Protein: TSG6
Tumor necrosis factor-inducible gene 6 protein (EC 3.1.1.-) (Hyaluronate-binding protein) (TNF-stimulated gene 6 protein) (TSG-6) (Tumor necrosis factor alpha-induced protein 6) (TNF alpha-induced protein 6)

Gene: TSG6, TNFAIP6
Organism: Homo sapiens
Interactions: 50
UniProt ID: P98066

Gene Ontology (top 5):
GO:0001550 - ovarian cumulus expansion
GO:0001968 - fibronectin binding
GO:0005509 - calcium ion binding
GO:0005540 - hyaluronic acid binding
GO:0005576 - extracellular region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

565098

CSPG2
Versican core protein

1

12

High-throughput

0.691

High

1022079

LRP2
Low-density lipoprotein receptor-related protein 2

1

2

High-throughput

0.691

High

158946

CXL11
C-X-C motif chemokine 11

2

6

Small-scale

0.619

High

625994

ITIH2
Inter-alpha-trypsin inhibitor heavy chain H2

2

2

Small-scale

0.619

High

1022080

ITIH3
Inter-alpha-trypsin inhibitor heavy chain H3

2

2

Small-scale

0.619

High

562889

CCL5
C-C motif chemokine 5

2

15

Small-scale

0.602

High

464437

TSP1
Thrombospondin-1

2

8

Small-scale

0.595

High

164685

TNF11
Tumor necrosis factor ligand superfamily member 11

1

1

Small-scale

0.536

High

389287

FINC
Fibronectin

1

12

Small-scale

0.536

High

478461

FGF2
Fibroblast growth factor 2

1

1

Small-scale

0.536

High

518776

IL8
Interleukin-8

1

4

Small-scale

0.536

High

554128

BMP2
Bone morphogenetic protein 2

1

14

Small-scale

0.536

High

562845

CCL2
C-C motif chemokine 2

1

15

Small-scale

0.536

High

845230

GDF5
Growth/differentiation factor 5

1

16

Small-scale

0.536

High

1009606

CCL7
C-C motif chemokine 7

1

15

Small-scale

0.536

High

1022086

GDF6
Growth/differentiation factor 6

1

14

Small-scale

0.536

High

1022094

CCL19
C-C motif chemokine 19

1

15

Small-scale

0.536

High

683721

PTX3
Pentraxin-related protein PTX3

1

0

Small-scale

0.513

High

1022093

THOC1
THO complex subunit 1

1

0

High-throughput

0.513

High

141752

CCL21
C-C motif chemokine 21

1

15

Small-scale

0.501

High

390367

PLF4
Platelet factor 4

1

4

Small-scale

0.501

High

507837

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

1

High-throughput

0.501

High

554210

BMP4
Bone morphogenetic protein 4

1

16

Small-scale

0.501

High

611719

BMP7
Bone morphogenetic protein 7

1

16

Small-scale

0.501

High

626051

ITIH1
Inter-alpha-trypsin inhibitor heavy chain H1

1

2

Small-scale

0.501

High

643185

BMP5
Bone morphogenetic protein 5

1

16

Small-scale

0.501

High

643193

BMP6
Bone morphogenetic protein 6

1

16

Small-scale

0.501

High

870200

SDF1
Stromal cell-derived factor 1

1

1

Small-scale

0.501

High

1022082

KIF7
Kinesin-like protein KIF7

1

1

High-throughput

0.489

High

1022083

KCD21
BTB/POZ domain-containing protein KCTD21

1

8

High-throughput

0.489

High

1022091

RN166
E3 ubiquitin-protein ligase RNF166

1

2

High-throughput

0.489

High

1022092

F120B
Constitutive coactivator of peroxisome proliferator-activated receptor gamma

1

1

High-throughput

0.489

High

1022101

CCL27
C-C motif chemokine 27

1

0

Small-scale

0.480

High

590875

TIMP2
Metalloproteinase inhibitor 2

1

1

High-throughput

0.479

High

277288

PITX3
Pituitary homeobox 3

1

3

Small-scale

0.437

High

1022100

XPO7
Exportin-7

1

1

High-throughput

0.437

High

345172

ZMYM6
Zinc finger MYM-type protein 6

1

0

High-throughput

0.279

Low

702515

ACADL
Long-chain specific acyl-CoA dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

1022081

THOC5
THO complex subunit 5

1

0

High-throughput

0.279

Low

1022084

F91A1
Protein FAM91A1

1

0

High-throughput

0.279

Low

1022085

THOC7
THO complex subunit 7

1

0

High-throughput

0.279

Low

1022087

FXRD2
FAD-dependent oxidoreductase domain-containing protein 2

1

0

High-throughput

0.279

Low

1022088

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

1

0

High-throughput

0.279

Low

1022089

SUV3
ATP-dependent RNA helicase SUPV3L1, mitochondrial

1

0

High-throughput

0.279

Low

1022090

AT2L1
Ethanolamine-phosphate phospho-lyase

1

0

High-throughput

0.279

Low

1022095

WDR11
WD repeat-containing protein 11

1

0

High-throughput

0.279

Low

1022096

NJMU
Protein Njmu-R1

1

0

High-throughput

0.279

Low

1022097

PYRG2
CTP synthase 2

1

0

High-throughput

0.279

Low

1022098

TBC23
TBC1 domain family member 23

1

0

High-throughput

0.279

Low

1022099

TXD16
Thioredoxin domain-containing protein 16

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025