylate carrier

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025