Protein: ACDSB
Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial (SBCAD) (EC 1.3.8.5) (2-methyl branched chain acyl-CoA dehydrogenase) (2-MEBCAD) (2-methylbutyryl-coenzyme A dehydrogenase) (2-methylbutyryl-CoA dehydrogenase)

Gene: ACDSB, ACADSB
Organism: Homo sapiens
Interactions: 71
UniProt ID: P45954

Gene Ontology (top 5):
GO:0003853 - short-chain 2-methyl fatty acyl-CoA dehydrogenase activity
GO:0003995 - acyl-CoA dehydrogenase activity
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006550 - L-isoleucine catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

853102

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

3

4

Small-scale

0.640

High

853112

HSC20
Iron-sulfur cluster co-chaperone protein HscB

2

3

High-throughput

0.611

High

241005

PRKN
E3 ubiquitin-protein ligase parkin

2

7

High-throughput

0.584

High

403902

GCR
Glucocorticoid receptor

2

4

Small-scale

0.584

High

322913

UBP19
Ubiquitin carboxyl-terminal hydrolase 19

1

2

High-throughput

0.489

High

853117

THOC2
THO complex subunit 2

1

2

High-throughput

0.489

High

853136

SNTG1
Gamma-1-syntrophin

1

3

High-throughput

0.489

High

853145

SAR1B
Small COPII coat GTPase SAR1B

1

3

High-throughput

0.489

High

279689

CISY
Citrate synthase, mitochondrial

1

6

High-throughput

0.479

High

400449

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

3

High-throughput

0.479

High

470910

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

6

High-throughput

0.479

High

519074

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

3

High-throughput

0.479

High

532435

CH60
60 kDa heat shock protein, mitochondrial

1

4

High-throughput

0.479

High

766286

PHB1
Prohibitin 1

1

3

High-throughput

0.479

High

851835

EFTS
Elongation factor Ts, mitochondrial

1

4

High-throughput

0.479

High

853097

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

2

High-throughput

0.479

High

853101

PDK1
[Pyruvate dehydrogenase

1

6

High-throughput

0.479

High

853105

SYAM
Alanine--tRNA ligase, mitochondrial

1

3

High-throughput

0.479

High

853108

MRM1
rRNA methyltransferase 1, mitochondrial

1

3

High-throughput

0.479

High

853126

IMP1L
Mitochondrial inner membrane protease subunit 1

1

6

High-throughput

0.479

High

853127

IMP2L
Mitochondrial inner membrane protease subunit 2

1

6

High-throughput

0.479

High

853128

TR61B
tRNA

1

3

High-throughput

0.479

High

853131

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

1

High-throughput

0.479

High

853138

WWOX
WW domain-containing oxidoreductase

1

4

High-throughput

0.479

High

853099

GOGA4
Golgin subfamily A member 4

1

3

High-throughput

0.470

High

853106

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

4

High-throughput

0.445

High

362939

EGFR
Epidermal growth factor receptor

1

2

High-throughput

0.437

High

830296

CCNF
Cyclin-F

1

3

High-throughput

0.437

High

853094

DRG2
Developmentally-regulated GTP-binding protein 2

1

7

High-throughput

0.437

High

853095

TERA
Transitional endoplasmic reticulum ATPase

1

1

High-throughput

0.437

High

853103

CL16A
Protein CLEC16A

1

1

High-throughput

0.437

High

853107

FTM
Protein fantom

1

4

High-throughput

0.437

High

853110

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.437

High

853111

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.437

High

853118

FBF1
Fas-binding factor 1

1

4

High-throughput

0.437

High

853121

FAF2
FAS-associated factor 2

1

3

High-throughput

0.437

High

853124

RPGR1
X-linked retinitis pigmentosa GTPase regulator-interacting protein 1

1

4

High-throughput

0.437

High

853125

CI072
Guanine nucleotide exchange factor C9orf72

1

2

High-throughput

0.437

High

853130

SPRTN
DNA-dependent metalloprotease SPRTN

1

1

High-throughput

0.437

High

853132

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.437

High

853133

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.437

High

853137

TLS1
Splicing factor C9orf78

1

3

High-throughput

0.437

High

853139

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.437

High

853142

DRG1
Developmentally-regulated GTP-binding protein 1

1

7

High-throughput

0.437

High

540995

PIM1
Serine/threonine-protein kinase pim-1

1

3

High-throughput

0.407

High

754008

CD80
T-lymphocyte activation antigen CD80

1

1

High-throughput

0.407

High

853096

VMAT2
Synaptic vesicular amine transporter

1

2

High-throughput

0.407

High

853098

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

5

High-throughput

0.407

High

853115

MFSD9
Major facilitator superfamily domain-containing protein 9

1

1

High-throughput

0.407

High

853116

MOT11
Monocarboxylate transporter 11

1

3

High-throughput

0.407

High

853120

SO4A1
Solute carrier organic anion transporter family member 4A1

1

2

High-throughput

0.407

High

853122

AURKB
Aurora kinase B

1

3

High-throughput

0.407

High

853140

XCT
Cystine/glutamate transporter

1

3

High-throughput

0.407

High

853141

ITM2B
Integral membrane protein 2B

1

3

High-throughput

0.407

High

853143

S35A3
UDP-N-acetylglucosamine transporter

1

1

High-throughput

0.407

High

709046

NEC1
Neuroendocrine convertase 1

1

0

High-throughput

0.279

Low

853113

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.279

Low

853123

M4A4A
Membrane-spanning 4-domains subfamily A member 4A

1

0

High-throughput

0.279

Low

853119

PXDN
Peroxidasin homolog

1

0

High-throughput

0.269

Low

208475

PJA2
E3 ubiquitin-protein ligase Praja-2

1

0

Small-scale

0.249

Low

227417

SPOP
Speckle-type POZ protein

1

0

High-throughput

0.249

Low

787120

BMR1A
Bone morphogenetic protein receptor type-1A

1

0

High-throughput

0.249

Low

853100

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.249

Low

853104

SMU1
WD40 repeat-containing protein SMU1

1

0

High-throughput

0.249

Low

853109

TECT3
Tectonic-3

1

0

High-throughput

0.249

Low

853114

CGAS
Cyclic GMP-AMP synthase

1

0

Small-scale

0.249

Low

853129

YTHD1
YTH domain-containing family protein 1

1

0

High-throughput

0.249

Low

853144

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

139193

UPK2
Uroplakin-2

1

0

High-throughput

0.232

Low

853134

S38AA
Solute carrier family 38 member 10

1

0

High-throughput

0.232

Low

853135

S17A5
Sialin

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025