Protein: ALKB5
RNA demethylase ALKBH5 (EC 1.14.11.53) (Alkylated DNA repair protein alkB homolog 5) (Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5)

Gene: ALKB5, ALKBH5
Organism: Homo sapiens
Interactions: 41
UniProt ID: Q6P6C2

Gene Ontology (top 5):
GO:0001666 - response to hypoxia
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005794 - Golgi apparatus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

911276

IMA5
Importin subunit alpha-5

3

1

High-throughput

0.662

High

1243126

RBM8A
RNA-binding protein 8A

1

0

High-throughput

0.586

High

1243116

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

2

1

Small-scale

0.584

High

396343

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

385860

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

2

0

High-throughput

0.559

High

1243121

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

0

Small-scale

0.537

High

253644

IMA7
Importin subunit alpha-7

1

1

High-throughput

0.536

High

997796

CSK21
Casein kinase II subunit alpha

1

0

High-throughput

0.527

High

1109149

PRP4K
Serine/threonine-protein kinase PRP4 homolog

1

0

High-throughput

0.513

High

1118064

DX39B
Spliceosome RNA helicase DDX39B

1

0

High-throughput

0.513

High

1233191

THOC7
THO complex subunit 7

1

0

High-throughput

0.513

High

1243113

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1243114

MINK1
Misshapen-like kinase 1

1

0

High-throughput

0.513

High

1243120

E41L5
Band 4.1-like protein 5

1

0

High-throughput

0.513

High

185782

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.480

High

1226893

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.479

High

1243115

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

1243118

UBP47
Ubiquitin carboxyl-terminal hydrolase 47

1

1

Small-scale

0.479

High

315696

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

401008

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

414043

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

424421

HMGN1
Non-histone chromosomal protein HMG-14

1

0

High-throughput

0.458

High

558211

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.458

High

934753

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

937789

FOXA1
Hepatocyte nuclear factor 3-alpha

1

0

High-throughput

0.458

High

980856

H2B1C
Histone H2B type 1-C/E/F/G/I

1

0

High-throughput

0.458

High

1024642

VIGLN
Vigilin

1

0

High-throughput

0.458

High

1107839

SQSTM
Sequestosome-1

1

0

High-throughput

0.458

High

1198575

NCBP3
Nuclear cap-binding protein subunit 3

1

0

High-throughput

0.458

High

1243119

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

1243123

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1243125

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

430048

JUN
Transcription factor Jun

1

0

High-throughput

0.426

High

1226137

CP135
Centrosomal protein of 135 kDa

1

0

High-throughput

0.426

High

886965

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.391

High

1243124

EPCR
Endothelial protein C receptor

1

0

High-throughput

0.269

Low

377611

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

1243111

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1243112

UBP53
Ubiquitin carboxyl-terminal hydrolase 53

1

0

Small-scale

0.249

Low

1243117

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

1243122

HECW2
E3 ubiquitin-protein ligase HECW2

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025