Protein: SESQ1
Sesquipedalian-1 (Ses1) (27 kDa inositol polyphosphate phosphatase-interacting protein A) (IPIP27A) (PH domain-containing endocytic trafficking adaptor 1)

Gene: SESQ1, PHETA1
Organism: Homo sapiens
Interactions: 41
UniProt ID: Q8N4B1

Gene Ontology (top 5):
GO:0001881 - receptor recycling
GO:0005769 - early endosome
GO:0005802 - trans-Golgi network
GO:0005829 - cytosol
GO:0007032 - endosome organization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1326263

PKHJ1
Pleckstrin homology domain-containing family J member 1

5

16

High-throughput

0.931

High

1233873

SESQ2
Sesquipedalian-2

3

18

High-throughput

0.858

High

222143

NCK2
Cytoplasmic protein NCK2

2

20

High-throughput

0.783

High

250289

VINEX
Vinexin

2

20

High-throughput

0.783

High

987772

GRB2
Growth factor receptor-bound protein 2

2

20

High-throughput

0.783

High

1326264

ABI2
Abl interactor 2

2

20

High-throughput

0.783

High

1034025

OCRL
Inositol polyphosphate 5-phosphatase OCRL

9

10

Small-scale

0.753

High

1326257

PAAF1
Proteasomal ATPase-associated factor 1

1

20

High-throughput

0.691

High

731955

I5P2
Type II inositol 1,4,5-trisphosphate 5-phosphatase

2

10

High-throughput

0.628

High

1326260

CARD9
Caspase recruitment domain-containing protein 9

2

13

High-throughput

0.628

High

1326253

SESQ1
Sesquipedalian-1

1

17

High-throughput

0.621

High

1307414

KRA13
Keratin-associated protein 1-3

2

1

High-throughput

0.606

High

1198029

KR132
Keratin-associated protein 13-2

2

0

High-throughput

0.580

High

1326255

GPX7
Glutathione peroxidase 7

2

4

High-throughput

0.574

High

1326266

SPG7
Mitochondrial inner membrane m-AAA protease component paraplegin

2

6

High-throughput

0.574

High

217149

MS18B
Protein Mis18-beta

2

1

High-throughput

0.553

High

885334

HXA1
Homeobox protein Hox-A1

2

1

High-throughput

0.553

High

254184

CTND1
Catenin delta-1

1

17

High-throughput

0.536

High

539079

UMPS
Uridine 5'-monophosphate synthase

1

2

High-throughput

0.536

High

954536

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

9

High-throughput

0.536

High

1326254

SEN2
tRNA-splicing endonuclease subunit Sen2

1

1

High-throughput

0.536

High

1326261

PABP3
Polyadenylate-binding protein 3

1

12

High-throughput

0.536

High

1326265

VPS4A
Vacuolar protein sorting-associated protein 4A

1

13

High-throughput

0.536

High

2813

A0A0C3SFZ9
FCH and mu domain containing endocytic adaptor 1

1

7

High-throughput

0.515

High

1186767

KRA63
Keratin-associated protein 6-3

1

0

High-throughput

0.493

High

1119512

PEBB
Core-binding factor subunit beta

1

2

High-throughput

0.489

High

1248226

CSPG4
Chondroitin sulfate proteoglycan 4

1

2

High-throughput

0.489

High

1326258

DPCD
Protein DPCD

1

1

High-throughput

0.489

High

1326259

SIL1
Nucleotide exchange factor SIL1

1

2

High-throughput

0.489

High

155683

FCHO1
F-BAR domain only protein 1

1

6

High-throughput

0.481

High

791530

SYUA
Alpha-synuclein

1

4

High-throughput

0.481

High

138217

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

6

High-throughput

0.479

High

173066

XPO1
Exportin-1

1

20

High-throughput

0.479

High

1276216

ATG9A
Autophagy-related protein 9A

1

3

High-throughput

0.479

High

1145271

RNPS1
RNA-binding protein with serine-rich domain 1

1

17

High-throughput

0.445

High

70352

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

1326262

CK068
UPF0696 protein C11orf68

2

0

High-throughput

0.316

High

1230781

ANR40
Ankyrin repeat domain-containing protein 40

1

0

High-throughput

0.279

Low

1242436

WDR73
Integrator complex assembly factor WDR73

1

0

High-throughput

0.279

Low

1326256

RMD3
Regulator of microtubule dynamics protein 3

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025