HitPredict - High confidence protein-protein interactions

Protein: CAR16
Caspase recruitment domain-containing protein 16 (Caspase recruitment domain-only protein 1) (CARD-only protein 1) (Caspase-1 inhibitor COP) (Pseudo interleukin-1 beta converting enzyme) (Pseudo-ICE) (Pseudo-IL1B-converting enzyme)

Gene: CAR16, CARD16
Organism: Homo sapiens
Interactions: 11
UniProt ID: Q5EG05

Gene Ontology (top 5):
GO:0004197 - cysteine-type endopeptidase activity
GO:0004869 - cysteine-type endopeptidase inhibitor activity
GO:0006508 - proteolysis
GO:0010804 - negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0019900 - kinase binding

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
712872	CASP1 Caspase-1	2	17	Small-scale	0.789	High
214437	RIPK2 Receptor-interacting serine/threonine-protein kinase 2	2	2	Small-scale	0.776	High
1204248	CAR16 Caspase recruitment domain-containing protein 16	1	10	Small-scale	0.618	High
1204253	CARD8 Caspase recruitment domain-containing protein 8	1	5	Small-scale	0.618	High
508089	UBC Polyubiquitin-C [Cleaved into: Ubiquitin]	1	0	High-throughput	0.541	High
1204250	FAT4 Protocadherin Fat 4	1	1	High-throughput	0.489	High
1204251	FAT3 Protocadherin Fat 3	1	1	High-throughput	0.489	High
631261	RAB5A Ras-related protein Rab-5A	1	3	Small-scale	0.437	High
1204249	HERC4 Probable E3 ubiquitin-protein ligase HERC4	1	0	High-throughput	0.279	Low
1204252	TRIB2 Tribbles homolog 2	1	0	Small-scale	0.232	Low

Service provided by Combinatics, Japan

Last updated: 11Aug2025