Protein: NEC1
Neuroendocrine convertase 1 (NEC 1) (EC 3.4.21.93) (Prohormone convertase 1) (Proprotein convertase 1) (PC1)

Gene: NEC1, PCSK1
Organism: Homo sapiens
Interactions: 12
UniProt ID: P29120

Gene Ontology (top 5):
GO:0004252 - serine-type endopeptidase activity
GO:0005615 - extracellular space
GO:0006508 - proteolysis
GO:0007267 - cell-cell signaling
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

709048

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

3

High-throughput

0.489

High

709049

DCAF6
DDB1- and CUL4-associated factor 6

1

3

High-throughput

0.489

High

377416

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.458

High

709047

AFF1
AF4/FMR2 family member 1

1

1

Small-scale

0.437

High

239483

H6ST1
Heparan-sulfate 6-O-sulfotransferase 1

1

0

High-throughput

0.279

Low

625985

ITIH2
Inter-alpha-trypsin inhibitor heavy chain H2

1

0

High-throughput

0.279

Low

709045

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

0

High-throughput

0.279

Low

709046

ACDSB
Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

709050

DHRS6
Dehydrogenase/reductase SDR family member 6

1

0

High-throughput

0.279

Low

709051

ABCB6
ATP-binding cassette sub-family B member 6

1

0

High-throughput

0.279

Low

709052

B4GT6
Beta-1,4-galactosyltransferase 6

1

0

High-throughput

0.279

Low

595955

H12
Histone H1.2

1

0

High-throughput

0.269

Low


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Last updated: 11Aug2025