Protein: VPS10
Vacuolar protein sorting/targeting protein VPS10 (Carboxypeptidase Y receptor) (CPY receptor) (Carboxypeptidase Y-deficient protein 1) (Sortilin VPS10) (Vacuolar carboxypeptidase sorting receptor VPS10) (Vacuolar protein sorting-associated protein 10) (Vacuolar protein-targeting protein 1)

Gene: VPS10, PEP1
Organism: Saccharomyces cerevisiae S288C
Interactions: 59
UniProt ID: P32319

Gene Ontology (top 5):
GO:0000166 - nucleotide binding
GO:0000324 - fungal-type vacuole
GO:0000423 - mitophagy
GO:0000425 - pexophagy
GO:0005048 - signal sequence binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

687087

VPS10
Vacuolar protein sorting/targeting protein VPS10

2

4

High-throughput

0.811

High

687089

VPS35
Vacuolar protein sorting-associated protein 35

2

2

Small-scale

0.614

High

687100

PEP8
Carboxypeptidase Y-deficient protein 8

2

1

Small-scale

0.614

High

687103

ATG27
Autophagy-related protein 27

2

1

High-throughput

0.614

High

687096

GGA2
ADP-ribosylation factor-binding protein GGA2

2

7

Small-scale

0.613

High

687121

VPS68
Vacuolar protein sorting-associated protein 68

2

0

High-throughput

0.588

High

687125

VPS5
Vacuolar protein sorting-associated protein 5

2

0

Small-scale

0.588

High

687112

ANY1
Scramblase ANY1

2

0

High-throughput

0.587

High

490599

HSP71
Heat shock protein SSA1

2

2

High-throughput

0.571

High

510562

SSB1
Ribosome-associated molecular chaperone SSB1

2

4

High-throughput

0.552

High

389696

CDC25
Cell division control protein 25

1

1

High-throughput

0.541

High

452520

KEX1
Pheromone-processing carboxypeptidase KEX1

1

0

High-throughput

0.518

High

604363

CLH
Clathrin heavy chain

1

0

High-throughput

0.518

High

687105

ENT3
Epsin-3

1

0

High-throughput

0.518

High

687124

LAS17
Proline-rich protein LAS17

1

1

High-throughput

0.489

High

687116

VTI1
t-SNARE VTI1

1

0

Small-scale

0.484

High

425187

CARP
Saccharopepsin

1

1

Small-scale

0.479

High

543367

HSC82
ATP-dependent molecular chaperone HSC82

1

2

High-throughput

0.479

High

608932

VPS34
Phosphatidylinositol 3-kinase VPS34

1

2

High-throughput

0.479

High

687110

BECN1
Vacuolar protein sorting-associated protein 30

1

1

High-throughput

0.479

High

687115

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.479

High

687122

ATG9
Autophagy-related protein 9

1

1

High-throughput

0.479

High

606242

VPS15
Serine/threonine-protein kinase VPS15

1

0

High-throughput

0.458

High

687101

SEC24
Protein transport protein SEC24

1

0

High-throughput

0.458

High

687104

VPS53
Vacuolar protein sorting-associated protein 53

1

0

Small-scale

0.458

High

687108

DID2
Vacuolar protein-sorting-associated protein 46

1

0

High-throughput

0.458

High

687119

ATG20
Autophagy-related protein 20

1

1

High-throughput

0.457

High

687095

SSZ1
Ribosome-associated complex subunit SSZ1

1

1

High-throughput

0.445

High

687099

SSB2
Ribosome-associated molecular chaperone SSB2

1

4

High-throughput

0.445

High

524214

CAF20
Cap-associated protein CAF20

1

2

High-throughput

0.437

High

566144

EST1
Telomere elongation protein EST1

1

2

High-throughput

0.437

High

572028

CLC1
Clathrin light chain

1

1

Small-scale

0.437

High

572747

PDI
Protein disulfide-isomerase

1

2

High-throughput

0.437

High

660296

PEX3
Peroxisomal biogenesis factor 3

1

1

High-throughput

0.437

High

687091

CENPA
Histone H3-like centromeric protein CSE4

1

5

High-throughput

0.437

High

367836

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

687088

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.426

High

687120

TLG2
t-SNARE affecting a late Golgi compartment protein 2

1

0

Small-scale

0.426

High

356313

H4
Histone H4

1

1

High-throughput

0.407

High

687109

NOP3
Serine/arginine

2

0

High-throughput

0.324

High

687111

DIG1
Down-regulator of invasive growth 1

2

0

High-throughput

0.324

High

687090

DEF1
RNA polymerase II degradation factor 1

2

0

High-throughput

0.298

High

687093

FTH1
Iron transporter FTH1

1

0

High-throughput

0.282

High

687102

BUD27
Bud site selection protein 27

1

0

Small-scale

0.282

High

687114

TVP15
Golgi apparatus membrane protein TVP15

1

0

High-throughput

0.282

High

687123

RPN6
26S proteasome regulatory subunit RPN6

1

0

High-throughput

0.269

Low

474327

U5072
UPF0507 protein YML002W

1

0

Small-scale

0.251

Low

661585

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

687092

HMT1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.249

Low

687094

ECM29
Proteasome component ECM29

1

0

High-throughput

0.249

Low

687097

SNF7
Vacuolar-sorting protein SNF7

1

0

High-throughput

0.249

Low

687106

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

687107

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.249

Low

687113

BUL2
Ubiquitin ligase-binding protein BUL2

1

0

Small-scale

0.249

Low

687117

SEC13
Protein transport protein SEC13

1

0

High-throughput

0.249

Low

687118

ATG23
Autophagy-related protein 23

1

0

High-throughput

0.249

Low

440867

ARO1
Pentafunctional AROM polypeptide [Includes: 3-dehydroquinate synthase

1

0

High-throughput

0.232

Low

687098

HSP7E
Heat shock protein SSC3, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024