Protein: RNH2A
Ribonuclease H2 subunit A (RNase H2 subunit A) (EC 3.1.26.4) (Aicardi-Goutieres syndrome 4 protein) (AGS4) (RNase H(35)) (Ribonuclease HI large subunit) (RNase HI large subunit) (Ribonuclease HI subunit A)

Gene: RNH2A, RNASEH2A
Organism: Homo sapiens
Interactions: 63
UniProt ID: O75792

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0004523 - RNA-DNA hybrid ribonuclease activity
GO:0004540 - RNA nuclease activity
GO:0005654 - nucleoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

292911

RNH2B
Ribonuclease H2 subunit B

3

1

Small-scale

0.855

High

292919

RNH2C
Ribonuclease H2 subunit C

3

0

High-throughput

0.827

High

292890

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.656

High

292889

BPNT1
3'(2'),5'-bisphosphate nucleotidase 1

2

0

High-throughput

0.602

High

292903

RAD51
DNA repair protein RAD51 homolog 1

2

0

Small-scale

0.585

High

292899

BRCA2
Breast cancer type 2 susceptibility protein

1

0

Small-scale

0.537

High

258684

DNJA2
DnaJ homolog subfamily A member 2

1

1

High-throughput

0.536

High

292893

DNJA1
DnaJ homolog subfamily A member 1

1

1

High-throughput

0.536

High

71421

P20L1
PHD finger protein 20-like protein 1

1

0

High-throughput

0.513

High

211464

PAPS1
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1

1

0

High-throughput

0.513

High

216590

HTRA2
Serine protease HTRA2, mitochondrial

1

0

High-throughput

0.513

High

292894

I5P2
Type II inositol 1,4,5-trisphosphate 5-phosphatase

1

0

High-throughput

0.513

High

292895

PRDX2
Peroxiredoxin-2

1

0

High-throughput

0.513

High

292897

FEN1
Flap endonuclease 1

1

0

High-throughput

0.513

High

292905

DX39B
Spliceosome RNA helicase DDX39B

1

0

High-throughput

0.513

High

292909

TTF1
Transcription termination factor 1

1

0

High-throughput

0.513

High

292912

PSRC1
Proline/serine-rich coiled-coil protein 1

1

0

High-throughput

0.513

High

292916

CS047
Uncharacterized protein C19orf47

1

0

High-throughput

0.513

High

292917

INADL
InaD-like protein

1

0

High-throughput

0.513

High

292918

RIN3
Ras and Rab interactor 3

1

0

High-throughput

0.513

High

292921

OSBP2
Oxysterol-binding protein 2

1

0

High-throughput

0.513

High

292923

DOCK6
Dedicator of cytokinesis protein 6

1

0

High-throughput

0.513

High

292927

UIF
UAP56-interacting factor

1

0

High-throughput

0.513

High

292931

PDIP3
Polymerase delta-interacting protein 3

1

0

High-throughput

0.513

High

292932

DUS16
Dual specificity protein phosphatase 16

1

0

High-throughput

0.513

High

292933

SIAS
N-acetylneuraminate-9-phosphate synthase

1

0

High-throughput

0.513

High

292936

DECR2
Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]

1

0

High-throughput

0.513

High

292942

HEMK2
Methyltransferase HEMK2

1

0

High-throughput

0.513

High

292943

NUBP2
Cytosolic Fe-S cluster assembly factor NUBP2

1

0

High-throughput

0.513

High

292915

KLH36
Kelch-like protein 36

1

1

High-throughput

0.489

High

292925

IMP1L
Mitochondrial inner membrane protease subunit 1

1

1

High-throughput

0.489

High

292928

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.489

High

292934

KLHL1
Kelch-like protein 1

1

1

High-throughput

0.489

High

292892

TNR6
Tumor necrosis factor receptor superfamily member 6

1

1

High-throughput

0.479

High

292891

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

292896

BRCA1
Breast cancer type 1 susceptibility protein

1

0

Small-scale

0.458

High

292898

SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

1

0

High-throughput

0.458

High

292900

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

292901

H2B1C
Histone H2B type 1-C/E/F/G/I

1

0

High-throughput

0.458

High

292902

H31
Histone H3.1

1

0

High-throughput

0.458

High

292904

CUL3
Cullin-3

1

0

High-throughput

0.458

High

292906

SAFB2
Scaffold attachment factor B2

1

0

High-throughput

0.458

High

292914

PALB2
Partner and localizer of BRCA2

1

0

Small-scale

0.458

High

292924

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

292937

UBQL2
Ubiquilin-2

1

0

High-throughput

0.458

High

292938

FBW1B
F-box/WD repeat-containing protein 11

1

0

High-throughput

0.458

High

114539

H0YHG0
DnaJ homolog subfamily C member 14

1

2

High-throughput

0.407

High

292944

KPTN
KICSTOR complex protein kaptin

3

0

High-throughput

0.347

High

292930

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

3

0

High-throughput

0.342

High

292910

CF141
Uncharacterized protein C6orf141

2

0

High-throughput

0.328

High

292922

F136A
Protein FAM136A

2

0

High-throughput

0.328

High

183206

LAMA5
Laminin subunit alpha-5

1

0

High-throughput

0.279

Low

292888

NDUA3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3

1

0

High-throughput

0.279

Low

292907

COG2
Conserved oligomeric Golgi complex subunit 2

1

0

High-throughput

0.279

Low

292926

NOX5
NADPH oxidase 5

1

0

High-throughput

0.279

Low

292929

LGMN
Legumain

1

0

High-throughput

0.279

Low

292935

SYIM
Isoleucine--tRNA ligase, mitochondrial

1

0

High-throughput

0.279

Low

292939

ICAM5
Intercellular adhesion molecule 5

1

0

High-throughput

0.279

Low

292940

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

0

High-throughput

0.279

Low

292941

DMXL1
DmX-like protein 1

1

0

High-throughput

0.279

Low

292908

CDK10
Cyclin-dependent kinase 10

1

0

High-throughput

0.249

Low

292913

MAMC2
MAM domain-containing protein 2

1

0

High-throughput

0.249

Low

292920

ITLN1
Intelectin-1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025