Protein: ITIH3
Inter-alpha-trypsin inhibitor heavy chain H3 (ITI heavy chain H3) (ITI-HC3) (Inter-alpha-inhibitor heavy chain 3) (Serum-derived hyaluronan-associated protein) (SHAP)

Gene: ITIH3
Organism: Homo sapiens
Interactions: 26
UniProt ID: Q06033

Gene Ontology (top 5):
GO:0004866 - endopeptidase inhibitor activity
GO:0004867 - serine-type endopeptidase inhibitor activity
GO:0005576 - extracellular region
GO:0030212 - hyaluronan metabolic process
GO:0031089 - platelet dense granule lumen

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

303707

CYTF
Cystatin-F

2

2

High-throughput

0.628

High

1022080

TSG6
Tumor necrosis factor-inducible gene 6 protein

2

2

Small-scale

0.619

High

369861

CO3
Complement C3

1

3

High-throughput

0.618

High

1053489

LRC47
Leucine-rich repeat-containing protein 47

1

0

High-throughput

0.578

High

606063

KCNA6
Potassium voltage-gated channel subfamily A member 6

1

1

High-throughput

0.553

High

573445

ENPL
Endoplasmin

1

3

High-throughput

0.536

High

1053485

TBB8
Tubulin beta-8 chain

1

3

High-throughput

0.536

High

921367

MAP11
Methionine aminopeptidase 1

1

1

High-throughput

0.489

High

1053491

TXD15
Thioredoxin domain-containing protein 15

1

3

High-throughput

0.489

High

634963

NTF3
Neurotrophin-3

1

0

High-throughput

0.458

High

529682

TAU
Microtubule-associated protein tau

1

5

Small-scale

0.445

High

1053495

ITM2B
Integral membrane protein 2B

1

4

High-throughput

0.445

High

1053482

EP300
Histone acetyltransferase p300

1

2

High-throughput

0.439

High

218091

TGON2
Trans-Golgi network integral membrane protein 2

1

4

High-throughput

0.437

High

277289

PITX3
Pituitary homeobox 3

1

2

Small-scale

0.437

High

400698

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.437

High

1053483

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.437

High

1053484

PTN14
Tyrosine-protein phosphatase non-receptor type 14

1

3

High-throughput

0.437

High

1053494

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.437

High

1053492

THTPA
Thiamine-triphosphatase

2

0

High-throughput

0.318

High

1053488

IKIP
Inhibitor of nuclear factor kappa-B kinase-interacting protein

1

0

High-throughput

0.279

Low

293600

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

1053486

MIDN
Midnolin

1

0

High-throughput

0.249

Low

1053490

CHM4C
Charged multivesicular body protein 4c

1

0

High-throughput

0.249

Low

1053493

NGB
Neuroglobin

1

0

High-throughput

0.249

Low

1053487

MFSD6
Major facilitator superfamily domain-containing protein 6

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025