Protein: PITX3
Pituitary homeobox 3 (Homeobox protein PITX3) (Paired-like homeodomain transcription factor 3)

Gene: PITX3
Organism: Homo sapiens
Interactions: 89
UniProt ID: O75364

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0002088 - lens development in camera-type eye

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

277222

AACT
Alpha-1-antichymotrypsin

1

3

Small-scale

0.479

High

277233

K1C14
Keratin, type I cytoskeletal 14

1

9

Small-scale

0.479

High

277235

APOE
Apolipoprotein E

1

1

Small-scale

0.479

High

277239

SAMP
Serum amyloid P-component

1

1

Small-scale

0.479

High

277251

K2C1
Keratin, type II cytoskeletal 1

1

3

Small-scale

0.479

High

277258

K1C16
Keratin, type I cytoskeletal 16

1

9

Small-scale

0.479

High

277262

CLUS
Clusterin

1

1

Small-scale

0.479

High

277265

K1C10
Keratin, type I cytoskeletal 10

1

7

Small-scale

0.479

High

277266

K2C5
Keratin, type II cytoskeletal 5

1

3

Small-scale

0.479

High

277273

SFPQ
Splicing factor, proline- and glutamine-rich

1

8

Small-scale

0.479

High

277276

K1C9
Keratin, type I cytoskeletal 9

1

10

Small-scale

0.479

High

277278

MYH9
Myosin-9

1

2

Small-scale

0.479

High

277279

K22E
Keratin, type II cytoskeletal 2 epidermal

1

4

Small-scale

0.479

High

277284

ACTB
Actin, cytoplasmic 1

1

1

Small-scale

0.479

High

277292

NONO
Non-POU domain-containing octamer-binding protein

1

8

Small-scale

0.479

High

277294

FILA2
Filaggrin-2

1

13

Small-scale

0.479

High

277296

HORN
Hornerin

1

9

Small-scale

0.479

High

277271

CAP7
Azurocidin

1

2

Small-scale

0.470

High

128667

MEN1
Menin

1

0

High-throughput

0.458

High

277245

ALBU
Albumin

1

0

Small-scale

0.458

High

277252

PERM
Myeloperoxidase

1

0

Small-scale

0.458

High

277272

H2A1D
Histone H2A type 1-D

1

0

Small-scale

0.458

High

277285

H2B1C
Histone H2B type 1-C/E/F/G/I

1

0

Small-scale

0.458

High

125797

MASP2
Mannan-binding lectin serine protease 2

1

4

Small-scale

0.437

High

230146

CD5L
CD5 antigen-like

1

1

Small-scale

0.437

High

277213

FCN3
Ficolin-3

1

5

Small-scale

0.437

High

277215

CERU
Ceruloplasmin

1

1

Small-scale

0.437

High

277216

THRB
Prothrombin

1

3

Small-scale

0.437

High

277217

HPTR
Haptoglobin-related protein

1

4

Small-scale

0.437

High

277218

FA10
Coagulation factor X

1

2

Small-scale

0.437

High

277219

CFAB
Complement factor B

1

4

Small-scale

0.437

High

277220

ANT3
Antithrombin-III

1

4

Small-scale

0.437

High

277221

A1AT
Alpha-1-antitrypsin

1

4

Small-scale

0.437

High

277223

A2MG
Alpha-2-macroglobulin

1

3

Small-scale

0.437

High

277224

CO3
Complement C3

1

3

Small-scale

0.437

High

277225

CO5
Complement C5

1

3

Small-scale

0.437

High

277226

KNG1
Kininogen-1

1

2

Small-scale

0.437

High

277229

IGKC
Immunoglobulin kappa constant

1

4

Small-scale

0.437

High

277230

IGHG1
Immunoglobulin heavy constant gamma 1

1

4

Small-scale

0.437

High

277231

IGHG2
Immunoglobulin heavy constant gamma 2

1

4

Small-scale

0.437

High

277232

IGHA1
Immunoglobulin heavy constant alpha 1

1

3

Small-scale

0.437

High

277234

APOA1
Apolipoprotein A-I

1

1

Small-scale

0.437

High

277236

FIBA
Fibrinogen alpha chain [Cleaved into: Fibrinopeptide A; Fibrinogen alpha chain]

1

5

Small-scale

0.437

High

277237

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

1

5

Small-scale

0.437

High

277238

FIBG
Fibrinogen gamma chain

1

5

Small-scale

0.437

High

277240

C1QA
Complement C1q subcomponent subunit A

1

1

Small-scale

0.437

High

277241

C1QB
Complement C1q subcomponent subunit B

1

2

Small-scale

0.437

High

277242

AMBP
Protein AMBP

1

5

Small-scale

0.437

High

277243

FETUA
Alpha-2-HS-glycoprotein

1

2

Small-scale

0.437

High

277247

FA11
Coagulation factor XI

1

1

Small-scale

0.437

High

277248

C4BPA
C4b-binding protein alpha chain

1

3

Small-scale

0.437

High

277249

APOB
Apolipoprotein B-100

1

2

Small-scale

0.437

High

277250

HRG
Histidine-rich glycoprotein

1

7

Small-scale

0.437

High

277253

HEP2
Heparin cofactor 2

1

3

Small-scale

0.437

High

277255

PROS
Vitamin K-dependent protein S

1

3

Small-scale

0.437

High

277256

TSP1
Thrombospondin-1

1

3

Small-scale

0.437

High

277257

CFAH
Complement factor H

1

2

Small-scale

0.437

High

277259

CO4B
Complement C4-B

1

3

Small-scale

0.437

High

277260

SAA1
Serum amyloid A-1 protein

1

1

Small-scale

0.437

High

277261

TFPI1
Tissue factor pathway inhibitor

1

5

Small-scale

0.437

High

277263

FA5
Coagulation factor V

1

7

Small-scale

0.437

High

277264

CSPG2
Versican core protein

1

3

Small-scale

0.437

High

277269

ITIH2
Inter-alpha-trypsin inhibitor heavy chain H2

1

2

Small-scale

0.437

High

277270

ITIH1
Inter-alpha-trypsin inhibitor heavy chain H1

1

2

Small-scale

0.437

High

277275

PROP
Properdin

1

1

Small-scale

0.437

High

277277

SAA4
Serum amyloid A-4 protein

1

1

Small-scale

0.437

High

277281

K2C6C
Keratin, type II cytoskeletal 6C

1

3

Small-scale

0.437

High

277282

MASP1
Mannan-binding lectin serine protease 1

1

3

Small-scale

0.437

High

277286

HBB
Hemoglobin subunit beta

1

2

Small-scale

0.437

High

277287

HBA
Hemoglobin subunit alpha

1

2

Small-scale

0.437

High

277288

TSG6
Tumor necrosis factor-inducible gene 6 protein

1

3

Small-scale

0.437

High

277289

ITIH3
Inter-alpha-trypsin inhibitor heavy chain H3

1

2

Small-scale

0.437

High

277291

MMRN1
Multimerin-1

1

3

Small-scale

0.437

High

277293

FCN2
Ficolin-2

1

5

Small-scale

0.437

High

277295

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

3

High-throughput

0.437

High

277298

COL11
Collectin-11

1

1

Small-scale

0.437

High

277214

CAVN2
Caveolae-associated protein 2

1

0

Small-scale

0.249

Low

277227

IGJ
Immunoglobulin J chain

1

0

Small-scale

0.249

Low

277228

PIGR
Polymeric immunoglobulin receptor

1

0

Small-scale

0.249

Low

277244

TTHY
Transthyretin

1

0

Small-scale

0.249

Low

277246

PLF4
Platelet factor 4

1

0

Small-scale

0.249

Low

277254

KV401
Immunoglobulin kappa variable 4-1

1

0

Small-scale

0.249

Low

277267

LBP
Lipopolysaccharide-binding protein

1

0

Small-scale

0.249

Low

277268

A1AG2
Alpha-1-acid glycoprotein 2

1

0

Small-scale

0.249

Low

277274

PON1
Serum paraoxonase/arylesterase 1

1

0

Small-scale

0.249

Low

277280

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

1

0

Small-scale

0.249

Low

277283

DEF1
Neutrophil defensin 1

1

0

Small-scale

0.249

Low

277290

SPP24
Secreted phosphoprotein 24

1

0

Small-scale

0.249

Low

277297

ITLN1
Intelectin-1

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025