Protein: TLCD1
TLC domain-containing protein 1 (Calfacilitin)

Gene: TLCD1
Organism: Homo sapiens
Interactions: 24
UniProt ID: Q96CP7

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0007009 - plasma membrane organization
GO:0055091 - phospholipid homeostasis
GO:0071709 - membrane assembly
GO:0097035 - regulation of membrane lipid distribution

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1386255

S6A15
Sodium-dependent neutral amino acid transporter B(0)AT2

3

3

High-throughput

0.662

High

1132572

FXYD3
FXYD domain-containing ion transport regulator 3

2

1

High-throughput

0.606

High

1350032

SPP2B
Signal peptide peptidase-like 2B

2

0

High-throughput

0.602

High

683306

TNR5
Tumor necrosis factor receptor superfamily member 5

2

0

High-throughput

0.580

High

1142911

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

2

1

High-throughput

0.553

High

1386256

TM14B
Transmembrane protein 14B

2

1

High-throughput

0.553

High

1197853

S39AC
Zinc transporter ZIP12

1

2

High-throughput

0.536

High

174036

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

1

High-throughput

0.489

High

1372360

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

1

High-throughput

0.489

High

1386253

CREL1
Protein disulfide isomerase CRELD1

1

2

High-throughput

0.489

High

722570

CTR1
High affinity cationic amino acid transporter 1

1

1

High-throughput

0.445

High

1139531

S39AE
Metal cation symporter ZIP14

1

2

High-throughput

0.445

High

294147

CD123
Translation initiation factor eIF2 assembly protein

1

2

High-throughput

0.437

High

1238772

TECT3
Tectonic-3

1

3

High-throughput

0.437

High

1386252

TECT2
Tectonic-2

1

3

High-throughput

0.437

High

845098

EAA3
Excitatory amino acid transporter 3

1

0

High-throughput

0.426

High

1363417

S39A7
Zinc transporter SLC39A7

1

2

High-throughput

0.407

High

1109004

AQP6
Aquaporin-6

2

0

High-throughput

0.316

High

1359298

SSMM1
Serine-rich single-pass membrane protein 1

2

0

High-throughput

0.316

High

1384323

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

2

0

High-throughput

0.316

High

1386254

TMM80
Transmembrane protein 80

2

0

High-throughput

0.316

High

1327778

SH2D3
SH2 domain-containing protein 3C

2

0

High-throughput

0.298

High

1386251

BSCL2
Seipin

1

0

High-throughput

0.279

Low

1337900

ZNT7
Zinc transporter 7

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025